Protein Alignment hll and Acsl1

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001289092.1
• Gene: Acsl1 / 14081
• MGIID: 102797
• Length: 699
• Species: Mus musculus
• Alignment Length: 677
• Identity: 172/677 - (25%)
• Similarity: 290/677 - (42%)
• Gaps: 105/677 - (15%)

  Fly    36 QTIPEFFKESCEKYSDLPALVWETPGSGNDGWTTLTFGEYQERVEQAALMLLSVGVEERSS--VG 98
            :|:.:.|:...:..::.|.|....|   |..:..:::.|..|..|.....|:..|.:..|.  :|
Mouse    91 RTMYDGFQRGIQVSNNGPCLGSRKP---NQPYEWISYKEVAELAECIGSGLIQKGFKPCSEQFIG 152

  Fly    99 ILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVLATGESSVCVVDDAQQMAK--LRAIKE 161
            :.:.|.|||...|.|......||..:|.:..|:|:.:::...|.|| :..|..:.||  |..::.
Mouse   153 LFSQNRPEWVIVEQGCFSYSMVVVPLYDTLGADAITYIVNKAELSV-IFADKPEKAKLLLEGVEN 216

  Fly   162 RL-PRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELKEELLARESRIR-----ANECAML 220
            :| |.||.::.:.......|:.      .:|...:..|.:..|: |.|.:|::     ..:.|::
Mouse   217 KLTPCLKIIVIMDSYGSDLVER------GKKCGVEIISLKALED-LGRVNRVKPKPPEPEDLAII 274

  Fly   221 IFTSGTVGMPKAVMLSHDNLVFD-------TKSA-AAHMQDIQVGKESFVSYLPLSHVAAQIFDV 277
            .|||||.|.||..|::|.|::.|       |:|| .|...|:      .:|:|||:|:...:.:.
Mouse   275 CFTSGTTGNPKGAMITHQNIINDCSGFIKATESAFIASTDDV------LISFLPLAHMFETVVEC 333

  Fly   278 FLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEKLQERLVAAEAKARPYSRLLLAR 342
            .: |.|...:.|...|.  ..|:...:..:||....|||:..::.:| :..:|.......||...
Mouse   334 VM-LCHGAKIGFFQGDI--RLLMDDLKVLQPTIFPVVPRLLNRMFDR-IFGQANTSLKRWLLDFA 394

  Fly   343 ARAAVAEHQTTLMAGKSPSIYGNAKYWLACRVVKPIREMIGVDNCRVFFTGGAPTSEELKQFFLG 407
            ::...||    |.:|    |..|...|... :...|:..:| ...|:..||.||.|..:..|
Mouse   395 SKRKEAE----LRSG----IVRNNSLWDKL-IFHKIQSSLG-GKVRLMITGAAPVSATVLTF--- 446

  Fly   408 LDIALG----ECYGMSETSGAITLNVDISNLYSAGQA-----CEGVTL-KIHEPD---CNGQGEI 459
            |..|||    |.||.:|.:....|:  :...::||..     |..|.| .:.|.:   ..|:||:
Mouse   447 LRTALGCQFYEGYGQTECTAGCCLS--LPGDWTAGHVGAPMPCNYVKLVDVEEMNYLASKGEGEV 509

  Fly   460 LMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKELIITAGGENIPPVHI 524
            .::|..||.|||..|.:|.|.:.:|||||:||:|...|.|.|.|..|.|.:...|.||.|.|..|
Mouse   510 CVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKI 574

  Fly   525 EEL-IKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIEWLRDLDIHETRLS 588
            |.: ::.|  .|:.|.:.|:..:...:.:.:.......:......|:....|..|:.||::..|.
Mouse   575 ENIYLRSE--AVAQVFVHGESLQAFLIAVVVPDVESLPSWAQKRGLQGSFEELCRNKDINKAILD 637

  Fly   589 ELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISNAQKVQKFALIAHEFSVA 653
            :||.:                           ..|.|:|        ..::|:..|:....||:.
Mouse   638 DLLKL---------------------------GKEAGLK--------PFEQVKGIAVHPELFSID 667

  Fly   654 TGELGPTLKIRRNIVHAKYAKVIERLY 680
            .|.|.||||.:|..:...:...|:.||
Mouse   668 NGLLTPTLKAKRPELRNYFRSQIDELY 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	165/649 (25%)
Acsl1	NP_001289092.1	LC-FACS_euk	117..695	CDD:341250	166/648 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810