Protein Alignment hll and zgc:158482

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001076488.1
• Gene: zgc:158482 / 100009650
• ZFINID: ZDB-GENE-070209-32
• Length: 619
• Species: Danio rerio
• Alignment Length: 654
• Identity: 125/654 - (19%)
• Similarity: 216/654 - (33%)
• Gaps: 191/654 - (29%)

  Fly    35 PQTIP-EFFKESCEKYSDLPALVWETPGSGNDGWTTLTFGEYQERVEQAALMLL-SVGVEERSSV 97
            |..:| :.|.:..|.....|.:|:|        ..|||:.:......:.|..|| ..|:....:.
Zfish    51 PVFLPVDRFLQQAEARPHKPFIVFE--------GQTLTYRDADRESNRIANALLRECGMRAGDTA 107

  Fly    98 GILAFNCPEWFFAEFGALRAGAVVAGVYPS--------------------NSAE---AVHHV-LA 138
            .:...|.|.:........:.|...|.:..|                    .||:   ||..| :.
Zfish   108 ALFITNQPAFILCWIALAKLGCACALLNTSIRDDSLIRSFRCCRGAKVLIASADLQAAVQQVCVP 172

  Fly   139 TGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELKE 203
            ..:..|||:....:.:.:|::.                             :..||   ||:...
Zfish   173 LQQDGVCVLMMGMECSGMRSLS-----------------------------RAAQE---SSDTAV 205

  Fly   204 ELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQVGKESFVSY--LP 266
            ....| :.:..|..|:.|:||||.|:|||.:::...|:    ::.|.:..|.| ..:.|.|  ||
Zfish   206 PAAVR-AHLTNNTPAVYIYTSGTTGLPKAAVITQTRLL----ASLAVLPSIGV-THTDVLYVTLP 264

  Fly   267 LSHVAAQIFDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEKLQERLVAAEAK 331
            |.|.|.     || :...|||.......|:             :.|...|.:::.:...|.....
Zfish   265 LYHTAG-----FL-IGFMGCVETGSSMVLR-------------RKFSASRFWDECRAHEVTVVQY 310

  Fly   332 ARPYSRLLLARARAAVAEHQTTLMAGKSPSIYGNAKYWLACRVVKPIREMIGVDNCRVFFTGGAP 396
            .....|.|....:.||.:|....:|      .||.   |...|.:...:..|
Zfish   311 IGEILRYLCNTPQRAVDQHHAVRLA------IGNG---LRADVWREFLQRFG------------- 353

  Fly   397 TSEELKQFFLGLDIALGECYGMSETSGAITLNVDISNLYSAGQACEGVTLKIH-----------E 450
             ..|:::|:             :.|.|.|........|.:.|:......:.:|           |
Zfish   354 -QMEVREFY-------------ASTEGNIGFLNYTGRLGAVGRVSFLHRMAVHYALIQFDTEREE 404

  Fly   451 PDCNGQGEIL-----MRGRLV--------FMGYLGLPDKTEET------VKEDGWLHSGDLGYID 496
            |..:..|..:     ..|.||        |:||.....:||..      .:.|.:.:||||..:|
Zfish   405 PVRDSSGRCVEVPKGQTGLLVSQITHMAPFVGYAHDEQQTERKRLRDVFRRGDVYFNSGDLMRMD 469

  Fly   497 PKGNLIISGRLKELIITAGGENIPPVHIEELIKKELPCVSNVLLIG----DHRKYLTVLLSLKTK 557
            ....|....|:.: .....|||:....:.:::.. |.||:...:.|    .|
Zfish   470 QDNFLYFIDRVGD-TFRWKGENVATTEVSDVLSL-LECVAEASVYGVCVPGH------------- 519

  Fly   558 CDAKTGIPLDALREETIEWLRDLDIHETRLSELLNIPADLQLPNDTAALAATLEITA-----KPK 617
             :.:.|:....|::......:.:..|.:||......|..|:       |.:::|:|:     |.|
Zfish   520 -EGRIGMAAVKLKDGAEFEQKQVFEHVSRLLPAYARPRFLR-------LQSSMELTSTFKQLKLK 576

  Fly   618 LLEA 621
            |:||
Zfish   577 LVEA 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	118/626 (19%)
zgc:158482	NP_001076488.1	PRK08279	24..619	CDD:236217	125/654 (19%)
		AFD_class_I	76..609	CDD:302604	118/621 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930