Protein Alignment hll and acsbg1

DIOPT Version :10

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_001344904.2
• Gene: acsbg1 / 100006023
• ZFINID: ZDB-GENE-110914-219
• Length: 674
• Species: Danio rerio
• Alignment Length: 688
• Identity: 272/688 - (39%)
• Similarity: 398/688 - (57%)
• Gaps: 52/688 - (7%)

  Fly     4 LKPATSYRSTSLHDAVKLRLDE--PSSFSQTVPPQTIPEFFKESCEKYSDLPALVWETPGSGNDG 66
            |.||.|..:|....:|:||:||  |..      |.|:.:.|..|.:||.:|.||..:   .||.
Zfish    28 LAPAQSLWTTEASGSVQLRMDEHCPEQ------PITVHQMFYNSVQKYGNLTALASK---RGNK- 82

  Fly    67 WTTLTFGEYQERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAE 131
            |...||.||......||...|.:|:|:...|.||.||..|||.|..|.:.||.::||:|.:||.:
Zfish    83 WEKATFLEYYHLCRMAAKGFLKLGLEQFHGVAILGFNSAEWFIAAVGTVFAGGIMAGIYTTNSPD 147

  Fly   132 AVHHVLATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQE-- 194
            |..||.....::|.||::.:|:.|:..:|::||.|||::|..|..:   :.....:||::..|
Zfish   148 ACLHVANDSRANVIVVENQKQLDKIMQVKDKLPHLKAIVQYSGSLK---EKLANLYSWEEFMELG 209

  Fly   195 -QTFSSELKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDT--KSAAAHMQDIQV 256
             :....||.|.:    |:.|||:|.:||:||||.|.||.|||||||:.:..  .|.|..||..::
Zfish   210 LEVSDHELDEVI----SKQRANQCCVLIYTSGTTGSPKGVMLSHDNITWTAHHASRAGDMQPAEI 270

  Fly   257 GKESFVSYLPLSHVAAQIFDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEKL 321
            .:||.||||||||:||||:|::.|:.....::||..|||||||:.:.|:..||...|||||:||:
Zfish   271 RQESLVSYLPLSHIAAQIYDLWTGIKWGEQISFAQPDALKGTLVDSLREVTPTAHMGVPRVWEKI 335

  Fly   322 QERLVAAEAKARPYSRLLLARARAAVAEHQTTLMAGKSPSIYGNAKYWLACR-VVKPIREMIGVD 385
            .|::....::.....|.::..|.:...:....|...:..|..    :.||.: :::.:|..:|..
Zfish   336 MEKIKEGISRCGYMKRKMVTWAMSVSLDANQRLKKDEEKSFL----FTLAEKLILQKLRAELGFS 396

  Fly   386 NCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSETSGAITLN-VDISNLYSAGQACEGVTLKIH 449
            :|..||:|.||...|..||||||:|.|.|.||||||||...:: .:.....|.|:...|...|:.
Zfish   397 SCVKFFSGAAPIGRETLQFFLGLNIRLYEAYGMSETSGPHFMSGPEAYQFLSCGKVVPGCQYKLI 461

  Fly   450 EPDCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKELIITA 514
            ..:.:|.||:...||.||||:|.|.|||:|.:.|||||.|||||.:|..|.:.|:||:|||||||
Zfish   462 NINADGSGEVCFWGRNVFMGFLNLEDKTKEALDEDGWLRSGDLGKVDEDGFIYINGRIKELIITA 526

  Fly   515 GGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIEWLRD 579
            |||||||:.||:.:|:||..:||.:||||.||:|::||:||...:.:|..|.|.|..|.:|:.:.
Zfish   527 GGENIPPLPIEDAVKQELSIISNAMLIGDERKFLSMLLTLKCTVNPETTEPTDILSLEAVEFCQR 591

  Fly   580 LDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLL-EAIEEGIKRANKYAISNAQKVQKF 643
            :....|:||::..                     .|.||: ::||:||.:.|..|.||||::||:
Zfish   592 IGSQSTKLSDITG---------------------GKDKLVYKSIEDGIGQVNSKATSNAQRIQKW 635

  Fly   644 ALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLYK 681
            .::..:||||.||||||:|:||.:|...|...||..|:
Zfish   636 TILDKDFSVAGGELGPTMKLRRPVVLQMYHNEIENFYR 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	Adenylate forming domain, Class I superfamily	62..680	CDD:473059	251/625 (40%)
acsbg1	XP_001344904.2	ACSBG_like	78..672	CDD:341256	251/629 (40%)