Protein Alignment rk and GALR2

DIOPT Version :9

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: NP_003848.1
• Gene: GALR2 / 8811
• HGNCID: 4133
• Length: 387
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 95/377 - (25%)
• Similarity: 150/377 - (39%)
• Gaps: 87/377 - (23%)

  Fly   762 VVFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIP 826
            ::||:..:||..|:.|||.....:......:.||..||..                  |.:..:|
Human    34 LIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLC------------------FILCCVP 80

  Fly   827 WQM-----------SVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYI 880
            :|.           |:||:...||..|:...|.:|||.::|:|..||.:.:|..:..:.:.|  :
Human    81 FQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNA--L 143

  Fly   881 MSVGWVFALIMALMPLVGVSDYRK-----FAVCLPFETTTGPASL---TYVISLM---FINGCAF 934
            .::|.::.|.: |.....:|.||:     ..||.|..:.....::   |:|.|.:   .:.|..:
Human   144 AAIGLIWGLSL-LFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTY 207

  Fly   935 LTLMGCYLKMYW-----AIRGSQAWNTNDSRIAKRMALLVFTDF-LCWSPIAFFSITAIFGLQLI 993
            ...    |:..|     ...||.|  ....|...||.|:|...| |||.|.....:...||  ..
Human   208 ART----LRYLWRAVDPVAAGSGA--RRAKRKVTRMILIVAALFCLCWMPHHALILCVWFG--QF 264

  Fly   994 SLEQA----KIFTVFVLPLNSCCNPFLYAIMTKQFKKDCVTLCKHFEESRVVG--GGGPG---GR 1049
            .|.:|    :|.:..|...|||.||.:||:::|.|:|...|:|        .|  |..||   ||
Human   265 PLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTIC--------AGLLGRAPGRASGR 321

  Fly  1050 ----------GAVARTKRGDLPPPLLPAAAVAHPPGCR--CLRMLPSEMPNW 1089
                      |:|...:..||......|.|:...||..  |: :.|...|:|
Human   322 VCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCI-LEPCPGPSW 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	33/138 (24%)
		7tm_1	770..1017	CDD:278431	68/278 (24%)
GALR2	NP_003848.1	7tm_4	32..>177	CDD:304433	39/163 (24%)
		7tm_1	42..292	CDD:278431	68/278 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910