DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and AT1G65850

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_001185325.1	Gene:	AT1G65850 / 842896	AraportID:	AT1G65850	Length:	1051	Species:	Arabidopsis thaliana

Alignment Length:	697	Identity:	148/697 - (21%)
Similarity:	250/697 - (35%)	Gaps:	230/697 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 EKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSCRGIG 169
            ||..:.|.||||....|..:.|..:...:..|:..:|::.|: |.|        |::|   .|:|
plant   488 EKVEEHLAEKSLNVKQGLHVLTEKSLISIEGGRIKMHNLLEQ-LGK--------EIVR---HGLG 540

  Fly   170 ILAVPVNLPN------------EVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNA 222
              ..|:..|.            |::..|.|:.::..:.   |:.:....||.:|:        .|
plant   541 --HQPIREPGKRQFLVDTRDICELLTNDTGSKSVIGIH---FYSSELSSELNISE--------RA 592

  Fly   223 FYGLAKLKRLSL-QNCGLKS----LPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRL 282
            |.|:..||.|.. ...|.:|    ||    |||..|:                    |||:.|..
plant   593 FEGMPNLKFLRFYYRYGDESDKLYLP----QGLNYLS--------------------QKLKILEW 633

  Fly   283 EGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMK-----ISAGA 342
            :......:|:|...  ..|..||:..:.|..:.:.:.| :.||..:.|..::|:|     .:|..
plant   634 DHFPLTCMPSNFCT--EYLVELNMRFSKLHKLWEGNRP-LANLNWMYLNHSKILKELPDLSTATN 695

  Fly   343 LKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWIND----TELPRS------MQML 397
            |:.|..:|...|.:     ||..:.|.:.||:|        ::|.    .|||.|      :|.|
plant   696 LQELFLVKCSSLVE-----LPSSIGKATNLQKL--------YLNMCTSLVELPSSIGNLHKLQKL 747

  Fly   398 DMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQT 462
            .:.......:.| |...:..|.:|.|:|...|:.|||:..  .:::|||.|..|:|||::: :..
plant   748 TLNGCSKLEVLP-ANINLESLDELDLTDCLVLKRFPEIST--NIKVLKLLRTTIKEVPSSI-KSW 808

  Fly   463 PRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQD 527
            |||:.|||..|.     ||...  :..||:.:...       ||.: ::.::.|...:|..|...
plant   809 PRLRDLELSYNQ-----NLKGF--MHALDIITTMY-------FNDI-EMQEIPLWVKKISRLQTL 858

  Fly   528 AFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLHLK-------- 584
            ...|..||..|                               |:||:|    |.:||
plant   859 ILNGCKKLVSL-------------------------------PQLPDS----LSYLKVVNCESLE 888

  Fly   585 ----TFNNPKLREFPPPDTFPRIQTLILSYAYHCCAFLPLVAMSSQKKTSQVQ---EAVLFPSDA 642
                :|:|||:                      ...|:..:.::.:.|...:|   :..:.|...
plant   889 RLDCSFHNPKM----------------------SLGFINCLKLNKEAKELIIQITTKCTVLPGRE 931

  Fly   643 EFDMTLWNNSMMNIWPQMHNLSKQLGASMHDPWETAINFNEEQLQTQTGGQIATSYMEEYFEEHD 707
            .              |.......:.|:|:.      :|.|...|.|.:..:.....:.:|.:|::
plant   932 V--------------PVYFTHRTKNGSSLR------VNLNRRPLSTASRFKACILLVNKYCKENE 976

  Fly   708 VSGPATGYGFGTGLFS--------GMSTEDFQPGSVQCLPMPGPFLP 746
            |...     ||..:..        |:        .|||.| ...|||
plant   977 VKEV-----FGRKMMKASYCIIDLGL--------DVQCRP-THHFLP 1009

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	5/20 (25%)
		LRR_RI	180..>383	CDD:238064	48/212 (23%)
		leucine-rich repeat	183..204	CDD:275380	3/20 (15%)
		LRR_8	203..263	CDD:290566	17/64 (27%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	10/27 (37%)
		LRR_8	252..311	CDD:290566	10/58 (17%)
		leucine-rich repeat	253..276	CDD:275380	1/22 (5%)
		leucine-rich repeat	277..300	CDD:275380	4/22 (18%)
		LRR_8	299..359	CDD:290566	15/64 (23%)
		leucine-rich repeat	301..324	CDD:275380	5/22 (23%)
		leucine-rich repeat	325..348	CDD:275380	7/27 (26%)
		LRR_RI	327..567	CDD:238064	59/254 (23%)
		leucine-rich repeat	349..371	CDD:275380	5/21 (24%)
		LRR_8	370..425	CDD:290566	15/64 (23%)
		leucine-rich repeat	372..393	CDD:275380	7/24 (29%)
		leucine-rich repeat	394..415	CDD:275380	4/20 (20%)
		leucine-rich repeat	418..486	CDD:275380	25/67 (37%)
		leucine-rich repeat	441..464	CDD:275378	8/22 (36%)
		LRR_8	487..545	CDD:290566	11/57 (19%)
		leucine-rich repeat	487..510	CDD:275380	4/22 (18%)
		leucine-rich repeat	511..534	CDD:275380	4/22 (18%)
		LRR_8	533..589	CDD:290566	11/67 (16%)
		leucine-rich repeat	535..558	CDD:275380	2/22 (9%)
		leucine-rich repeat	559..580	CDD:275380	4/20 (20%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
AT1G65850	NP_001185325.1	PLN03210	46..1048	CDD:215633	148/697 (21%)
		TIR	48..211	CDD:279864
		NK	245..>275	CDD:302627
		leucine-rich repeat	599..627	CDD:275380	11/51 (22%)
		leucine-rich repeat	628..649	CDD:275380	4/22 (18%)
		LRR_3	649..667	CDD:285026	4/17 (24%)
		leucine-rich repeat	650..669	CDD:275380	4/18 (22%)
		LRR_RI	667..894	CDD:238064	69/294 (23%)
		leucine-rich repeat	673..695	CDD:275380	5/21 (24%)
		leucine-rich repeat	696..719	CDD:275380	7/27 (26%)
		leucine-rich repeat	720..743	CDD:275380	8/30 (27%)
		leucine-rich repeat	744..766	CDD:275380	4/22 (18%)
		leucine-rich repeat	767..810	CDD:275380	16/45 (36%)
		leucine-rich repeat	811..854	CDD:275380	13/57 (23%)
		leucine-rich repeat	855..886	CDD:275380	12/65 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340670at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010