DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and AT1G48540

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_175287.2	Gene:	AT1G48540 / 841275	AraportID:	AT1G48540	Length:	1063	Species:	Arabidopsis thaliana

Alignment Length:	770	Identity:	167/770 - (21%)
Similarity:	270/770 - (35%)	Gaps:	206/770 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 YVH-----LQHLQQQQQQNP--------------QTVQQLSQITVNRTS-KSASVTPTGIRENVM 98
            |:|     |:.|::.....|              :.::||.:|....|| |..|..|:..|:...
plant    40 YLHLRLDSLRELERMLSNAPVDYLRAYVSDLGDYRALEQLRRILRILTSLKVVSTLPSPARDPTP 104

  Fly    99 LPSADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLR- 162
            | |..|....::|      |.....||| |.|..:|..:.||..|.       ||  .|.:.||
plant   105 L-SLFPFGSLKVL------ELRRCDLST-SPAKGLIELRHTLEKII-------CH--NSTDALRH 152

  Fly   163 -LSCRGIGILAVPVNLP--NEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFY 224
             .:.|    :|...|.|  |::.|:....|.|..:: .|..:.|..|.|.||.|..:.:|  ...
plant   153 VFASR----IAEITNSPEWNKLAVISCACNRLVLMD-ESLQLLPAAESLDLSRNKFVKVD--NLR 210

  Fly   225 GLAKLKRLSLQNCGLKSLPPQSF--QGLAQLTSLQLNGNALVSLDG------------------- 268
            ...|||.|.|   |...|...|:  |....|..|.|..|||.:|.|
plant   211 RCTKLKHLDL---GFNHLRTVSYLSQVSCHLVKLVLRNNALTTLRGIENLKSLQGLDVSYNIISN 272

  Fly   269 ----DCLGHLQKLRTLRLEGN-----LFYRIPTNALAGL---RTLEALNLGSNLLTIINDEDFPR 321
                :.|..|.:|:.|.||||     .:||....:...|   ..|:...:|:.       |.:.|
plant   273 FSELEFLWSLSQLKELWLEGNPVCCARWYRAHVFSYVALPDELKLDGKQIGTR-------EFWKR 330

  Fly   322 MPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKL-------SQLQELSITS 379
            .     :::...|....|.|.......      :||...|......|:       |:.:...:.|
plant   331 Q-----IIVAHRQSEPASYGFYSPARE------EDNEEGSCNRKKKKICRLASIHSEAESTYVNS 384

  Fly   380 NRLRWINDTELPRSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPE---------L 435
            :......|.|...:|: .:..|:....||.     :..|:|  ...|..||.|.|         .
plant   385 DHESATCDHENKENMK-FNQEADIFGLISK-----VEHLKK--ERSVLWLREFKEWMDRSTEDFA 441

  Fly   436 EACHALEILKLDR---AGIQEVPANLCRQTPRLKSLELKTNSLKRI-PNL---SSCRDLRLLDLS 493
            :.|...:.:.|::   ..|:|:..:....|||..|..|:.:..|.. .||   .||.|.:   ..
plant   442 DVCKDSQGINLEKKYYTKIREISRHHGGGTPRYTSGSLRASRAKSYRKNLECNGSCVDHK---AG 503

  Fly   494 SNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTA 558
            .:.::.::|   |..:::.|.:.|.:               ||..|........:|.|
plant   504 MDYMKYVEG---NETQKITDDISSIS---------------LQSTDRNQKHQECVHDE------- 543

  Fly   559 LEDLNL-GNNIFP------ELPESGLRALLHL------KTFNNPKLREFPPPDTFPRIQTLILSY 610
            :|.|:: .|::.|      :|.|:|..:.|.:      .|:          |.:.|..|..:| |
plant   544 MESLSVEPNDLLPTTLAKEKLAENGNMSTLDITQHMTGSTY----------PGSPPHYQKDVL-Y 597

  Fly   611 AYHCCA--FLPLVA----MSSQKKTSQVQEAVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGA 669
            ..|...  .|.|.|    ::|...||...|...:.|::|:     :|........:.|::: ||.
plant   598 RRHNLVEEILQLSADSYSVASSDSTSSCSEDDNYDSESEY-----SNHKEGRLTDLLNVNR-LGK 656

  Fly   670 SMHDPWETAINFNEEQLQTQTGGQIATSYMEEYFEEHDVSGPATGYGFGTGLFSG 724
            .:.:.......|...  |.:.|..|.|...:|..:|       |...|.:||.:|
plant   657 EILECTPKGTRFLGS--QPENGSTIKTLRTDESMKE-------TTTNFPSGLHNG 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	6/24 (25%)
		LRR_RI	180..>383	CDD:238064	52/242 (21%)
		leucine-rich repeat	183..204	CDD:275380	4/20 (20%)
		LRR_8	203..263	CDD:290566	20/61 (33%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	8/24 (33%)
		LRR_8	252..311	CDD:290566	21/89 (24%)
		leucine-rich repeat	253..276	CDD:275380	10/45 (22%)
		leucine-rich repeat	277..300	CDD:275380	9/30 (30%)
		LRR_8	299..359	CDD:290566	9/59 (15%)
		leucine-rich repeat	301..324	CDD:275380	4/22 (18%)
		leucine-rich repeat	325..348	CDD:275380	3/22 (14%)
		LRR_RI	327..567	CDD:238064	48/263 (18%)
		leucine-rich repeat	349..371	CDD:275380	4/28 (14%)
		LRR_8	370..425	CDD:290566	10/54 (19%)
		leucine-rich repeat	372..393	CDD:275380	3/20 (15%)
		leucine-rich repeat	394..415	CDD:275380	4/20 (20%)
		leucine-rich repeat	418..486	CDD:275380	21/83 (25%)
		leucine-rich repeat	441..464	CDD:275378	4/25 (16%)
		LRR_8	487..545	CDD:290566	7/57 (12%)
		leucine-rich repeat	487..510	CDD:275380	2/22 (9%)
		leucine-rich repeat	511..534	CDD:275380	2/22 (9%)
		LRR_8	533..589	CDD:290566	14/68 (21%)
		leucine-rich repeat	535..558	CDD:275380	5/22 (23%)
		leucine-rich repeat	559..580	CDD:275380	7/27 (26%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
AT1G48540	NP_175287.2	leucine-rich repeat	113..149	CDD:275380	14/51 (27%)
		leucine-rich repeat	150..192	CDD:275380	11/46 (24%)
		LRR_RI	<189..297	CDD:238064	32/112 (29%)
		leucine-rich repeat	194..214	CDD:275378	6/21 (29%)
		leucine-rich repeat	215..237	CDD:275378	8/24 (33%)
		LRR_8	237..295	CDD:290566	16/57 (28%)
		leucine-rich repeat	238..259	CDD:275378	8/20 (40%)
		leucine-rich repeat	260..284	CDD:275378	2/23 (9%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910