DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rk and RLP50

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_567412.1 Gene:RLP50 / 827026 AraportID:AT4G13920 Length:891 Species:Arabidopsis thaliana


Alignment Length:672 Identity:169/672 - (25%)
Similarity:259/672 - (38%) Gaps:172/672 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 VVVLDLGNNNLT-KLEAN-SFFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLP 243
            ||.|||||::|. :|.:| |.|...:|:.|.||.|.:....|::......|:.|:|..|.|....
plant    81 VVELDLGNSDLNGRLRSNSSLFRLQHLQSLDLSYNDLSCTLPDSSGNFKYLRVLNLLGCNLFGEI 145

  Fly   244 PQSFQGLAQLTSLQLNGNALVSLDG---DCLGHLQKLRTLRLEGNLFY-RIPTNALAGLRTLEAL 304
            |.|.:.|:.||.|.|:.|.  .|.|   |.:|:|:.||.|.|....|. :|| ::|..|..|..|
plant   146 PTSLRSLSYLTDLDLSYND--DLTGEILDSMGNLKHLRVLSLTSCKFTGKIP-SSLGNLTYLTDL 207

  Fly   305 NLGSNLLTIINDEDFPRMPNLIVLLLKR-NQIMKI--SAGALKNLTALKV--------------- 351
            :|..|..|....:....:.:|.||.|.| |...||  |.|:|.|||.|.:               
plant   208 DLSWNYFTGELPDSMGNLKSLRVLNLHRCNFFGKIPTSLGSLSNLTDLDISKNEFTSEGPDSMSS 272

  Fly   352 -------------------LELDDNLISS-LPEGLSKLSQLQELSITSNRLRWINDTELPRSMQM 396
                               ::|..|...: ||..:|.||:|:...|:.|..    ...:|.|:.|
plant   273 LNRLTDFQLMLLNLSSLTNVDLSSNQFKAMLPSNMSSLSKLEAFDISGNSF----SGTIPSSLFM 333

  Fly   397 ------LDMRANPLS-TISPGAFRGMSKLRKLILSDVR----TLRSFPELEACHALEILKLDRAG 450
                  ||:..|..| .:..|.....|.|::|.:.:..    ..||..:|....||.:...|..|
plant   334 LPSLIKLDLGTNDFSGPLKIGNISSPSNLQELYIGENNINGPIPRSILKLVGLSALSLSFWDTGG 398

  Fly   451 IQEVPANLCRQTPRLKSLE-----LKTNSLKRIPN------LSSCR------------DLRLLDL 492
            |  |..::..|...|:||:     |..:|...:|:      ||||.            .|..||:
plant   399 I--VDFSIFLQLKSLRSLDLSGINLNISSSHHLPSHMMHLILSSCNISQFPKFLENQTSLYHLDI 461

  Fly   493 SSNQIE------------------------------------------KIQGKPFNGLKQLNDLL 515
            |:||||                                          |..|:....:.::..|:
plant   462 SANQIEGQVPEWLWRLPTLRYVNIAQNAFSGELTMLPNPIYSFIASDNKFSGEIPRAVCEIGTLV 526

  Fly   516 LSYNRIKALPQDAFQGIPK-LQLLDLEGNEIS-YIHKEAFSGFTALEDLNLGNN-IFPELPESGL 577
            ||.|.........|:...| |.:|.|..|.:| .|.:|:..|:  |..|::|:| :..:.|:|  
plant   527 LSNNNFSGSIPPCFEISNKTLSILHLRNNSLSGVIPEESLHGY--LRSLDVGSNRLSGQFPKS-- 587

  Fly   578 RALLHLKTFNNPKLREFPPPDTF-------PRIQTLIL-SYAYHCCAFLPLVAMSSQKKTSQVQE 634
              |::........:.|....|||       |.:|.|:| |..:|...|.|..::|..|       
plant   588 --LINCSYLQFLNVEENRINDTFPSWLKSLPNLQLLVLRSNEFHGPIFSPGDSLSFSK------- 643

  Fly   635 AVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGASMHD-----PWETAINFNEEQLQTQTGGQI 694
             :.|     ||::  .|....:.|..:.:...:.:|..|     |..|.:..::|.........|
plant   644 -LRF-----FDIS--ENRFSGVLPSDYFVGWSVMSSFVDIIDNTPGFTVVGDDQESFHKSVVLTI 700

  Fly   695 ATSYME------EYFEEHDVSG 710
            ....||      |.::..||||
plant   701 KGLNMELVGSGFEIYKTIDVSG 722

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064 75/245 (31%)
leucine-rich repeat 183..204 CDD:275380 10/22 (45%)
LRR_8 203..263 CDD:290566 19/59 (32%)
leucine-rich repeat 205..228 CDD:275380 6/22 (27%)
leucine-rich repeat 229..252 CDD:275380 8/22 (36%)
LRR_8 252..311 CDD:290566 23/62 (37%)
leucine-rich repeat 253..276 CDD:275380 10/25 (40%)
leucine-rich repeat 277..300 CDD:275380 9/23 (39%)
LRR_8 299..359 CDD:290566 22/96 (23%)
leucine-rich repeat 301..324 CDD:275380 5/22 (23%)
leucine-rich repeat 325..348 CDD:275380 13/25 (52%)
LRR_RI 327..567 CDD:238064 82/355 (23%)
leucine-rich repeat 349..371 CDD:275380 7/56 (13%)
LRR_8 370..425 CDD:290566 15/61 (25%)
leucine-rich repeat 372..393 CDD:275380 4/20 (20%)
leucine-rich repeat 394..415 CDD:275380 6/27 (22%)
leucine-rich repeat 418..486 CDD:275380 22/94 (23%)
leucine-rich repeat 441..464 CDD:275378 6/22 (27%)
LRR_8 487..545 CDD:290566 20/100 (20%)
leucine-rich repeat 487..510 CDD:275380 10/64 (16%)
leucine-rich repeat 511..534 CDD:275380 5/22 (23%)
LRR_8 533..589 CDD:290566 16/58 (28%)
leucine-rich repeat 535..558 CDD:275380 8/23 (35%)
leucine-rich repeat 559..580 CDD:275380 6/21 (29%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
RLP50NP_567412.1 leucine-rich repeat 494..517 CDD:275380 2/22 (9%)
leucine-rich repeat 524..546 CDD:275380 5/21 (24%)
leucine-rich repeat 547..569 CDD:275380 7/21 (33%)
leucine-rich repeat 570..593 CDD:275380 7/26 (27%)
leucine-rich repeat 594..617 CDD:275380 4/22 (18%)
leucine-rich repeat 618..643 CDD:275380 8/24 (33%)
leucine-rich repeat 644..705 CDD:275380 11/67 (16%)
leucine-rich repeat 707..738 CDD:275380 5/16 (31%)
leucine-rich repeat 739..762 CDD:275380
leucine-rich repeat 763..786 CDD:275380
PLN00113 1..>823 CDD:331614 169/672 (25%)
leucine-rich repeat 81..94 CDD:275381 8/12 (67%)
leucine-rich repeat 107..130 CDD:275380 6/22 (27%)
leucine-rich repeat 131..154 CDD:275380 8/22 (36%)
leucine-rich repeat 155..179 CDD:275380 10/25 (40%)
leucine-rich repeat 180..203 CDD:275380 9/23 (39%)
leucine-rich repeat 204..227 CDD:275380 5/22 (23%)
leucine-rich repeat 228..251 CDD:275380 11/22 (50%)
leucine-rich repeat 252..288 CDD:275380 3/35 (9%)
leucine-rich repeat 289..312 CDD:275380 6/22 (27%)
leucine-rich repeat 313..336 CDD:275380 6/26 (23%)
PLN00113 <355..>418 CDD:331614 16/64 (25%)
leucine-rich repeat 362..385 CDD:275380 5/22 (23%)
leucine-rich repeat 386..410 CDD:275380 7/25 (28%)
leucine-rich repeat 433..455 CDD:275380 4/21 (19%)
leucine-rich repeat 456..479 CDD:275380 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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