DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and RLP47

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_001190722.1	Gene:	RLP47 / 827015	AraportID:	AT4G13810	Length:	706	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	142/570 - (24%)
Similarity:	231/570 - (40%)	Gaps:	144/570 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 HSICERWLQKHCHCTGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLT-KLEAN-SFFMAP 203
            :::.|:| :.:..|          |...|:...|..  ..||.|||..::|. .|.:| |.|...
plant    58 YAMTEKW-RNNTDC----------CSWDGVSCDPKT--GVVVELDLQYSHLNGPLRSNSSLFRLQ 109

  Fly   204 NLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDG 268
            :|::|.|..|.:..:.|::...|.:||.|.|.||.|....|.|...|:.||.|.|:.|...|...
plant   110 HLQKLVLGSNHLSGILPDSIGNLKRLKVLVLVNCNLFGKIPSSLGNLSYLTHLDLSYNDFTSEGP 174

  Fly   269 DCLGHLQKL--RTLRLEGNLFYRIPTNALAG--LRTLEALNLGSNL----LTIINDEDFPRMPNL 325
            |.:|:|.:|  ..|:|....:..:..|.|.|  |:....::|.|.:    |...|..:||:.
plant   175 DSMGNLNRLTDMLLKLSSVTWIDLGDNQLKGINLKISSTVSLPSPIEYLGLLSCNISEFPKF--- 236

  Fly   326 IVLLLKRNQIMKISAGALKNLTALKVLELDDNLI-SSLPEGLSKLSQLQELSITSNRLRWINDTE 389
                             |:|.|:|:.|::..|.| ..:||.|..|.:|:.::|:.|.   .|..|
plant   237 -----------------LRNQTSLEYLDISANQIEGQVPEWLWSLPELRYVNISHNS---FNGFE 281

  Fly   390 LP-------RSMQMLDMRAN------PLSTI--------SPGAFRG--------MSKLRKLILSD 425
            .|       |.:.:||:.:|      ||..:        |...|.|        :..||.|:||:
plant   282 GPADVIQGGRELLVLDISSNIFQDPFPLLPVVSMNYLFSSNNRFSGEIPKTICELDNLRILVLSN 346

  Fly   426 VRTLRSFPE-LEACHALEILKL---DRAGI--QEVPANLCRQTPRLKSLELKTNSLK-RIP-NLS 482
            .....|.|. .|..| |.:|.|   :.:||  :|..::      .|:|.::..|... .:| :|.
plant   347 NNFSGSIPRCFENLH-LYVLHLRNNNLSGIFPEEAISH------HLQSFDVGHNLFSGELPKSLI 404

  Fly   483 SCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLL----------------LSYNRIK--------- 522
            :|.|:..|::..|:|..........|..|..|:                ||::|::
plant   405 NCSDIEFLNVEDNRINDTFPSWLELLPNLQILVLRSNEFYGPIFSPGDSLSFSRLRIFDISENRF 469

  Fly   523 --ALPQDAFQGIPKL-QLLDLEGNEISY---------IHKEAF------------SGFTALEDLN 563
              .||.|.|.|...: .::|::|..|.|         .||...            ||||..:.::
plant   470 TGVLPSDYFVGWSVMSSVVDIDGRIIQYTVTGIDRDFYHKSVALINKGLKMELVGSGFTIYKTID 534

  Fly   564 L-GNNIFPELPES-G-LRALLHLKTFNNPKLREFPPP-DTFPRIQTLILS 609
            : ||.:..::||| | |:.::.|...||......||. .....:|:|.||
plant   535 VSGNRLEGDIPESIGLLKEVIVLSMSNNAFTGHIPPSLSNLSNLQSLDLS 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	3/20 (15%)
		LRR_RI	180..>383	CDD:238064	62/213 (29%)
		leucine-rich repeat	183..204	CDD:275380	8/22 (36%)
		LRR_8	203..263	CDD:290566	21/59 (36%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	10/22 (45%)
		LRR_8	252..311	CDD:290566	18/66 (27%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	7/26 (27%)
		LRR_8	299..359	CDD:290566	12/63 (19%)
		leucine-rich repeat	301..324	CDD:275380	6/26 (23%)
		leucine-rich repeat	325..348	CDD:275380	2/22 (9%)
		LRR_RI	327..567	CDD:238064	73/327 (22%)
		leucine-rich repeat	349..371	CDD:275380	8/22 (36%)
		LRR_8	370..425	CDD:290566	19/83 (23%)
		leucine-rich repeat	372..393	CDD:275380	6/27 (22%)
		leucine-rich repeat	394..415	CDD:275380	8/42 (19%)
		leucine-rich repeat	418..486	CDD:275380	21/75 (28%)
		leucine-rich repeat	441..464	CDD:275378	6/27 (22%)
		LRR_8	487..545	CDD:290566	16/85 (19%)
		leucine-rich repeat	487..510	CDD:275380	4/22 (18%)
		leucine-rich repeat	511..534	CDD:275380	10/49 (20%)
		LRR_8	533..589	CDD:290566	19/80 (24%)
		leucine-rich repeat	535..558	CDD:275380	9/44 (20%)
		leucine-rich repeat	559..580	CDD:275380	7/23 (30%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
RLP47	NP_001190722.1	LRR_RI	263..>443	CDD:238064	44/189 (23%)
		leucine-rich repeat	267..292	CDD:275380	6/27 (22%)
		leucine-rich repeat	293..338	CDD:275380	8/44 (18%)
		LRR_8	338..395	CDD:290566	18/63 (29%)
		leucine-rich repeat	339..360	CDD:275380	8/20 (40%)
		leucine-rich repeat	385..408	CDD:275380	6/22 (27%)
		leucine-rich repeat	409..432	CDD:275380	4/22 (18%)
		leucine-rich repeat	459..529	CDD:275380	14/69 (20%)
		leucine-rich repeat	513..553	CDD:275380	11/39 (28%)
		leucine-rich repeat	554..577	CDD:275380	5/22 (23%)
		LRR_8	556..612	CDD:290566	9/29 (31%)
		leucine-rich repeat	578..599	CDD:275380	4/7 (57%)
		LRRNT_2	36..79	CDD:285463	5/31 (16%)
		leucine-rich repeat	87..110	CDD:275380	8/22 (36%)
		LRR_8	110..169	CDD:290566	21/58 (36%)
		leucine-rich repeat	111..134	CDD:275380	6/22 (27%)
		leucine-rich repeat	135..158	CDD:275380	10/22 (45%)
		LRR_RI	<150..>301	CDD:238064	45/173 (26%)
		leucine-rich repeat	159..182	CDD:275380	9/22 (41%)
		leucine-rich repeat	183..219	CDD:275380	8/35 (23%)
		leucine-rich repeat	220..242	CDD:275380	6/41 (15%)
		LRR_8	221..277	CDD:290566	18/78 (23%)
		leucine-rich repeat	243..266	CDD:275380	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910