DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rk and AT2G25790

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_180150.1	Gene:	AT2G25790 / 817121	AraportID:	AT2G25790	Length:	960	Species:	Arabidopsis thaliana

Alignment Length:	704	Identity:	160/704 - (22%)
Similarity:	272/704 - (38%)	Gaps:	138/704 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 EKEAQILYEKSLQE--YHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSCRG 167
            |.|..:.::.|:|:  .|.|..|.:||           :.:| .|....|:....:..|.||.:.
plant    31 ELELLLSFKSSIQDPLKHLSSWSYSST-----------NDVC-LWSGVVCNNISRVVSLDLSGKN 83

  Fly   168 IG---ILAVPVNLPNEVVVLDLGNNNLTKLEANSFF--MAPNLEELTLSDNSIINMDPNAFYGLA 227
            :.   :.|....|| .:..::|.||||:....:..|  .:|:|..|.||:|:.....|..|  |.
plant    84 MSGQILTAATFRLP-FLQTINLSNNNLSGPIPHDIFTTSSPSLRYLNLSNNNFSGSIPRGF--LP 145

  Fly   228 KLKRLSLQNCGLKSLPPQSFQG--------LAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEG 284
            .|..|.|.|        ..|.|        .:.|..|.|.||.|.......||:|.:|..|.|..
plant   146 NLYTLDLSN--------NMFTGEIYNDIGVFSNLRVLDLGGNVLTGHVPGYLGNLSRLEFLTLAS 202

  Fly   285 N-LFYRIPTNALAGLRTLEALNLGSNLLT------------------IINDEDFPRMP------- 323
            | |...:|.. |..::.|:.:.||.|.|:                  :.|:...|..|
plant   203 NQLTGGVPVE-LGKMKNLKWIYLGYNNLSGEIPYQIGGLSSLNHLDLVYNNLSGPIPPSLGDLKK 266

  Fly   324 -----------------------NLIVLLLKRNQIMKISAGALKNLTA----LKVLEL-DDNLIS 360
                                   |||.|....|.:    :|.:..|.|    |::|.| .:||..
plant   267 LEYMFLYQNKLSGQIPPSIFSLQNLISLDFSDNSL----SGEIPELVAQMQSLEILHLFSNNLTG 327

  Fly   361 SLPEGLSKLSQLQELSITSNRLRWINDTELPR--SMQMLDMRANPLSTISPGAFRGMSKLRKLIL 423
            .:|||::.|.:|:.|.:.|||........|.:  ::.:||:..|.|:...|........|.||||
plant   328 KIPEGVTSLPRLKVLQLWSNRFSGGIPANLGKHNNLTVLDLSTNNLTGKLPDTLCDSGHLTKLIL 392

  Fly   424 -SDVRTLRSFPELEACHALEILKLDRAGIQ-EVPANLCR---------------------QTPRL 465
             |:....:..|.|..|.:||.::|...|.. ::|....:                     ..|:|
plant   393 FSNSLDSQIPPSLGMCQSLERVRLQNNGFSGKLPRGFTKLQLVNFLDLSNNNLQGNINTWDMPQL 457

  Fly   466 KSLELKTNS-LKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAF 529
            :.|:|..|. ...:|:.|..:.|:.||||.|:|..:..:......::.||.||.|.|..:.....
plant   458 EMLDLSVNKFFGELPDFSRSKRLKKLDLSRNKISGVVPQGLMTFPEIMDLDLSENEITGVIPREL 522

  Fly   530 QGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLG-NNIFPELPES--GLRALLHLKTFNNPKL 591
            .....|..|||..|..:.....:|:.|..|.||:|. |.:..|:|::  .:.:|:.:...:|...
plant   523 SSCKNLVNLDLSHNNFTGEIPSSFAEFQVLSDLDLSCNQLSGEIPKNLGNIESLVQVNISHNLLH 587

  Fly   592 REFPPPDTFPRIQTLILSYAYHCCA------FLPLVAMSSQKKTSQVQEAVLFPSDAEFDMTLWN 650
            ...|....|..|....:......|:      ..|...:  :|::::....::..:.|.|...|.:
plant   588 GSLPFTGAFLAINATAVEGNIDLCSENSASGLRPCKVV--RKRSTKSWWLIITSTFAAFLAVLVS 650

  Fly   651 N-SMMNIWPQMHNLSKQLGASMHD--PWETAINFNEEQLQTQTGGQIATSYMEE 701
            . .::.::.:.||:.:.......|  .|||.. |:.:.:::.|...|.:|..::
plant   651 GFFIVLVFQRTHNVLEVKKVEQEDGTKWETQF-FDSKFMKSFTVNTILSSLKDQ 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	5/23 (22%)
		LRR_RI	180..>383	CDD:238064	67/266 (25%)
		leucine-rich repeat	183..204	CDD:275380	6/22 (27%)
		LRR_8	203..263	CDD:290566	20/67 (30%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		leucine-rich repeat	229..252	CDD:275380	6/30 (20%)
		LRR_8	252..311	CDD:290566	20/59 (34%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	7/23 (30%)
		LRR_8	299..359	CDD:290566	20/112 (18%)
		leucine-rich repeat	301..324	CDD:275380	8/70 (11%)
		leucine-rich repeat	325..348	CDD:275380	6/22 (27%)
		LRR_RI	327..567	CDD:238064	70/271 (26%)
		leucine-rich repeat	349..371	CDD:275380	9/22 (41%)
		LRR_8	370..425	CDD:290566	16/57 (28%)
		leucine-rich repeat	372..393	CDD:275380	6/22 (27%)
		leucine-rich repeat	394..415	CDD:275380	5/20 (25%)
		leucine-rich repeat	418..486	CDD:275380	21/91 (23%)
		leucine-rich repeat	441..464	CDD:275378	5/44 (11%)
		LRR_8	487..545	CDD:290566	18/57 (32%)
		leucine-rich repeat	487..510	CDD:275380	7/22 (32%)
		leucine-rich repeat	511..534	CDD:275380	6/22 (27%)
		LRR_8	533..589	CDD:290566	15/58 (26%)
		leucine-rich repeat	535..558	CDD:275380	7/22 (32%)
		leucine-rich repeat	559..580	CDD:275380	7/23 (30%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
AT2G25790	NP_180150.1	PLN00113	12..960	CDD:215061	160/704 (23%)
		leucine-rich repeat	74..98	CDD:275380	6/24 (25%)
		leucine-rich repeat	99..124	CDD:275380	6/24 (25%)
		leucine-rich repeat	125..146	CDD:275380	8/22 (36%)
		leucine-rich repeat	147..170	CDD:275380	6/30 (20%)
		leucine-rich repeat	171..194	CDD:275380	9/22 (41%)
		leucine-rich repeat	195..218	CDD:275380	7/23 (30%)
		leucine-rich repeat	219..242	CDD:275380	5/22 (23%)
		leucine-rich repeat	243..266	CDD:275380	3/22 (14%)
		leucine-rich repeat	267..290	CDD:275380	0/22 (0%)
		leucine-rich repeat	291..314	CDD:275380	7/26 (27%)
		leucine-rich repeat	315..336	CDD:275380	8/20 (40%)
		leucine-rich repeat	339..362	CDD:275380	6/22 (27%)
		leucine-rich repeat	363..383	CDD:275380	5/19 (26%)
		leucine-rich repeat	387..405	CDD:275380	7/17 (41%)
		leucine-rich repeat	411..434	CDD:275380	5/22 (23%)
		leucine-rich repeat	435..479	CDD:275380	7/43 (16%)
		leucine-rich repeat	480..498	CDD:275380	7/17 (41%)
		leucine-rich repeat	504..525	CDD:275380	6/20 (30%)
		leucine-rich repeat	528..551	CDD:275380	7/22 (32%)
		leucine-rich repeat	552..575	CDD:275380	7/22 (32%)
		leucine-rich repeat	576..596	CDD:275380	3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000