| Sequence 1: | NP_476702.1 | Gene: | rk / 34819 | FlyBaseID: | FBgn0003255 | Length: | 1360 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001255213.1 | Gene: | LRRC8E / 80131 | HGNCID: | 26272 | Length: | 796 | Species: | Homo sapiens |
| Alignment Length: | 599 | Identity: | 133/599 - (22%) |
|---|---|---|---|
| Similarity: | 199/599 - (33%) | Gaps: | 244/599 - (40%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 35 DETKENPAPDMQN---------------------------SQEQEPYVHLQH------LQQQQQQ 66
Fly 67 N---------------PQTVQQLSQITVNRTSKSASVT-PTGIRENVMLPSADPEKEAQILYEK- 114
Fly 115 ----SLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSCRGIGILAVPV 175
Fly 176 NLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLK 240
Fly 241 SLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIP---TNALAGLRTLE 302
Fly 303 ALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLS 367
Fly 368 KLSQLQELSITSNRLRWINDTELPRSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSF 432
Fly 433 PELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPN-LSSCRDLRLLDLSSNQ 496
Fly 497 IEKIQGKPFNGLKQ-LNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALE 560
Fly 561 DLNLGNNIFPELPE 574 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| rk | NP_476702.1 | leucine-rich repeat | 158..179 | CDD:275380 | 4/20 (20%) |
| LRR_RI | 180..>383 | CDD:238064 | 42/205 (20%) | ||
| leucine-rich repeat | 183..204 | CDD:275380 | 0/20 (0%) | ||
| LRR_8 | 203..263 | CDD:290566 | 15/59 (25%) | ||
| leucine-rich repeat | 205..228 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 229..252 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 252..311 | CDD:290566 | 14/61 (23%) | ||
| leucine-rich repeat | 253..276 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 277..300 | CDD:275380 | 7/25 (28%) | ||
| LRR_8 | 299..359 | CDD:290566 | 12/59 (20%) | ||
| leucine-rich repeat | 301..324 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 325..348 | CDD:275380 | 3/22 (14%) | ||
| LRR_RI | 327..567 | CDD:238064 | 68/241 (28%) | ||
| leucine-rich repeat | 349..371 | CDD:275380 | 6/21 (29%) | ||
| LRR_8 | 370..425 | CDD:290566 | 10/54 (19%) | ||
| leucine-rich repeat | 372..393 | CDD:275380 | 8/20 (40%) | ||
| leucine-rich repeat | 394..415 | CDD:275380 | 0/20 (0%) | ||
| leucine-rich repeat | 418..486 | CDD:275380 | 19/68 (28%) | ||
| leucine-rich repeat | 441..464 | CDD:275378 | 7/22 (32%) | ||
| LRR_8 | 487..545 | CDD:290566 | 26/58 (45%) | ||
| leucine-rich repeat | 487..510 | CDD:275380 | 10/22 (45%) | ||
| leucine-rich repeat | 511..534 | CDD:275380 | 10/22 (45%) | ||
| LRR_8 | 533..589 | CDD:290566 | 14/42 (33%) | ||
| leucine-rich repeat | 535..558 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 559..580 | CDD:275380 | 7/16 (44%) | ||
| 7tm_4 | 764..>892 | CDD:304433 | |||
| 7tm_1 | 770..1017 | CDD:278431 | |||
| LRRC8E | NP_001255213.1 | Pannexin_like | 1..331 | CDD:289311 | |
| leucine-rich repeat | 486..508 | CDD:275380 | 9/69 (13%) | ||
| LRR 1 | 508..529 | 7/25 (28%) | |||
| leucine-rich repeat | 509..527 | CDD:275380 | 6/22 (27%) | ||
| LRR_RI | 520..760 | CDD:238064 | 86/331 (26%) | ||
| LRR 2 | 536..557 | 6/21 (29%) | |||
| leucine-rich repeat | 537..559 | CDD:275380 | 6/22 (27%) | ||
| LRR 3 | 559..579 | 5/46 (11%) | |||
| leucine-rich repeat | 560..583 | CDD:275380 | 8/49 (16%) | ||
| LRR 4 | 583..604 | 6/20 (30%) | |||
| LRR_8 | 584..642 | CDD:290566 | 21/101 (21%) | ||
| leucine-rich repeat | 584..606 | CDD:275380 | 6/21 (29%) | ||
| LRR 5 | 606..627 | 11/64 (17%) | |||
| leucine-rich repeat | 607..631 | CDD:275380 | 12/67 (18%) | ||
| LRR_8 | 630..688 | CDD:290566 | 22/58 (38%) | ||
| LRR 6 | 631..652 | 7/21 (33%) | |||
| leucine-rich repeat | 632..654 | CDD:275380 | 7/22 (32%) | ||
| LRR 7 | 654..675 | 7/20 (35%) | |||
| leucine-rich repeat | 655..677 | CDD:275380 | 8/21 (38%) | ||
| LRR_8 | 676..734 | CDD:290566 | 26/60 (43%) | ||
| LRR 8 | 677..698 | 9/22 (41%) | |||
| leucine-rich repeat | 678..700 | CDD:275380 | 10/23 (43%) | ||
| LRR 9 | 700..721 | 10/21 (48%) | |||
| leucine-rich repeat | 701..723 | CDD:275380 | 10/22 (45%) | ||
| LRR 10 | 723..744 | 6/21 (29%) | |||
| leucine-rich repeat | 724..746 | CDD:275380 | 5/22 (23%) | ||
| LRR 11 | 746..767 | 8/17 (47%) | |||
| leucine-rich repeat | 747..767 | CDD:275380 | 7/16 (44%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||