DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and Drc3

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_083320.1 Gene:Drc3 / 74665 MGIID:1921915 Length:523 Species:Mus musculus


Alignment Length:358 Identity:87/358 - (24%)
Similarity:132/358 - (36%) Gaps:120/358 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   415 MSKLRKLILSDVRTLR-SFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRI 478
            ::|...::..||.:|: .|.        .||::|         ||. |...||.|:|..|.::||
Mouse    34 LAKQEGILFKDVLSLQLDFQ--------NILRID---------NLW-QFENLKKLQLNNNIIERI 80

  Fly   479 PNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGN 543
            ..|::...|..||||.|.||.|:|  .:.|..|.||.||.|||..:  |:...:.|||:|.|..|
Mouse    81 EGLTNLIHLVWLDLSFNNIEAIEG--LDTLVNLEDLSLSNNRISKV--DSLDALVKLQVLSLGNN 141

  Fly   544 EIS------YIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLHLKTFNNPKLREFPPPDTFPR 602
            :||      |:.:     |..|..|:|..|...|..|        .|.|                
Mouse   142 QISNMMNIIYLRR-----FPCLRTLSLAGNPVSEAEE--------YKMF---------------- 177

  Fly   603 IQTLILSYAYHCCAFLPLVAMSSQKKTSQVQEAVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQL 667
                  .|||    ...||.:..::...|::|..........|             ::.:...||
Mouse   178 ------IYAY----LSDLVYLDFRRVDEQMREMAKMKHQYSID-------------ELKHREAQL 219

  Fly   668 GASMHDPWETAINFNEEQLQTQTGGQIATSYMEEY---FEEHDVSGPATGYGFGTGLFSGMSTED 729
                      .:...|||.:.:.        :||:   |.|| ::||.        ||..|.:||
Mouse   220 ----------QMKLEEEQAKQEK--------LEEHKMAFVEH-LNGPF--------LFDSMYSED 257

  Fly   730 FQPGSVQCLPMPGPFLP---------CADLFDW 753
            .:...:..||.....|.         |.::|::
Mouse   258 VEGNKLSYLPGVRELLEAYKDKFVIICLNIFEY 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064
leucine-rich repeat 183..204 CDD:275380
LRR_8 203..263 CDD:290566
leucine-rich repeat 205..228 CDD:275380
leucine-rich repeat 229..252 CDD:275380
LRR_8 252..311 CDD:290566
leucine-rich repeat 253..276 CDD:275380
leucine-rich repeat 277..300 CDD:275380
LRR_8 299..359 CDD:290566
leucine-rich repeat 301..324 CDD:275380
leucine-rich repeat 325..348 CDD:275380
LRR_RI 327..567 CDD:238064 52/158 (33%)
leucine-rich repeat 349..371 CDD:275380
LRR_8 370..425 CDD:290566 1/9 (11%)
leucine-rich repeat 372..393 CDD:275380
leucine-rich repeat 394..415 CDD:275380 87/358 (24%)
leucine-rich repeat 418..486 CDD:275380 18/68 (26%)
leucine-rich repeat 441..464 CDD:275378 6/22 (27%)
LRR_8 487..545 CDD:290566 26/57 (46%)
leucine-rich repeat 487..510 CDD:275380 11/22 (50%)
leucine-rich repeat 511..534 CDD:275380 9/22 (41%)
LRR_8 533..589 CDD:290566 18/61 (30%)
leucine-rich repeat 535..558 CDD:275380 9/28 (32%)
leucine-rich repeat 559..580 CDD:275380 6/20 (30%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
Drc3NP_083320.1 LRR 1 44..65 10/38 (26%)
leucine-rich repeat 47..66 CDD:275378 8/36 (22%)
PPP1R42 53..200 CDD:411060 58/207 (28%)
LRR 2 66..87 8/20 (40%)
leucine-rich repeat 67..88 CDD:275378 8/20 (40%)
LRR 3 88..109 10/22 (45%)
leucine-rich repeat 89..110 CDD:275378 11/22 (50%)
LRR 4 110..131 9/22 (41%)
leucine-rich repeat 111..132 CDD:275378 9/22 (41%)
LRR 5 132..153 9/20 (45%)
leucine-rich repeat 133..157 CDD:275378 9/28 (32%)
leucine-rich repeat 158..169 CDD:275378 4/10 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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