Protein Alignment rk and SSTR2

DIOPT Version :9

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: NP_001041.1
• Gene: SSTR2 / 6752
• HGNCID: 11331
• Length: 369
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 63/282 - (22%)
• Similarity: 127/282 - (45%)
• Gaps: 27/282 - (9%)

  Fly   761 WVVFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAI 825
            :||.::.|.||..|::|:|.......:....:.|||.||....:.|..||:         ::..:
Human    51 FVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAM---------QVALV 106

  Fly   826 PWQM-SVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFAL 889
            .|.. ..:|::...:..::...|::.|.|::::|..|:.|.|...|....:.|..|....|..:|
Human   107 HWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSL 171

  Fly   890 --IMALMPLVGV--SDYRKFAVCLPFETTTGPASLTYVISLMFINGCAFLTLMG-CYLKMYWAIR 949
              |:.:|...|:  :.:.:.:..:.:...:|.....::|....:.....||::. |||.:...::
Human   172 LVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVK 236

  Fly   950 ------GSQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQLIS----LEQAKIFTVF 1004
                  ||.....::.::.:.::::|.....||.|...|:::::  ...||    |:....|.|.
Human   237 SSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSV--SMAISPTPALKGMFDFVVV 299

  Fly  1005 VLPLNSCCNPFLYAIMTKQFKK 1026
            :...|||.||.|||.::..|||
Human   300 LTYANSCANPILYAFLSDNFKK 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	29/130 (22%)
		7tm_1	770..1017	CDD:278431	54/262 (21%)
SSTR2	NP_001041.1	7tmA_SSTR2	44..323	CDD:320637	63/282 (22%)
		TM helix 1	45..71	CDD:320637	8/19 (42%)
		TM helix 2	78..104	CDD:320637	8/34 (24%)
		TM helix 3	115..145	CDD:320637	6/29 (21%)
		TM helix 4	157..179	CDD:320637	5/21 (24%)
		TM helix 5	205..234	CDD:320637	6/28 (21%)
		TM helix 6	249..279	CDD:320637	5/29 (17%)
		TM helix 7	291..316	CDD:320637	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910