DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and Ppp1r7

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_075689.1 Gene:Ppp1r7 / 66385 MGIID:1913635 Length:361 Species:Mus musculus


Alignment Length:334 Identity:87/334 - (26%)
Similarity:151/334 - (45%) Gaps:81/334 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   264 VSLDGDC----LGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPN 324
            ::||.|.    |.|   .|..::||          |..|:.:::|.|..||:..|  |:...:.:
Mouse    73 INLDRDAEDVDLTH---YRIGKIEG----------LEVLKKVKSLCLRQNLIKCI--ENLEELQS 122

  Fly   325 LIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTE 389
            |..|.|..|||.||.  .|:.||.|:||::..|::.:: ||:.||:||::|.:.:|::..|.:..
Mouse   123 LRELDLYDNQIKKIE--NLEALTELEVLDISFNMLRNI-EGIDKLTQLKKLFLVNNKINKIENIS 184

  Fly   390 LPRSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEV 454
            ....:|||::.:|.:..|                .::.||.:                       
Mouse   185 NLHQLQMLELGSNRIRAI----------------ENIDTLTN----------------------- 210

  Fly   455 PANLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYN 519
                      |:||.|..|.:.::.||.:..:|.:|.:.||::.||:|  ...|..|.:|.||.|
Mouse   211 ----------LESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEG--LQSLVNLRELYLSNN 263

  Fly   520 RIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNI---FPELPE-SGLRAL 580
            .|:.:  :..:...||.:||:..|.|..|  |..|..|.|::..:.:|:   :.:|.| .|.|:|
Mouse   264 GIEVI--EGLENNNKLTMLDIASNRIKKI--ENISHLTELQEFWMNDNLLESWSDLDELKGARSL 324

  Fly   581 LHLKTFNNP 589
            ..:....||
Mouse   325 ETVYLERNP 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064 39/122 (32%)
leucine-rich repeat 183..204 CDD:275380
LRR_8 203..263 CDD:290566
leucine-rich repeat 205..228 CDD:275380
leucine-rich repeat 229..252 CDD:275380
LRR_8 252..311 CDD:290566 13/50 (26%)
leucine-rich repeat 253..276 CDD:275380 5/15 (33%)
leucine-rich repeat 277..300 CDD:275380 5/22 (23%)
LRR_8 299..359 CDD:290566 21/59 (36%)
leucine-rich repeat 301..324 CDD:275380 6/22 (27%)
leucine-rich repeat 325..348 CDD:275380 10/22 (45%)
LRR_RI 327..567 CDD:238064 62/239 (26%)
leucine-rich repeat 349..371 CDD:275380 8/21 (38%)
LRR_8 370..425 CDD:290566 10/54 (19%)
leucine-rich repeat 372..393 CDD:275380 4/20 (20%)
leucine-rich repeat 394..415 CDD:275380 5/20 (25%)
leucine-rich repeat 418..486 CDD:275380 9/67 (13%)
leucine-rich repeat 441..464 CDD:275378 0/22 (0%)
LRR_8 487..545 CDD:290566 19/57 (33%)
leucine-rich repeat 487..510 CDD:275380 8/22 (36%)
leucine-rich repeat 511..534 CDD:275380 6/22 (27%)
LRR_8 533..589 CDD:290566 17/59 (29%)
leucine-rich repeat 535..558 CDD:275380 8/22 (36%)
leucine-rich repeat 559..580 CDD:275380 6/24 (25%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
Ppp1r7NP_075689.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..64
LRR 1 78..99 7/33 (21%)
LRR_4 99..140 CDD:289563 14/44 (32%)
LRR 2 100..121 6/22 (27%)
leucine-rich repeat 101..122 CDD:275380 6/22 (27%)
LRR_4 121..163 CDD:289563 17/44 (39%)
LRR_8 122..177 CDD:290566 23/57 (40%)
LRR 3 122..143 9/22 (41%)
leucine-rich repeat 123..144 CDD:275380 10/22 (45%)
LRR_4 143..185 CDD:289563 14/42 (33%)
LRR 4 144..165 7/21 (33%)
leucine-rich repeat 145..166 CDD:275380 8/21 (38%)
LRR_8 165..221 CDD:290566 17/104 (16%)
LRR 5 166..187 5/20 (25%)
leucine-rich repeat 167..188 CDD:275380 4/20 (20%)
LRR_4 188..227 CDD:289563 12/87 (14%)
LRR 6 188..209 6/36 (17%)
leucine-rich repeat 189..210 CDD:275380 7/36 (19%)
LRR_4 209..251 CDD:289563 14/76 (18%)
LRR 7 210..231 7/53 (13%)
leucine-rich repeat 211..232 CDD:275380 7/20 (35%)
LRR_8 231..287 CDD:290566 19/59 (32%)
LRR 8 232..253 7/22 (32%)
leucine-rich repeat 233..254 CDD:275380 8/22 (36%)
LRR_4 254..295 CDD:289563 14/44 (32%)
LRR 9 254..275 6/22 (27%)
leucine-rich repeat 255..276 CDD:275380 6/22 (27%)
LRR_4 276..317 CDD:289563 13/42 (31%)
LRR 10 276..297 9/22 (41%)
leucine-rich repeat 277..298 CDD:275380 8/22 (36%)
LRR 11 298..319 4/20 (20%)
LRRcap 337..355 CDD:197729
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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