DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and LOC571410

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_693932.2	Gene:	LOC571410 / 571410	-ID:	-	Length:	338	Species:	Danio rerio

Alignment Length:	283	Identity:	58/283 - (20%)
Similarity:	114/283 - (40%)	Gaps:	46/283 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   769 LGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAI-VDAATLGEFRMFAIPWQMSVL 832
            |||..|::.:..||:........|.:||.||..:|:....||: ||......|..
Zfish    22 LGNVLVIWAVWSSRALRQTTFCFVVSLAVADLLVGLVAVPLAVLVDGRLKTSFHS---------- 76

  Fly   833 CQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFALIMALMPLV 897
            |.:...|.::.::.||::|..|.::|...:.:.:.....:..:.....::|.|:.|.|:.|:|:.
Zfish    77 CLIISCLVLVLTQASVHSLLAIAVDRYLRVYNPLRYRGAVKKQHLWIAVTVCWLSAAILGLIPMF 141

  Fly   898 GVSDYRKFAVCLPFETTTGPAS-----------LTYVISLMFINGCAF---LTLMGCYLKMYWAI 948
            |   :.|      ..|||...|           ::|:::.:|. .|..   ..:|..||.::..|
Zfish   142 G---WHK------ENTTTSENSTITCEFISVIPMSYMVNFIFF-ACLLPPTFIMMLIYLLIFTMI 196

  Fly   949 ---------RG--SQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQLISLEQAKIFT 1002
                     ||  ..::...:.::|..:||::....:||.|:...:....:...:.....|....
Zfish   197 SKQLRKGVGRGMAPNSFYQKEQKLATSLALVLVLFAVCWLPLHIMNALNYYYTNIEVPVLAFHIG 261

  Fly  1003 VFVLPLNSCCNPFLYAIMTKQFK 1025
            :.:...||..||.:||....:.:
Zfish   262 ILLSHFNSAVNPIVYAFKVPKIR 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	28/123 (23%)
		7tm_1	770..1017	CDD:278431	55/272 (20%)
LOC571410	XP_693932.2	7tm_4	22..>112	CDD:304433	24/99 (24%)
LOC571410	XP_693932.2	7tm_1	23..276	CDD:278431	55/272 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910