DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and sstr1a

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_696666.1	Gene:	sstr1a / 568254	ZFINID:	ZDB-GENE-090429-1	Length:	366	Species:	Danio rerio

Alignment Length:	302	Identity:	63/302 - (20%)
Similarity:	116/302 - (38%)	Gaps:	73/302 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   762 VVFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIP 826
            ||.|:.|.||..|::|:.............:.|||.||                   |..|.::|
Zfish    42 VVCLVGLCGNSMVIYVIFRYAKMKTATNIYILNLAIAD-------------------ELLMLSVP 87

  Fly   827 ----------WQM-SVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYI 880
                      |.. |:||:|...:..::...|:|.|.|::::|..::.|.|...:......|..:
Zfish    88 FLVTSSLLHHWPFGSLLCRLVLSVDAINMFTSIYCLTVLSIDRYISVVHPIKAARYRRPTIAKMV 152

  Fly   881 MSVGWVFALIMALMPLVGVSDYRKFAVCLPFETTTGPAS-----------------LTYVISLMF 928
            ....|:|: |:.::|::..|             ||.|.|                 :...:...|
Zfish   153 NLAVWMFS-ILVILPIIIFS-------------TTAPNSDGSVACNMQMPEPERQWMAVFVIYAF 203

  Fly   929 INGCAF--LTLMGCYLKMYWAIR------GSQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSIT 985
            :.|..|  :.:..||:.:...:|      |.|....::.:|...:.::|....:||.|.....:.
Zfish   204 LMGFLFPVIAICMCYILIIVKMRVVALKAGWQQRKKSERKITLMVMMVVTVFVICWMPFHIVQLV 268

  Fly   986 AIFGLQ-LISLEQAKIFTVFVLPLNSCCNPFLYAIMTKQFKK 1026
            ::|..| ..:|.|..:...:.   |||.||.||..::..|::
Zfish   269 SVFVQQHNATLSQLAVILGYA---NSCANPILYGFLSDNFRR 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	30/138 (22%)
		7tm_1	770..1017	CDD:278431	56/283 (20%)
sstr1a	XP_696666.1	7tm_4	42..>243	CDD:304433	46/233 (20%)
sstr1a	XP_696666.1	7tm_1	50..298	CDD:278431	56/283 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910