DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and LOC563710

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_692159.4	Gene:	LOC563710 / 563710	-ID:	-	Length:	635	Species:	Danio rerio

Alignment Length:	372	Identity:	103/372 - (27%)
Similarity:	161/372 - (43%)	Gaps:	41/372 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 ERWLQKHCHCTGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELT 209
            ||...:.|.|.|.:    :.|.......||.||......|.|..|:|..|:|..|.....|..|.
Zfish    28 ERPCPRSCRCDGKI----VYCESSAFRDVPKNLSGGCQGLSLRYNSLASLKAGQFVGLNQLIWLY 88

  Fly   210 LSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHL 274
            |..|.|.|:|..||.|:.:||.|.|.:..:..|...:|..:..|.:|.|:.|.|.:|.......|
Zfish    89 LDHNYIANVDARAFQGIRRLKELILSSNKITLLHNTTFHLVPNLRNLDLSYNKLQALQPGQFQGL 153

  Fly   275 QKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKIS 339
            :||.:|.:..|....:|:......|.||.|:||.|.|..|.......:..|..|.::.||..||:
Zfish   154 RKLLSLHMRSNSLKNLPSRLFQDCRNLEFLDLGYNRLRSITRNSMSGLLKLTELHIEHNQFSKIN 218

  Fly   340 AGALKNLTALKVLELDDNLISSLPEGLSKL-SQLQELSITSNRLRWINDTELPRSM---QMLDMR 400
            .........|:.|.|..|.|.::.|||:.: :.||:|.::.|.|:.| |.|:.|:|   |.|::.
Zfish   219 FFNFPRFYNLRALYLQWNRIRTMSEGLTWMWTSLQKLDLSGNDLQEI-DAEVYRAMPNLQTLNLD 282

  Fly   401 ANPLSTISPGAFRGMSKLRKLILSD---------------VRTLRSFPELE-ACHALEILKLDRA 449
            :|.|..:|..|....:.|..:.|:.               :||.|...|:. .|.:.:.::.::.
Zfish   283 SNKLVNVSQEAVDAWTSLTAISLAGNMWDCGPVVCPLVAWMRTFRGNKEINMICASPKEVQGEKV 347

  Fly   450 GIQEVPAN-LCR------------QTPRLKSLELKTNSLKRIPNLSS 483
             :..|.|| :||            .||.:...:...:||  :|.|.|
Zfish   348 -LDAVDANGVCRIAPATPSTIFVPSTPFVAFSQTPASSL--VPTLKS 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	5/20 (25%)
		LRR_RI	180..>383	CDD:238064	62/203 (31%)
		leucine-rich repeat	183..204	CDD:275380	7/20 (35%)
		LRR_8	203..263	CDD:290566	20/59 (34%)
		leucine-rich repeat	205..228	CDD:275380	10/22 (45%)
		leucine-rich repeat	229..252	CDD:275380	6/22 (27%)
		LRR_8	252..311	CDD:290566	19/58 (33%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	4/22 (18%)
		LRR_8	299..359	CDD:290566	19/59 (32%)
		leucine-rich repeat	301..324	CDD:275380	8/22 (36%)
		leucine-rich repeat	325..348	CDD:275380	6/22 (27%)
		LRR_RI	327..567	CDD:238064	48/190 (25%)
		leucine-rich repeat	349..371	CDD:275380	8/22 (36%)
		LRR_8	370..425	CDD:290566	18/57 (32%)
		leucine-rich repeat	372..393	CDD:275380	8/20 (40%)
		leucine-rich repeat	394..415	CDD:275380	7/23 (30%)
		leucine-rich repeat	418..486	CDD:275380	19/95 (20%)
		leucine-rich repeat	441..464	CDD:275378	6/35 (17%)
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
LOC563710	XP_692159.4	leucine-rich repeat	60..83	CDD:275380	7/22 (32%)
		LRR_RI	<81..286	CDD:238064	64/205 (31%)
		LRR_8	83..142	CDD:290566	20/58 (34%)
		leucine-rich repeat	84..107	CDD:275380	10/22 (45%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		LRR_8	130..190	CDD:290566	19/59 (32%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..179	CDD:275380	4/22 (18%)
		LRR_8	178..238	CDD:290566	19/59 (32%)
		leucine-rich repeat	180..203	CDD:275380	8/22 (36%)
		leucine-rich repeat	204..227	CDD:275380	6/22 (27%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		LRR_8	250..308	CDD:290566	18/58 (31%)
		leucine-rich repeat	252..275	CDD:275380	10/23 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910