DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and LRRC8A

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_001120716.1 Gene:LRRC8A / 56262 HGNCID:19027 Length:810 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064
leucine-rich repeat 183..204 CDD:275380
LRR_8 203..263 CDD:290566
leucine-rich repeat 205..228 CDD:275380
leucine-rich repeat 229..252 CDD:275380
LRR_8 252..311 CDD:290566
leucine-rich repeat 253..276 CDD:275380
leucine-rich repeat 277..300 CDD:275380
LRR_8 299..359 CDD:290566
leucine-rich repeat 301..324 CDD:275380
leucine-rich repeat 325..348 CDD:275380
LRR_RI 327..567 CDD:238064
leucine-rich repeat 349..371 CDD:275380
LRR_8 370..425 CDD:290566
leucine-rich repeat 372..393 CDD:275380
leucine-rich repeat 394..415 CDD:275380
leucine-rich repeat 418..486 CDD:275380
leucine-rich repeat 441..464 CDD:275378
LRR_8 487..545 CDD:290566
leucine-rich repeat 487..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
LRR_8 533..589 CDD:290566
leucine-rich repeat 535..558 CDD:275380
leucine-rich repeat 559..580 CDD:275380
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
LRRC8ANP_001120716.1 Pannexin_like 1..340 CDD:403656
internalin_A 379..>713 CDD:380193
LRR 1. /evidence=ECO:0000255 399..422
leucine-rich repeat 420..447 CDD:275380
LRR 2. /evidence=ECO:0000255 423..445
LRR 3. /evidence=ECO:0000255 447..468
leucine-rich repeat 448..470 CDD:275380
LRR 4. /evidence=ECO:0000255 469..492
leucine-rich repeat 471..494 CDD:275380
LRR 5. /evidence=ECO:0000255 493..515
leucine-rich repeat 495..517 CDD:275380
leucine-rich repeat 518..545 CDD:275380
LRR 6. /evidence=ECO:0000255 518..542
LRR 7. /evidence=ECO:0000255 543..565
leucine-rich repeat 546..568 CDD:275380
LRR 8. /evidence=ECO:0000255 567..589
LRR 568..>780 CDD:227223
leucine-rich repeat 569..592 CDD:275380
LRR 9. /evidence=ECO:0000255 590..613
leucine-rich repeat 593..615 CDD:275380
LRR 10. /evidence=ECO:0000255 615..637
leucine-rich repeat 616..640 CDD:275380
LRR 11. /evidence=ECO:0000255 639..661
leucine-rich repeat 641..663 CDD:275380
LRR 12. /evidence=ECO:0000255 662..684
leucine-rich repeat 664..686 CDD:275380
LRR 13. /evidence=ECO:0000255 686..707
leucine-rich repeat 687..709 CDD:275380
Di-leucine motif. /evidence=ECO:0000269|PubMed:33139539 706..707
LRR 14. /evidence=ECO:0000255 708..730
leucine-rich repeat 710..732 CDD:275380
LRR 15. /evidence=ECO:0000255 732..753
leucine-rich repeat 733..755 CDD:275380
LRR 16. /evidence=ECO:0000255 754..776
LRR 17. /evidence=ECO:0000255 778..801
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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