DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rk and lrit3a

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_001122166.1 Gene:lrit3a / 558559 ZFINID:ZDB-GENE-080723-63 Length:636 Species:Danio rerio


Alignment Length:370 Identity:82/370 - (22%)
Similarity:144/370 - (38%) Gaps:74/370 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 SICERWLQKHCHC--------TGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANS 198
            |:.:.:....|.|        |||..||   |....:..:|||:|.:.|.|.:....:.::...:
Zfish    15 SVAQPFCPSQCTCVYHGRSDGTGSRSVL---CNDPDMSDIPVNVPLDTVKLRVEKTAVRRVPTEA 76

  Fly   199 FFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNAL 263
            |:....|..|.::.|||.::||.:||.|..|..|.|....:.:.|.:|.:.:..|.:|.|:.|.|
Zfish    77 FYYLSELRYLWITYNSITSVDPGSFYNLKVLHELRLDGNMIATFPWESLKEMPSLKTLDLHNNRL 141

  Fly   264 VSLDGDCLGHLQKLRTLRLEGNLFYRIPTNAL------AGLRTLEALNLGSNLLTIINDEDFP-- 320
            .|:..:...:|..:..|.:..|....:|::.:      :|::.    :..::..|::..:|.|  
Zfish   142 TSVPVEAAPYLINITYLDISSNKLTTLPSDLVDIWPPFSGIQP----SANTSQKTVLGLQDNPWY 202

  Fly   321 ---RMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLS-KLSQLQELSITSNR 381
               |:..||               .|..:..:.|:.:|..|..|.||.|| .|.|..||......
Zfish   203 CDCRISKLI---------------ELSKMAGIPVVLMDQVLTCSGPEHLSGVLFQRAELDQCVKP 252

  Fly   382 LRWINDTEL--PRSMQML---DMRANPLSTI-----------------SPGAFRGMS----KLRK 420
            ....:.|::  |....:|   |....|..|:                 |||  .|:.    .|..
Zfish   253 TVMTSATKITSPLGSNVLLRCDANGFPTPTLLWTTADGSVVNNTVVQESPG--EGVRWSILSLHS 315

  Fly   421 LILSDVRTLRSFPELEACHALEILKLDRAGIQEV----PANLCRQ 461
            ::..|....|...:..|.:|...:.|...|:|..    |.|:.:|
Zfish   316 IVFKDAGDYRCKAKNVAGNAEAYITLSVDGVQPTTPFPPINITKQ 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 6/20 (30%)
LRR_RI 180..>383 CDD:238064 48/214 (22%)
leucine-rich repeat 183..204 CDD:275380 2/20 (10%)
LRR_8 203..263 CDD:290566 19/59 (32%)
leucine-rich repeat 205..228 CDD:275380 10/22 (45%)
leucine-rich repeat 229..252 CDD:275380 5/22 (23%)
LRR_8 252..311 CDD:290566 11/64 (17%)
leucine-rich repeat 253..276 CDD:275380 7/22 (32%)
leucine-rich repeat 277..300 CDD:275380 4/28 (14%)
LRR_8 299..359 CDD:290566 9/64 (14%)
leucine-rich repeat 301..324 CDD:275380 4/27 (15%)
leucine-rich repeat 325..348 CDD:275380 3/22 (14%)
LRR_RI 327..567 CDD:238064 34/166 (20%)
leucine-rich repeat 349..371 CDD:275380 9/22 (41%)
LRR_8 370..425 CDD:290566 14/80 (18%)
leucine-rich repeat 372..393 CDD:275380 4/22 (18%)
leucine-rich repeat 394..415 CDD:275380 7/40 (18%)
leucine-rich repeat 418..486 CDD:275380 11/48 (23%)
leucine-rich repeat 441..464 CDD:275378 6/25 (24%)
LRR_8 487..545 CDD:290566
leucine-rich repeat 487..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
LRR_8 533..589 CDD:290566
leucine-rich repeat 535..558 CDD:275380
leucine-rich repeat 559..580 CDD:275380
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
lrit3aNP_001122166.1 LRR_8 81..141 CDD:290566 19/59 (32%)
leucine-rich repeat 83..106 CDD:275378 10/22 (45%)
LRR_4 107..145 CDD:289563 11/37 (30%)
leucine-rich repeat 107..130 CDD:275378 5/22 (23%)
LRR_8 129..>171 CDD:290566 10/41 (24%)
LRR_4 129..170 CDD:289563 9/40 (23%)
leucine-rich repeat 131..154 CDD:275378 7/22 (32%)
leucine-rich repeat 155..168 CDD:275378 2/12 (17%)
TPKR_C2 199..249 CDD:301599 17/64 (27%)
Ig 252..343 CDD:299845 16/92 (17%)
IG_like 261..343 CDD:214653 15/83 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.