DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and adrb1

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_001122161.1 Gene:adrb1 / 557194 ZFINID:ZDB-GENE-081022-145 Length:390 Species:Danio rerio


Alignment Length:385 Identity:80/385 - (20%)
Similarity:144/385 - (37%) Gaps:90/385 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   718 GTGLFSGMSTEDFQPGSVQCLPMPGPFLPCADLFDWWTLRCGV---WVVFLLSLLGNGTVVFVLL 779
            |.||.|...:.|.:..:|.           .::.:.|.:..|:   .:||:: ::||..|:..:.
Zfish     2 GDGLPSVNYSNDSKRATVD-----------LNVSEQWLVGMGILMGLIVFVI-VVGNILVIVAIA 54

  Fly   780 CSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFR---MFAIPWQMSVLCQLSGFLAV 841
            .::....:....:.:||.||..|    |:|.:...|.| |.|   |:.     |..|:....|.|
Zfish    55 RNQRLQTLTNVFIVSLACADLIM----GLLVVPFGAAL-EVRGAWMYG-----SFFCEFWISLDV 109

  Fly   842 LSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFALIMALMPLV--------G 898
            |....|:.||.||.::|..||.........|:..:|..::...|..:.:::..|::        .
Zfish   110 LCVTASIETLCVIAIDRYIAIISPFRYQSLLTKARAKVVVCAVWAISALVSFPPILMHWSQDSEE 174

  Fly   899 VSDYRKFAVCLPFETTTGPASLTYVISLMFINGCAFLTLMGCYLKMYWAIRGSQAWN-------- 955
            .|.|.. ..|..|.|....|..:.:||...    ..:.::..|.::|  ....|..|        
Zfish   175 TSCYEN-PECCDFVTNRAYAISSSIISFYI----PLIVMIFVYARVY--REAKQQLNKINKCEGR 232

  Fly   956 ------TN---------------DSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQLISLEQAK 999
                  ||               :.:..|.:.:::.|..|||.|....::..:|..|::. ::..
Zfish   233 FYNNHGTNCKPTRKRTTKILALKEQKALKTLGIIMGTFTLCWLPFFIVNVVRVFCAQVVD-KELF 296

  Fly  1000 IFTVFVLPLNSCCNPFLYA---IMTKQFKKDCVTLC-----------KHFEESRVVGGGG 1045
            :|..::..:||..||.:|.   ...|.||:   .||           ...:.||..||.|
Zfish   297 VFLNWLGYVNSAFNPIIYCRSPDFRKAFKR---LLCCPRQADRRLHVSSCDLSRCTGGFG 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064
leucine-rich repeat 183..204 CDD:275380
LRR_8 203..263 CDD:290566
leucine-rich repeat 205..228 CDD:275380
leucine-rich repeat 229..252 CDD:275380
LRR_8 252..311 CDD:290566
leucine-rich repeat 253..276 CDD:275380
leucine-rich repeat 277..300 CDD:275380
LRR_8 299..359 CDD:290566
leucine-rich repeat 301..324 CDD:275380
leucine-rich repeat 325..348 CDD:275380
LRR_RI 327..567 CDD:238064
leucine-rich repeat 349..371 CDD:275380
LRR_8 370..425 CDD:290566
leucine-rich repeat 372..393 CDD:275380
leucine-rich repeat 394..415 CDD:275380
leucine-rich repeat 418..486 CDD:275380
leucine-rich repeat 441..464 CDD:275378
LRR_8 487..545 CDD:290566
leucine-rich repeat 487..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
LRR_8 533..589 CDD:290566
leucine-rich repeat 535..558 CDD:275380
leucine-rich repeat 559..580 CDD:275380
7tm_4 764..>892 CDD:304433 32/130 (25%)
7tm_1 770..1017 CDD:278431 59/286 (21%)
adrb1NP_001122161.1 7tm_4 40..328 CDD:304433 64/309 (21%)
7tm_1 45..314 CDD:278431 59/286 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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