DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and Sstr2

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_062221.1	Gene:	Sstr2 / 54305	RGDID:	3763	Length:	369	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	74/331 - (22%)
Similarity:	143/331 - (43%)	Gaps:	41/331 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   725 MSTEDFQPGSVQCLPMP-------GP------FLPCADLFDWWTLRCGVWVVFLLSLLGNGTVVF 776
            :::|.|. ||...:|.|       ||      ..|..|:.....|....:||.::.|.||..|::
  Rat     3 LTSEQFN-GSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIY 66

  Fly   777 VLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIPWQM-SVLCQLSGFLA 840
            |:|.......:....:.|||.||....:.|..||:         ::..:.|.. ..:|::...:.
  Rat    67 VILRYAKMKTITNIYILNLAIADELFMLGLPFLAM---------QVALVHWPFGKAICRVVMTVD 122

  Fly   841 VLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFAL--IMALMPLVGV--SD 901
            .::...|::.|.|::::|..|:.|.|...|....:.|..|....|..:|  |:.:|...|:  :.
  Rat   123 GINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQ 187

  Fly   902 YRKFAVCLPFETTTGPASLTYVISLMFINGCAFLTLMG-CYLKMYWAIR------GSQAWNTNDS 959
            :.:.:..:.:...:|.....::|....:.....||::. |||.:...::      ||.....::.
  Rat   188 WGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEK 252

  Fly   960 RIAKRMALLVFTDFLCWSPIAFFSITAIFGLQLIS----LEQAKIFTVFVLPLNSCCNPFLYAIM 1020
            ::.:.::::|.....||.|...|:::::  ...||    |:....|.|.:...|||.||.|||.:
  Rat   253 KVTRMVSIVVAVFIFCWLPFYIFNVSSV--SVAISPTPALKGMFDFVVILTYANSCANPILYAFL 315

  Fly  1021 TKQFKK 1026
            :..|||
  Rat   316 SDNFKK 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	29/130 (22%)
		7tm_1	770..1017	CDD:278431	54/262 (21%)
Sstr2	NP_062221.1	7tm_4	54..327	CDD:304433	61/279 (22%)
Sstr2	NP_062221.1	7tm_1	60..312	CDD:278431	54/262 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910