DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and Cxcr1

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_062183.1	Gene:	Cxcr1 / 54258	RGDID:	2905	Length:	349	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	91/356 - (25%)
Similarity:	144/356 - (40%)	Gaps:	81/356 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   728 EDFQPGSV-QCLPMPGPFLPCADLFDWWTLRCGVWV----VFLLSLLGNGTVVFVLLCSRSKMDV 787
            |:|  |:: :.||....|.||..:  ..|.|..|.|    |||||||||..|:.|:|..|....|
  Rat    18 EEF--GNITRMLPTGEYFSPCKRV--PMTNRQAVVVFYALVFLLSLLGNSLVMLVILYRRRTRSV 78

  Fly   788 PRFLVCNLAAADFFMGIYLGILAIVDAATLGEFR--MFAIPWQMSVLCQLSGFLAVLSSELSVYT 850
            ....|.|||.||....:.|..||:      .:::  :|..|     ||::...|..::....:..
  Rat    79 TDVYVLNLAIADLLFSLTLPFLAV------SKWKGWIFGTP-----LCKMVSLLKEVNFFSGILL 132

  Fly   851 LAVITLERNYAITHAIH--LNKRLSLKQAGYIMSVGWVFALIMALMPLV----GVSDYRKFAVCL 909
            ||.|:::|..||.||..  ..||..:|   ::....|..:|:::| |..    ....||...||
  Rat   133 LACISVDRYLAIVHATRTLTRKRYLVK---FVCMGTWGLSLVLSL-PFAIFRQAYKPYRSGTVC- 192

  Fly   910 PFET---TTGPASLT---------YVISLMFINGCAFLTLMGCY-------LKMYWAIRGSQAWN 955
             :|.   .|....:|         :::.|..:..|..|||...:       .:..|.|..
  Rat   193 -YEVLGEATADLRITLRGLSHIFGFLLPLFIMLVCYGLTLRTLFKAHMRQKRRAMWVIFA----- 251

  Fly   956 TNDSRIAKRMALLVFTDFLCWSP--IAFFSITAIFGLQLI--------SLEQAKIFTVFVLPLNS 1010
                      .:|||  .||..|  :...|.| :.|..||        :::||...|..:...:|
  Rat   252 ----------VVLVF--LLCCLPYNLVLLSDT-LLGAHLIQDTCERRNNIDQALYITEILGFSHS 303

  Fly  1011 CCNPFLYAIMTKQFKKDCVTLCKHFEESRVV 1041
            |.||.:||.:.:.|:.:.:.:..:.....|:
  Rat   304 CLNPVIYAFVGQSFRHEFLKILANLVHKEVL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	40/131 (31%)
		7tm_1	770..1017	CDD:278431	68/283 (24%)
Cxcr1	NP_062183.1	7tm_1	61..310	CDD:278431	68/283 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910