DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and lrfn1

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_956909.1 Gene:lrfn1 / 393587 ZFINID:ZDB-GENE-040426-1227 Length:584 Species:Danio rerio


Alignment Length:308 Identity:85/308 - (27%)
Similarity:128/308 - (41%) Gaps:57/308 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 CHCTGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSII 216
            |.|......|.|.|...|:|.||..:..:.|.|.|.:|.:|.:....|....:|..||||.|:|.
Zfish    24 CICQTISPTLTLLCAKTGLLFVPPTVDRKTVELRLTDNFITAVRRKDFLNMTSLVHLTLSRNTIS 88

  Fly   217 NMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLR 281
            .:.|:||.||..|:                        :|.::||.|..::.|.|..|..||.|.
Zfish    89 QIAPHAFMGLKSLR------------------------ALHMDGNRLSVINSDQLKGLMNLRHLI 129

  Fly   282 LEGNLFYRIPTNAL-AGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKN 345
            |..|..:.|..::. ..:.|:|.|:|..|.|..:..|...||.|:..|.|..|.|..|..|....
Zfish   130 LGNNQIHHIEESSFDEFVATIEDLDLSYNNLRTLPWEAIARMTNINTLTLDHNLIDHIGVGTFTL 194

  Fly   346 LTALKVLELDDNLISSL-PEGLSKLSQL--QELSITSNRLRWINDTELPRSMQMLDMRANPLSTI 407
            ||.|..|::..|.:.:| |:.|.:.:|:  :..:.:|:||             .:....|||...
Zfish   195 LTKLVRLDMTSNRLQTLPPDTLFQHAQVLSEPKTSSSSRL-------------TVSFGGNPLHCN 246

  Fly   408 SPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRA--GIQE 453
            ..     :..||:|...|        :||.|.:.|.| :|:.  .|||
Zfish   247 CE-----LLWLRRLTRED--------DLETCASPEHL-MDKYFWSIQE 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 7/20 (35%)
LRR_RI 180..>383 CDD:238064 59/206 (29%)
leucine-rich repeat 183..204 CDD:275380 5/20 (25%)
LRR_8 203..263 CDD:290566 16/59 (27%)
leucine-rich repeat 205..228 CDD:275380 12/22 (55%)
leucine-rich repeat 229..252 CDD:275380 1/22 (5%)
LRR_8 252..311 CDD:290566 18/59 (31%)
leucine-rich repeat 253..276 CDD:275380 7/22 (32%)
leucine-rich repeat 277..300 CDD:275380 6/23 (26%)
LRR_8 299..359 CDD:290566 21/59 (36%)
leucine-rich repeat 301..324 CDD:275380 8/22 (36%)
leucine-rich repeat 325..348 CDD:275380 7/22 (32%)
LRR_RI 327..567 CDD:238064 34/132 (26%)
leucine-rich repeat 349..371 CDD:275380 6/22 (27%)
LRR_8 370..425 CDD:290566 10/56 (18%)
leucine-rich repeat 372..393 CDD:275380 3/22 (14%)
leucine-rich repeat 394..415 CDD:275380 3/20 (15%)
leucine-rich repeat 418..486 CDD:275380 13/38 (34%)
leucine-rich repeat 441..464 CDD:275378 6/15 (40%)
LRR_8 487..545 CDD:290566
leucine-rich repeat 487..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
LRR_8 533..589 CDD:290566
leucine-rich repeat 535..558 CDD:275380
leucine-rich repeat 559..580 CDD:275380
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
lrfn1NP_956909.1 LRR 1 52..73 6/20 (30%)
LRR_8 55..111 CDD:290566 21/79 (27%)
leucine-rich repeat 55..76 CDD:275380 5/20 (25%)
LRR_RI <71..>208 CDD:238064 48/160 (30%)
LRR 2 76..97 10/20 (50%)
leucine-rich repeat 77..100 CDD:275380 12/22 (55%)
LRR_8 99..160 CDD:290566 19/84 (23%)
LRR 3 100..121 7/44 (16%)
leucine-rich repeat 101..124 CDD:275380 8/46 (17%)
LRR 4 124..145 6/20 (30%)
leucine-rich repeat 125..148 CDD:275380 6/22 (27%)
LRR 5 149..170 7/20 (35%)
leucine-rich repeat 150..173 CDD:275380 8/22 (36%)
LRR_8 153..208 CDD:290566 19/54 (35%)
LRR 6 173..194 7/20 (35%)
leucine-rich repeat 174..197 CDD:275380 7/22 (32%)
LRR 7 197..218 6/20 (30%)
leucine-rich repeat 198..222 CDD:275380 6/23 (26%)
LRRCT 241..>270 CDD:214507 11/41 (27%)
IG_like 299..375 CDD:214653
Ig_2 303..376 CDD:143241
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 393..414
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 539..564
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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