DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and tsku

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_956027.2 Gene:tsku / 325958 ZFINID:ZDB-GENE-030131-4683 Length:366 Species:Danio rerio


Alignment Length:345 Identity:94/345 - (27%)
Similarity:142/345 - (41%) Gaps:73/345 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   150 KHCH----CT-------GSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAP 203
            |:||    |.       .|..:.::.|..||....||.:|.:...|||..|::|.: :::....|
Zfish    40 KNCHPQCRCEVETFGLFDSFSLTKVDCSRIGPGNTPVPIPLDTSHLDLSLNSITSI-SDTMLSGP 103

  Fly   204 ---NLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVS 265
               .|..|.||.|.|..:.|.||..|..|:.|.|.:..|:.|....|.|| .|..|.|:.|....
Zfish   104 GYTTLVSLDLSSNLIAQISPKAFSKLRYLETLDLSSNALEGLSDGCFTGL-PLVELDLSENQFKE 167

  Fly   266 LDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPN----LI 326
            .:.|       |.|.|.:.     :|.          .::|..||||.|    |.|.|.    :.
Zfish   168 FNLD-------LFTTRTQD-----LPI----------MVDLSRNLLTSI----FRRTPGHPLYIK 206

  Fly   327 VLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEG-LSKLSQLQELSITSNRLRWINDTEL 390
            .|:|..||:..:..   .|...|:.|.||.|||||:..| ...|::|..||::.           
Zfish   207 SLMLAGNQLKTVPK---LNGIPLQYLNLDGNLISSIDTGAFDSLTELVHLSLSG----------- 257

  Fly   391 PRSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSF-PEL-EACHALEILKLDRAGIQE 453
                      .:.|:.|.|||||.:..|:.|.||:...|::. |:: ....:|:.|.|....:..
Zfish   258 ----------LSELTLIHPGAFRSLKNLQALDLSNNSQLKTLNPDVFSGLVSLQELNLSNTAVTP 312

  Fly   454 VPANLCRQTPRLKSLELKTN 473
            :...:..|.|.:||:.|..|
Zfish   313 LSRTVFMQMPNIKSITLGPN 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 5/20 (25%)
LRR_RI 180..>383 CDD:238064 61/210 (29%)
leucine-rich repeat 183..204 CDD:275380 6/23 (26%)
LRR_8 203..263 CDD:290566 23/62 (37%)
leucine-rich repeat 205..228 CDD:275380 10/22 (45%)
leucine-rich repeat 229..252 CDD:275380 8/22 (36%)
LRR_8 252..311 CDD:290566 11/58 (19%)
leucine-rich repeat 253..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..300 CDD:275380 4/22 (18%)
LRR_8 299..359 CDD:290566 19/63 (30%)
leucine-rich repeat 301..324 CDD:275380 8/22 (36%)
leucine-rich repeat 325..348 CDD:275380 5/22 (23%)
LRR_RI 327..567 CDD:238064 41/150 (27%)
leucine-rich repeat 349..371 CDD:275380 11/22 (50%)
LRR_8 370..425 CDD:290566 13/54 (24%)
leucine-rich repeat 372..393 CDD:275380 3/20 (15%)
leucine-rich repeat 394..415 CDD:275380 7/20 (35%)
leucine-rich repeat 418..486 CDD:275380 15/58 (26%)
leucine-rich repeat 441..464 CDD:275378 4/22 (18%)
LRR_8 487..545 CDD:290566
leucine-rich repeat 487..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
LRR_8 533..589 CDD:290566
leucine-rich repeat 535..558 CDD:275380
leucine-rich repeat 559..580 CDD:275380
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
tskuNP_956027.2 leucine-rich repeat 82..107 CDD:275380 6/25 (24%)
LRR_8 106..165 CDD:290566 22/59 (37%)
LRR_RI 108..311 CDD:238064 71/253 (28%)
leucine-rich repeat 108..131 CDD:275380 10/22 (45%)
leucine-rich repeat 132..153 CDD:275380 6/20 (30%)
leucine-rich repeat 155..176 CDD:275380 7/27 (26%)
leucine-rich repeat 177..220 CDD:275380 14/61 (23%)
LRR_8 206..257 CDD:290566 19/53 (36%)
leucine-rich repeat 226..249 CDD:275380 11/22 (50%)
LRR_8 248..308 CDD:290566 19/80 (24%)
leucine-rich repeat 250..274 CDD:275380 10/44 (23%)
leucine-rich repeat 275..299 CDD:275380 6/23 (26%)
leucine-rich repeat 300..323 CDD:275380 4/22 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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