DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rk and Rrh

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_006232065.1	Gene:	Rrh / 310869	RGDID:	1308948	Length:	337	Species:	Rattus norvegicus

Alignment Length:	344	Identity:	74/344 - (21%)
Similarity:	131/344 - (38%)	Gaps:	77/344 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   762 VVFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAI- 825
            |..::|:|.|..|:.:.:..:........::.|||..|      :|:.:|       .:.|.|.
  Rat    34 VAGIISILSNIIVLGIFIKYKELRTPTNAVIINLAFTD------IGVSSI-------GYPMSAAS 85

  Fly   826 ----PWQMS-VLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSV-- 883
                .|:.. ..||:...|.:....:|:..|.|:.|:| |.......:.:|::...  |:..|
  Rat    86 DLHGSWKFGHAGCQVYAGLNIFFGMVSIGLLTVVALDR-YLTISCPDVGRRMTGNT--YLSMVLG 147

  Fly   884 GWVFALIMALMPLVGVSDYR---KFAVCLPFETTTGPASLTYVISLMFINGCAFLTLM-GCYLKM 944
            .|:..|..||||:||.:.|.   ..|.|.........:.::|.:.::.:|....||:| .||..:
  Rat   148 AWINGLFWALMPIVGWASYAPDPTGATCTINWRKNDTSFVSYTMMVIVVNFIVPLTVMFYCYYHV 212

  Fly   945 YWAIRGSQAWN---------TNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFG--------LQL 992
            ..::|.|.|.|         .:.:.:.|...:::....|.|||.:...:.|.||        |.:
  Rat   213 SQSMRLSAASNCTTHLNRDWAHQADVTKMSVMMILMFLLAWSPYSVVCLWACFGNPKKIPPSLAI 277

  Fly   993 ISLEQAKIFTVFVLPLNSCCNPFLYAIMTKQFKKDCVTL--CKHFEESRVVGGGGPGGRGAVART 1055
            |:...||..|.:        ||.:|....|:|:|....:  |:..:.
  Rat   278 IAPLFAKSSTFY--------NPCIYVAANKKFRKAMFAMLKCQPHQA------------------ 316

  Fly  1056 KRGDLPPPLLPAAAVAHPP 1074
                :|.|...|..|.|.|
  Rat   317 ----MPEPSTLAMGVPHSP 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	27/135 (20%)
		7tm_1	770..1017	CDD:278431	60/275 (22%)
Rrh	XP_006232065.1	7tm_1	43..294	CDD:278431	60/274 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910