DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and Dnaaf11

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_038934705.1	Gene:	Dnaaf11 / 299920	RGDID:	1559937	Length:	486	Species:	Rattus norvegicus

Alignment Length:	184	Identity:	49/184 - (26%)
Similarity:	75/184 - (40%)	Gaps:	40/184 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 FRGMSKLRKLILSDVRTLRSFPELEACH------ALEILKLDRAGIQEVP--ANLCRQTPRLKSL 468
            ||.:..::.|:|.:|..........|.|      :||.|.|.:..|:.:.  ...||.   ||.|
  Rat     2 FRSLPNVQGLLLVNVGVTEDLIRRNAEHNECVIFSLEELSLHQQEIERLEHIDKWCRD---LKIL 63

  Fly   469 ELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYN------RIKAL--- 524
            .|:.|.:.:|.|:|..:.|..|:|:.|.||:|:.  ..|.:.|..|.|:.|      .||.|
  Rat    64 YLQNNLIAKIENVSKLKKLEYLNLALNNIERIEN--LEGCEWLTKLDLTVNFIGELSSIKTLTHN 126

  Fly   525 -----------PQDAFQG------IPKLQLLDLEGNEISYIHK-EAFSGFTALE 560
                       |...|.|      :...||..|:|.||....: :|...:.|:|
  Rat   127 IHLRELFLVGNPCADFDGYREFVVVTLQQLKWLDGKEIERSERIQALQNYAAVE 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064	49/184 (27%)
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566	4/12 (33%)
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380	2/2 (100%)
		leucine-rich repeat	418..486	CDD:275380	20/75 (27%)
		leucine-rich repeat	441..464	CDD:275378	7/24 (29%)
		LRR_8	487..545	CDD:290566	22/83 (27%)
		leucine-rich repeat	487..510	CDD:275380	8/22 (36%)
		leucine-rich repeat	511..534	CDD:275380	10/48 (21%)
		LRR_8	533..589	CDD:290566	9/29 (31%)
		leucine-rich repeat	535..558	CDD:275380	7/23 (30%)
		leucine-rich repeat	559..580	CDD:275380	1/2 (50%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
Dnaaf11	XP_038934705.1	leucine-rich repeat	8..35	CDD:275378	5/26 (19%)
		PPP1R42	<37..179	CDD:411060	40/146 (27%)
		leucine-rich repeat	37..59	CDD:275378	6/21 (29%)
		leucine-rich repeat	60..81	CDD:275378	8/20 (40%)
		leucine-rich repeat	82..103	CDD:275378	8/22 (36%)
		leucine-rich repeat	104..128	CDD:275378	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910