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Protein Alignment rk and P2RY8

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_006724506.2	Gene:	P2RY8 / 286530	HGNCID:	15524	Length:	548	Species:	Homo sapiens

Alignment Length:	512	Identity:	103/512 - (20%)
Similarity:	176/512 - (34%)	Gaps:	140/512 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   557 TALEDLNLGNNIFPELPESGLRALLHLKTFNNPKLREFPPPDTFPRIQTLILSYAYHCCAFLPL- 620
            :.|.|..|....:|  |||  |||.|.:......|....|..:...:..|:|...:....||..
Human    76 STLSDHGLQAGGWP--PES--RALRHGRRLKRCILLPGDPLSSHLLLLPLLLHRQFSAQKFLDSH 136

  Fly   621 VAMSSQKKTSQVQEAVLFPS---------DAEFDMTLWNNSMMNIWPQMHNLSKQLGASMHDPWE 676
            :......|.::..:.:.|||         .|...:....:     |.|:.:..:       ||
Human   137 LCRPDTAKNNRCADFLKFPSCPLSPGGAQTASLCLLCQGS-----WHQLESPGE-------DP-- 187

  Fly   677 TAINFNEEQLQTQTGGQIATSYMEEYFEEHDVSGPATGYGFGTGLFSGMSTEDFQPGSVQCLPMP 741
                 :..|:...||...||..|        :..||....... ::|          .|..:.:|
Human   188 -----SRMQVPNSTGPDNATLQM--------LRNPAIAVALPV-VYS----------LVAAVSIP 228

  Fly   742 GPFLPCADLFDWWTL--RCG---VWVVFLLSLLGNGTVVFVLL-------CSRSKMDVPRFLVCN 794
            |      :||..|.|  |.|   ..|:|:::|.....::..:|       |:|... |...|:||
Human   229 G------NLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHW-VFGVLLCN 286

  Fly   795 LAAADFFMGIYLGILAIVDAATLGEFRMFAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERN 859
            :....|:..:|..||                                        |:..|::||.
Human   287 VVTVAFYANMYSSIL----------------------------------------TMTCISVERF 311

  Fly   860 YAITHAIHLNKRLSLKQAGYIMSVGWVFALIMALMPL-----------VGV---SDYRKFAVCLP 910
            ..:.:.:. :||...::.......|....|:.||.||           :|:   .|..|:.: ||
Human   312 LGVLYPLS-SKRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTM-LP 374

  Fly   911 FETTTGPASLTYVISLMFINGCAFLTLMGCY----LKMYWAIRGSQAWNTNDSRIAKRMALLVFT 971
            ..........|..|.|..|   .|:..:.||    ||:   :|..:|......|.|..:|.:|..
Human   375 SVAMWAVFLFTIFILLFLI---PFVITVACYTATILKL---LRTEEAHGREQRRRAVGLAAVVLL 433

  Fly   972 DFL-CWSPIAFFSITAIFGLQLISLEQAKIF--TVFVLPLNSCCNPFLYAIMTKQFK 1025
            .|: |::|..|..:..|............::  |:.:..||:|.:||:|...:::|:
Human   434 AFVTCFAPNNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQ 490

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.