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Protein Alignment rk and Lrrc8a

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_808393.1	Gene:	Lrrc8a / 241296	MGIID:	2652847	Length:	810	Species:	Mus musculus

Alignment Length:	449	Identity:	124/449 - (27%)
Similarity:	197/449 - (43%)	Gaps:	76/449 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 VVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNS---------IINMDPNAFYGLAKLKRLSLQN 236
            |.:.::..|.|.:|..|:.:....|.: .|:.|:         :::..|:..:.|.:|:.|.|:.
Mouse   392 VFLSEVSENKLRQLNLNNEWTLDKLRQ-RLTKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLEL 455

  Fly   237 CGLKSLPPQSFQGLAQLTSLQ---LNGNALVSLDGDCLGHL-QKLRTLRLEGNLFYRIPTNALAG 297
            ....::||    .:||||.|:   |...| ..::...|..| :.||.|.::......||. .:..
Mouse   456 IPDVTIPP----SIAQLTGLKELWLYHTA-AKIEAPALAFLRENLRALHIKFTDIKEIPL-WIYS 514

  Fly   298 LRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSL 362
            |:|||.|:|..||..                  :.|:.:.|.  .|:.|..||||.|..|| |.|
Mouse   515 LKTLEELHLTGNLSA------------------ENNRYIVID--GLRELKRLKVLRLKSNL-SKL 558

  Fly   363 PEGLSKLS-QLQELSITS--------NRL-RWINDTELPRSMQMLDMRANPLSTISPGAFRGMSK 417
            |:.::.:. .||:|||.:        |.| :.:|.|||  .:...|:...|.|..|      :..
Mouse   559 PQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTEL--ELIRCDLERIPHSIFS------LHN 615

  Fly   418 LRKLILSD--VRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIP- 479
            |:::.|.|  ::|:......:..|.|..|||....|..:|..:...| .|:.|.|..|.:::||
Mouse   616 LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLT-NLERLYLNRNKIEKIPT 679

  Fly   480 NLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNE 544
            .|..||.||.||||.|.:..:.. ....|:.|.:|.::.|||:|||.:.|| ..||:.|.| ||.
Mouse   680 QLFYCRKLRYLDLSHNNLTFLPA-DIGLLQNLQNLAVTANRIEALPPELFQ-CRKLRALHL-GNN 741

  Fly   545 ISYIHKEAFSGFTALEDLNL-GNNI---------FPELPESGLRALLHLKTFNNPKLRE 593
            :...........|.|..:.| ||.:         .|.|..|||.....|.:...|:::|
Mouse   742 VLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKE 800

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.