| Sequence 1: | NP_476702.1 | Gene: | rk / 34819 | FlyBaseID: | FBgn0003255 | Length: | 1360 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001127948.1 | Gene: | LRRC8B / 23507 | HGNCID: | 30692 | Length: | 803 | Species: | Homo sapiens |
| Alignment Length: | 597 | Identity: | 147/597 - (24%) |
|---|---|---|---|
| Similarity: | 216/597 - (36%) | Gaps: | 172/597 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 35 DETKENPAPDMQNSQEQEPYVHLQHLQQQQQQNPQTVQQLSQITVNRTSKSASVTPTGIRENVML 99
Fly 100 PSADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLS 164
Fly 165 CRGIGILAVPVNLPNEVVVLDLGNNNLTKLEA--NSF--------FMAPNLEELTLSDNSIINMD 219
Fly 220 PNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEG 284
Fly 285 NLFYRIP---TNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNL 346
Fly 347 TALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPRSMQMLDMRANPLSTISPGA 411
Fly 412 FRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLK 476
Fly 477 RIP-NLSSCRDLRLLDLSSNQI----EKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQ 536
Fly 537 LLDLEGNEISYI--HKEAFSGFTALEDLNLGN---NIFPELPESGLRAL-LHLKTFNNPKLREFP 595
Fly 596 PPDTFPRIQTLI 607 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| rk | NP_476702.1 | leucine-rich repeat | 158..179 | CDD:275380 | 7/20 (35%) |
| LRR_RI | 180..>383 | CDD:238064 | 55/215 (26%) | ||
| leucine-rich repeat | 183..204 | CDD:275380 | 6/30 (20%) | ||
| LRR_8 | 203..263 | CDD:290566 | 18/59 (31%) | ||
| leucine-rich repeat | 205..228 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 229..252 | CDD:275380 | 7/22 (32%) | ||
| LRR_8 | 252..311 | CDD:290566 | 22/61 (36%) | ||
| leucine-rich repeat | 253..276 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 277..300 | CDD:275380 | 12/25 (48%) | ||
| LRR_8 | 299..359 | CDD:290566 | 13/59 (22%) | ||
| leucine-rich repeat | 301..324 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 325..348 | CDD:275380 | 2/22 (9%) | ||
| LRR_RI | 327..567 | CDD:238064 | 65/249 (26%) | ||
| leucine-rich repeat | 349..371 | CDD:275380 | 7/21 (33%) | ||
| LRR_8 | 370..425 | CDD:290566 | 8/54 (15%) | ||
| leucine-rich repeat | 372..393 | CDD:275380 | 2/20 (10%) | ||
| leucine-rich repeat | 394..415 | CDD:275380 | 6/20 (30%) | ||
| leucine-rich repeat | 418..486 | CDD:275380 | 18/68 (26%) | ||
| leucine-rich repeat | 441..464 | CDD:275378 | 7/22 (32%) | ||
| LRR_8 | 487..545 | CDD:290566 | 23/61 (38%) | ||
| leucine-rich repeat | 487..510 | CDD:275380 | 10/26 (38%) | ||
| leucine-rich repeat | 511..534 | CDD:275380 | 7/22 (32%) | ||
| LRR_8 | 533..589 | CDD:290566 | 18/61 (30%) | ||
| leucine-rich repeat | 535..558 | CDD:275380 | 7/24 (29%) | ||
| leucine-rich repeat | 559..580 | CDD:275380 | 8/23 (35%) | ||
| 7tm_4 | 764..>892 | CDD:304433 | |||
| 7tm_1 | 770..1017 | CDD:278431 | |||
| LRRC8B | NP_001127948.1 | Pannexin_like | 1..334 | CDD:315247 | |
| PLN00113 | <428..>704 | CDD:215061 | 98/384 (26%) | ||
| LRR 1 | 464..486 | 5/21 (24%) | |||
| leucine-rich repeat | 465..488 | CDD:275380 | 4/22 (18%) | ||
| LRR 2 | 488..509 | 5/21 (24%) | |||
| leucine-rich repeat | 489..511 | CDD:275380 | 5/22 (23%) | ||
| LRR 3 | 511..532 | 10/30 (33%) | |||
| leucine-rich repeat | 512..539 | CDD:275380 | 13/46 (28%) | ||
| LRR 4 | 539..559 | 10/20 (50%) | |||
| leucine-rich repeat | 540..562 | CDD:275380 | 11/22 (50%) | ||
| LRR 5 | 562..582 | 7/46 (15%) | |||
| leucine-rich repeat | 563..609 | CDD:275380 | 16/72 (22%) | ||
| LRR | <578..788 | CDD:227223 | 72/291 (25%) | ||
| LRR 6 | 586..607 | 6/20 (30%) | |||
| LRR 7 | 609..630 | 10/61 (16%) | |||
| leucine-rich repeat | 610..634 | CDD:275380 | 12/67 (18%) | ||
| LRR 8 | 634..655 | 7/21 (33%) | |||
| leucine-rich repeat | 635..657 | CDD:275380 | 7/22 (32%) | ||
| LRR 9 | 657..678 | 6/20 (30%) | |||
| leucine-rich repeat | 658..680 | CDD:275380 | 7/21 (33%) | ||
| LRR 10 | 680..701 | 9/25 (36%) | |||
| leucine-rich repeat | 681..703 | CDD:275380 | 10/26 (38%) | ||
| LRR 11 | 703..724 | 7/21 (33%) | |||
| leucine-rich repeat | 704..726 | CDD:275380 | 7/22 (32%) | ||
| LRR 12 | 726..747 | 7/20 (35%) | |||
| leucine-rich repeat | 727..749 | CDD:275380 | 6/21 (29%) | ||
| LRR 13 | 749..771 | 9/25 (36%) | |||
| leucine-rich repeat | 750..772 | CDD:275380 | 9/25 (36%) | ||
| leucine-rich repeat | 773..796 | CDD:275380 | 5/23 (22%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||