DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and Opn4

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_620215.1	Gene:	Opn4 / 192223	RGDID:	621701	Length:	474	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	77/324 - (23%)
Similarity:	130/324 - (40%)	Gaps:	41/324 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   735 VQCLPM----PG-------PFLPCADLFD--WWTLRCGVWVVFLLSLLGNGTVVFVLLCSRSKMD 786
            ||.|.:    ||       || |..|:.|  .:||...:.:|.|..:|||.||::....:|....
  Rat    40 VQLLSVSPTTPGLQAAAWVPF-PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRT 103

  Fly   787 VPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIPWQMSVLCQLSGFLAVLSSELSVYTL 851
            ....|:.|||.:||.|.....  .:..|::|.:..:|.     ...|:...|...:...:|:.||
  Rat   104 PANMLIINLAVSDFLMSFTQA--PVFFASSLYKKWLFG-----ETGCKFYAFCGAVFGIVSMITL 161

  Fly   852 AVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFALIMALMPLVGVSDY---RKFAVCLPFET 913
            ..|.::|...||..:......|.::...::...|::||..:|.|..|.|.|   .....|.....
  Rat   162 TAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYV 226

  Fly   914 TTGPASLTYVISLM-FINGCAFLTLMGCYLKMYWAIR--GSQAWNTNDSRIAKR----------- 964
            |..|....|.:.|. |:.....|.::.||:.::.|||  |.......:|.:.:|
  Rat   227 TFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKM 291

  Fly   965 --MALLVFTDF-LCWSPIAFFSITAIFGLQLISLEQAKIFTVFVLPLNSCCNPFLYAIMTKQFK 1025
              :||:|...| |.|:|.:..::....|...|...........:...::..||.:|||...:::
  Rat   292 AKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	30/127 (24%)
		7tm_1	770..1017	CDD:278431	59/266 (22%)
Opn4	NP_620215.1	7tm_4	78..>245	CDD:304433	42/173 (24%)
		7tm_1	87..347	CDD:278431	59/266 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..474
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910