DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and T05H4.3

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_001343670.1 Gene:T05H4.3 / 188149 WormBaseID:WBGene00020266 Length:1150 Species:Caenorhabditis elegans


Alignment Length:519 Identity:122/519 - (23%)
Similarity:206/519 - (39%) Gaps:103/519 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   250 LAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALN----LGSNL 310
            :.:||:|:|....|..|.|     :|:|.:|:     |..:..|.|..|:.|..|.    |.::.
 Worm   626 MTRLTALELCDQKLTKLTG-----IQELVSLQ-----FLSVRKNKLTSLKKLNRLPCLKLLDASF 680

  Fly   311 LTIINDEDFPRMPNLIVLLLKRNQIMKI----SAGALKNLTALKVLELDDNLISSLPEGLSKLSQ 371
            ..|...|..|  .:|:.:.|..|::..:    |.|..::|.      |..|.|.|: :|:....|
 Worm   681 NHISKIEQLP--SSLLHVDLSHNKLQTLVFCQSLGNTRHLL------LHRNQIKSM-KGVESCVQ 736

  Fly   372 LQELSITSNRLRWINDTELPRSMQM---LDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFP 433
            |:...:..|.|:..:|.||.::|..   |||..|.||:......|.|...:.||..|    |...
 Worm   737 LETFFVNDNLLKDKSDVELLKTMPKLTHLDMSNNILSSAEGYRPRVMQAAQFLISLD----RQII 797

  Fly   434 ELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRI----PNLSSCRDLRLLDLSS 494
            .||..|...:.:..|....|:...:|.:....|.|.:....:::|    ..:.....:||:|||.
 Worm   798 PLEERHVNTMKQTTRGLSLELIERICPEWKNKKELMICDQKIEQIILEKSQMEELSQIRLIDLSK 862

  Fly   495 NQIEKIQG-KPFNGLKQLNDLLLSYNRIKALP----QDAFQGIPKLQLLDLEGNEIS-------- 546
            |::..::. ..||    :..|:|:.|.:|::.    |.:.|..|.|:.||:..|.||        
 Worm   863 NRLSSVREISSFN----ITHLILNNNCLKSIAVNDGQTSLQPFPYLENLDISNNSISNTSILRLG 923

  Fly   547 ----------YIHKEAFSGFTA-------LEDLNLGNNIFPELPESGLRALLHLKTFNNPKLREF 594
                      .:.:.|.|.|..       ||.::|.||....:....|:.|..|...|| ||...
 Worm   924 IPLLLKLKNINLSQNALSRFDCSLFDLPNLESVDLSNNSIKTIIRRPLKTLTSLNLQNN-KLTTL 987

  Fly   595 PPPDTFPRIQTLILS--YAYHCCAFLPLVAMSSQK----KTSQVQEAVLF--------PSDAEFD 645
            .|. :.|.:.:|.:|  ....|.:..||....:.:    :.:.|.|..::        ||..:.|
 Worm   988 TPL-SCPNLVSLDISNNKLASCASLKPLCECKTLENLDCRNNSVTERRVYVDFIKAQVPSVRKLD 1051

  Fly   646 MTLWNN---------SMMNIWPQMHNLSKQLGASMHDPWETAINFNEEQLQTQTGGQIATSYME 700
            ..:.:|         |..|....|...|..:.:||.. |     |..|:.:|....:.|:|::|
 Worm  1052 DEIMSNEIEITKRRLSRANDLISMSRRSSMVTSSMLS-W-----FEREEGETLENVKRASSFLE 1109

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064 34/140 (24%)
leucine-rich repeat 183..204 CDD:275380
LRR_8 203..263 CDD:290566 4/12 (33%)
leucine-rich repeat 205..228 CDD:275380
leucine-rich repeat 229..252 CDD:275380 0/1 (0%)
LRR_8 252..311 CDD:290566 17/62 (27%)
leucine-rich repeat 253..276 CDD:275380 7/22 (32%)
leucine-rich repeat 277..300 CDD:275380 6/22 (27%)
LRR_8 299..359 CDD:290566 14/67 (21%)
leucine-rich repeat 301..324 CDD:275380 6/26 (23%)
leucine-rich repeat 325..348 CDD:275380 6/26 (23%)
LRR_RI 327..567 CDD:238064 66/280 (24%)
leucine-rich repeat 349..371 CDD:275380 5/21 (24%)
LRR_8 370..425 CDD:290566 18/57 (32%)
leucine-rich repeat 372..393 CDD:275380 6/20 (30%)
leucine-rich repeat 394..415 CDD:275380 8/23 (35%)
leucine-rich repeat 418..486 CDD:275380 13/71 (18%)
leucine-rich repeat 441..464 CDD:275378 3/22 (14%)
LRR_8 487..545 CDD:290566 19/62 (31%)
leucine-rich repeat 487..510 CDD:275380 8/23 (35%)
leucine-rich repeat 511..534 CDD:275380 6/26 (23%)
LRR_8 533..589 CDD:290566 19/80 (24%)
leucine-rich repeat 535..558 CDD:275380 9/40 (23%)
leucine-rich repeat 559..580 CDD:275380 6/20 (30%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
T05H4.3NP_001343670.1 leucine-rich repeat 69..91 CDD:275380
leucine-rich repeat 92..113 CDD:275380
leucine-rich repeat 114..135 CDD:275380
leucine-rich repeat 136..157 CDD:275380
leucine-rich repeat 158..181 CDD:275380
leucine-rich repeat 182..206 CDD:275380
leucine-rich repeat 629..650 CDD:275380 9/25 (36%)
PLN00113 645..>1005 CDD:331614 93/383 (24%)
leucine-rich repeat 651..672 CDD:275380 7/25 (28%)
leucine-rich repeat 673..692 CDD:275380 4/20 (20%)
leucine-rich repeat 693..714 CDD:275380 4/20 (20%)
leucine-rich repeat 715..761 CDD:275380 14/52 (27%)
leucine-rich repeat 762..815 CDD:275380 16/56 (29%)
leucine-rich repeat 816..851 CDD:275380 5/34 (15%)
leucine-rich repeat 855..875 CDD:275380 6/19 (32%)
leucine-rich repeat 876..903 CDD:275380 6/26 (23%)
leucine-rich repeat 904..952 CDD:275380 9/47 (19%)
leucine-rich repeat 953..973 CDD:275380 6/19 (32%)
leucine-rich repeat 974..994 CDD:275380 7/21 (33%)
leucine-rich repeat 995..1019 CDD:275380 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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