DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and Cysltr2

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_596904.1	Gene:	Cysltr2 / 170926	RGDID:	619797	Length:	309	Species:	Rattus norvegicus

Alignment Length:	294	Identity:	74/294 - (25%)
Similarity:	123/294 - (41%)	Gaps:	57/294 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   762 VVFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAI-VDAATLGEFRMFAI 825
            ::|:...||||..::|.|.:..|.......:.|||.:||   :::..|.. .|....|...:|.
  Rat    31 IIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDF---LFISTLPFRADYNFRGSDWIFG- 91

  Fly   826 PWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFALI 890
            .|    .|::..:...::...|:|.|.|:::.|..|..|...:....|::.|..:..:.|||  |
  Rat    92 DW----ACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVF--I 150

  Fly   891 MALMPLV---GVSDYRKFAVCLPFETTTGPASLTYVISLMFINGCA--------FLTLMGCYLKM 944
            ||...|:   |........:|  ||     .:|....:|:.:|..|        |..|..|||.:
  Rat   151 MASSGLLLKHGQEKKNNTTLC--FE-----LNLQKFKNLVILNYIALGVGFLLPFFILTICYLLI 208

  Fly   945 YWAIRGSQAWNTNDS--RIAKR-------MALLVFTDFLCWSPIAFFSITAIFGLQLIS------ 994
               ||........:|  |.|:|       :|:::|  .||:.|     ..|:..:.|::
  Rat   209 ---IRVLLKVEIPESGPRDAQRKALTTIVIAMIIF--LLCFLP-----YHALRTIHLVTWDADSC 263

  Fly   995 ---LEQAKIFTVFVLPLNSCCNPFLYAIMTKQFK 1025
               |.:|.:.|:.:...|||.|||||....:.||
  Rat   264 MDELHKATVITLTLAAANSCFNPFLYYFAGENFK 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	32/128 (25%)
		7tm_1	770..1017	CDD:278431	68/276 (25%)
Cysltr2	NP_596904.1	TAS2R	24..247	CDD:283059	59/242 (24%)
Cysltr2	NP_596904.1	7tm_1	39..289	CDD:278431	68/276 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910