Protein Alignment rk and Igfals

DIOPT Version :9

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: NP_001351825.1
• Gene: Igfals / 16005
• MGIID: 107973
• Length: 638
• Species: Mus musculus
• Alignment Length: 541
• Identity: 152/541 - (28%)
• Similarity: 225/541 - (41%)
• Gaps: 70/541 - (12%)

  Fly   101 SADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSC 165
            |:.|....|.|.........||.|  .|.....:.|.:.|:         |.|    ||...|..
Mouse   122 SSIPSAAFQNLSSLDFLNLQGSWL--RSLEPQALLGLQNLY---------HLH----LERNLLRS 171

  Fly   166 RGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAKLK 230
            ...|:.....:|.:    |.||||.|.:||...|....:|.:|.|..||::.:....|.||..|.
Mouse   172 LAAGLFRHTPSLAS----LSLGNNLLGRLEEGLFRGLSHLWDLNLGWNSLVVLPDTVFQGLGNLH 232

  Fly   231 RLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNAL 295
            .|.|....|..|.|....||.:|..|.|:.|||.|:..:...||.:|:.|.|:.||...:...|.
Mouse   233 ELVLAGNKLTYLQPALLCGLGELRELDLSRNALRSVKANVFIHLPRLQKLYLDRNLITAVAPRAF 297

  Fly   296 AGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLIS 360
            .|::.|..|:|..|.:..:.::.||.:..|.||.|..|.|..:.....|:|..|:.|:|..|.|.
Mouse   298 LGMKALRWLDLSHNRVAGLLEDTFPGLLGLHVLRLAHNAITSLRPRTFKDLHFLEELQLGHNRIR 362

  Fly   361 SLPE-GLSKLSQLQELSITSNRLRWINDTELPRSMQMLDMRANPLSTISPGAFRGMSKLRKLILS 424
            .|.| ....|.||:.|::..|::.                      .:..|||.|:..:..:.||
Mouse   363 QLGEKTFEGLGQLEVLTLNDNQIH----------------------EVKVGAFFGLFNVAVMNLS 405

  Fly   425 DVRTLRSFPE--LEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRI--PNLSSCR 485
            . ..|||.||  .:....|..|.|:.:.:..:..:.......|:.|.|:.||:..|  .:|:...
Mouse   406 G-NCLRSLPEHVFQGLGRLHSLHLEHSCLGRIRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLS 469

  Fly   486 DLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHK 550
            :|..|||::||:..:..:.|.||.||..||||.|::..|.:|....:.:...|||..|.:....:
Mouse   470 ELLELDLTANQLTHLPRQLFQGLGQLEYLLLSNNQLTMLSEDVLGPLQRAFWLDLSHNRLETPAE 534

  Fly   551 EAFSGFTALEDLNLGNNIFPE-LPESGLRALLHLKTFNNP--------KLREF--PPPDTFPR-I 603
            ..||....|..|||.||.... :|:.||.   .|....||        .||:|  ..|...|| :
Mouse   535 GLFSSLGRLRYLNLRNNSLQTFVPQPGLE---RLWLDANPWDCSCPLKALRDFALQNPGVVPRFV 596

  Fly   604 QTL--------ILSYAYHCCA 616
            ||:        :.:|....||
Mouse   597 QTVCEGDDCQPVYTYNNITCA 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	5/20 (25%)
		LRR_RI	180..>383	CDD:238064	67/203 (33%)
		leucine-rich repeat	183..204	CDD:275380	9/20 (45%)
		LRR_8	203..263	CDD:290566	20/59 (34%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		leucine-rich repeat	229..252	CDD:275380	8/22 (36%)
		LRR_8	252..311	CDD:290566	20/58 (34%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	7/22 (32%)
		LRR_8	299..359	CDD:290566	18/59 (31%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..348	CDD:275380	8/22 (36%)
		LRR_RI	327..567	CDD:238064	68/244 (28%)
		leucine-rich repeat	349..371	CDD:275380	8/22 (36%)
		LRR_8	370..425	CDD:290566	9/54 (17%)
		leucine-rich repeat	372..393	CDD:275380	3/20 (15%)
		leucine-rich repeat	394..415	CDD:275380	3/20 (15%)
		leucine-rich repeat	418..486	CDD:275380	17/71 (24%)
		leucine-rich repeat	441..464	CDD:275378	3/22 (14%)
		LRR_8	487..545	CDD:290566	22/57 (39%)
		leucine-rich repeat	487..510	CDD:275380	9/22 (41%)
		leucine-rich repeat	511..534	CDD:275380	8/22 (36%)
		LRR_8	533..589	CDD:290566	16/56 (29%)
		leucine-rich repeat	535..558	CDD:275380	6/22 (27%)
		leucine-rich repeat	559..580	CDD:275380	9/21 (43%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
Igfals	NP_001351825.1	LRRNT	75..113	CDD:214470
		leucine-rich repeat	92..110	CDD:275380
		PLN00113	96..>558	CDD:331614	135/477 (28%)
		leucine-rich repeat	114..134	CDD:275380	4/11 (36%)
		leucine-rich repeat	135..158	CDD:275380	5/24 (21%)
		leucine-rich repeat	159..182	CDD:275380	7/35 (20%)
		leucine-rich repeat	183..206	CDD:275380	10/26 (38%)
		leucine-rich repeat	207..230	CDD:275380	8/22 (36%)
		leucine-rich repeat	231..254	CDD:275380	8/22 (36%)
		leucine-rich repeat	255..278	CDD:275380	9/22 (41%)
		leucine-rich repeat	279..302	CDD:275380	7/22 (32%)
		leucine-rich repeat	303..326	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	8/22 (36%)
		leucine-rich repeat	351..374	CDD:275380	8/22 (36%)
		leucine-rich repeat	375..396	CDD:275380	6/42 (14%)
		leucine-rich repeat	423..446	CDD:275380	3/22 (14%)
		leucine-rich repeat	447..470	CDD:275380	7/22 (32%)
		leucine-rich repeat	471..494	CDD:275380	9/22 (41%)
		leucine-rich repeat	495..516	CDD:275380	8/20 (40%)
		leucine-rich repeat	519..542	CDD:275380	6/22 (27%)
		leucine-rich repeat	543..561	CDD:275380	7/17 (41%)
		TPKR_C2	570..613	CDD:326558	11/42 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910