DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and AgaP_AGAP011503

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_317796.3	Gene:	AgaP_AGAP011503 / 1278244	VectorBaseID:	AGAP011503	Length:	276	Species:	Anopheles gambiae

Alignment Length:	207	Identity:	57/207 - (27%)
Similarity:	84/207 - (40%)	Gaps:	46/207 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 GNNNLTKLEANSFFMAPNLEELTLSDNS-------IINMDPNAFYGLAKLKRLSLQNCGLKSLPP 244
            ||..:.::|....|...|......|.||       ...::.|      ||.||||.|.||:.|
Mosquito    68 GNGTVAEIERILRFDQSNTVLFLFSSNSDNQNLHTTFTVERN------KLVRLSLDNAGLERL-- 124

  Fly   245 QSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSN 309
                   :||        |:..:.||     :|..|.:..|....:|| .:..|..|..|:...|
Mosquito   125 -------ELT--------LLGRENDC-----RLADLSVPRNRLRDLPT-GVERLTALRKLDYSYN 168

  Fly   310 LLTIINDEDF--PRMPN---LIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKL 369
            ||     |:|  .|:.|   |..|||..|::.:..|....||.||..|:|.:|.:.:|......:
Mosquito   169 LL-----EEFKLDRLANAAGLKQLLLSHNRLERFVATEQVNLAALHKLDLSNNRLRALDASYWTM 228

  Fly   370 SQLQELSITSNR 381
            .||:...:.:||
Mosquito   229 PQLETFHVDNNR 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064	57/207 (28%)
		leucine-rich repeat	183..204	CDD:275380	4/16 (25%)
		LRR_8	203..263	CDD:290566	17/66 (26%)
		leucine-rich repeat	205..228	CDD:275380	4/29 (14%)
		leucine-rich repeat	229..252	CDD:275380	9/22 (41%)
		LRR_8	252..311	CDD:290566	14/58 (24%)
		leucine-rich repeat	253..276	CDD:275380	5/22 (23%)
		leucine-rich repeat	277..300	CDD:275380	6/22 (27%)
		LRR_8	299..359	CDD:290566	22/64 (34%)
		leucine-rich repeat	301..324	CDD:275380	8/24 (33%)
		leucine-rich repeat	325..348	CDD:275380	8/22 (36%)
		LRR_RI	327..567	CDD:238064	17/55 (31%)
		leucine-rich repeat	349..371	CDD:275380	5/21 (24%)
		LRR_8	370..425	CDD:290566	4/12 (33%)
		leucine-rich repeat	372..393	CDD:275380	3/10 (30%)
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
AgaP_AGAP011503	XP_317796.3	LRR	<97..>194	CDD:227223	36/130 (28%)
		leucine-rich repeat	111..136	CDD:275380	14/46 (30%)
		leucine-rich repeat	137..159	CDD:275380	6/22 (27%)
		LRR_8	160..218	CDD:290566	22/62 (35%)
		leucine-rich repeat	160..183	CDD:275380	9/27 (33%)
		leucine-rich repeat	184..207	CDD:275380	8/22 (36%)
		leucine-rich repeat	208..230	CDD:275380	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910