DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and AgaP_AGAP007471

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_308401.2	Gene:	AgaP_AGAP007471 / 1269752	VectorBaseID:	AGAP007471	Length:	406	Species:	Anopheles gambiae

Alignment Length:	402	Identity:	89/402 - (22%)
Similarity:	151/402 - (37%)	Gaps:	106/402 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 LEANSFFMAPNLEEL-------------------------------------TLSDNSIIN--MD 219
            :|.|.:::|.::|:|                                     ||::..|:|  |.
Mosquito    15 IEQNRYYLALSIEKLIVSSSASGPFLQRIATLTEQISYMAYKDPVFQLPADNTLTEIEIVNGVML 79

  Fly   220 PNAFYGLAK-LKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLE 283
            .:...|..: |.||.::||.|..:|| :...:.:|..|.:...||.:|..|.|.:..||..:.|.
Mosquito    80 RSLVAGTNRHLTRLYVENCLLDRIPP-TLSNMIELEGLLIKQCALTALRLDVLVNNPKLTAIDLT 143

  Fly   284 GNLFYRI------PTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGA 342
            .|...::      |...|    .:..|:|..|.|..::...|..||:|....::.|:|::..|.|
Mosquito   144 RNRIRQLFPITTPPKTKL----PVTFLSLAENQLDRLDMSMFAFMPDLERFNVEGNRIVRFEATA 204

  Fly   343 LKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPRSMQMLDMRANPLSTI 407
            .....:|..|.:..|.|:........|::|:.|.|..|.|     ||||..
Mosquito   205 PVTYGSLIRLLVSSNNITQFDTRNLTLTELRSLYINDNAL-----TELPTH-------------- 250

  Fly   408 SPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKT 472
                   ..||..||                    .:..||..::.:..:...:.|.|.|:.:..
Mosquito   251 -------WGKLPNLI--------------------YIGFDRNNLKRIDMSFFEKFPTLISITISE 288

  Fly   473 NSLKRIPNLS--SCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSY--NRIKALPQDAFQGIP 533
            |:::.|...:  :..:|..|..:.|||..:.   |.|....|..|.|:  ||:..:| ..||..|
Mosquito   289 NNVESIRTSTPITMPELEYLMFNGNQIVSVN---FTGCNFPNMYLFSFMNNRLTTIP-PLFQRFP 349

  Fly   534 KLQLLDLEGNEI 545
            ..:|. ::||.|
Mosquito   350 DSRLA-MDGNPI 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064	53/234 (23%)
		leucine-rich repeat	183..204	CDD:275380	3/9 (33%)
		LRR_8	203..263	CDD:290566	18/99 (18%)
		leucine-rich repeat	205..228	CDD:275380	8/61 (13%)
		leucine-rich repeat	229..252	CDD:275380	8/22 (36%)
		LRR_8	252..311	CDD:290566	16/64 (25%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	5/28 (18%)
		LRR_8	299..359	CDD:290566	15/59 (25%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..348	CDD:275380	5/22 (23%)
		LRR_RI	327..567	CDD:238064	49/223 (22%)
		leucine-rich repeat	349..371	CDD:275380	5/21 (24%)
		LRR_8	370..425	CDD:290566	13/54 (24%)
		leucine-rich repeat	372..393	CDD:275380	9/20 (45%)
		leucine-rich repeat	394..415	CDD:275380	0/20 (0%)
		leucine-rich repeat	418..486	CDD:275380	10/69 (14%)
		leucine-rich repeat	441..464	CDD:275378	2/22 (9%)
		LRR_8	487..545	CDD:290566	19/59 (32%)
		leucine-rich repeat	487..510	CDD:275380	7/22 (32%)
		leucine-rich repeat	511..534	CDD:275380	8/24 (33%)
		LRR_8	533..589	CDD:290566	5/13 (38%)
		leucine-rich repeat	535..558	CDD:275380	4/11 (36%)
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
AgaP_AGAP007471	XP_308401.2	LRR_8	88..147	CDD:290566	19/59 (32%)
		leucine-rich repeat	90..112	CDD:275380	8/22 (36%)
		leucine-rich repeat	113..136	CDD:275380	7/22 (32%)
		LRR_8	135..197	CDD:290566	15/65 (23%)
		leucine-rich repeat	137..160	CDD:275380	4/22 (18%)
		leucine-rich repeat	161..186	CDD:275380	7/28 (25%)
		leucine-rich repeat	187..210	CDD:275380	5/22 (23%)
		leucine-rich repeat	211..233	CDD:275380	5/21 (24%)
		LRR_8	232..291	CDD:290566	19/104 (18%)
		leucine-rich repeat	234..256	CDD:275380	11/47 (23%)
		leucine-rich repeat	257..280	CDD:275380	4/42 (10%)
		leucine-rich repeat	281..304	CDD:275380	4/22 (18%)
		leucine-rich repeat	305..327	CDD:275380	7/24 (29%)
		leucine-rich repeat	328..350	CDD:275380	7/22 (32%)
		leucine-rich repeat	351..370	CDD:275380	4/11 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910