DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and LOC116412268

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_031761986.1	Gene:	LOC116412268 / 116412268	-ID:	-	Length:	332	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	72/290 - (24%)
Similarity:	115/290 - (39%)	Gaps:	43/290 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   760 VWV--VFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRM 822
            ||:  .|:|..||||.|::| ...:.|..|......|||..||...:.||.  .:....|..:..
Frog    40 VWLSTTFILGTLGNGLVIWV-FGFKMKKTVNTIWFLNLAIVDFCFCLSLGF--YIPVVILNHWPF 101

  Fly   823 FAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVF 887
            ..||      |:|:..:..|:..:||:.||||:.:|...:.:.|......:|:.|.....:.|:.
Frog   102 GQIP------CKLTTCILDLNMAVSVFFLAVISFDRCLCVLYPIRSRSHRTLRLAVISSVMIWLL 160

  Fly   888 ALIMALMPLV--GVSDYRKFAVCLPFETTTGPAS---------------LTYVISLMFINGCAFL 935
            .|.::...||  .|......:||   .:|.|..:               ||..:|:..|   .|.
Frog   161 GLAVSSPSLVFTNVVHGGNISVC---GSTYGNGADGSNVHSPTRQKVMILTRFVSVFLI---PFT 219

  Fly   936 TLMGCYLKMYWAIRGSQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQL-----ISL 995
            .::.||..:.:.:|.|.. ....:|..|.:..:|...|.||.|.....:..|.|..:     ..:
Frog   220 IILVCYGLISFRVRRSSR-PPGSARTFKIIITVVLCFFFCWFPFHLMFLKEITGFNIKWPYGYII 283

  Fly   996 EQAKIFTVFVLPLNSCCNPFLYAIMTKQFK 1025
            ....|...|   .|||.||.:|..:.:.||
Frog   284 SHMAICLAF---FNSCLNPMVYVFVGQNFK 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	35/127 (28%)
		7tm_1	770..1017	CDD:278431	64/268 (24%)
LOC116412268	XP_031761986.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910