DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and LOC116409470

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_031753985.1	Gene:	LOC116409470 / 116409470	-ID:	-	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	458	Identity:	99/458 - (21%)
Similarity:	184/458 - (40%)	Gaps:	98/458 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 NCGLKSLP-PQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLR-----LEGNLFYRIPTN- 293
            :|.|..|. ..|.....|.:||:..|...|..:...|.:::..:.|.     |...:|..:..:
Frog    18 SCSLVDLTNVMSIVSCIQASSLEFQGGRFVDTEEYSLHNVEMEQVLAMIHLPLSKVVFANVVISE 82

  Fly   294 --ALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDD 356
              .|:.|..::.:.:  |:|..:|.....|.        |:.|:    :|:...:.:|:|:.
Frog    83 EFLLSFLNWVQRIQI--NVLAFVNTTFEGRS--------KKQQM----SGSPPQILSLQVIN--- 130

  Fly   357 NLISSLP--------EGLSK-LSQLQELSITSNRLRWI--NDTELPRSMQMLDMRANPL------ 404
              :.|.|        .|||. :..|::|::|.:.|..|  |.:...:.:..||:..|.|
Frog   131 --VPSYPLLDRVSTFSGLSSWIYNLEDLTLTKSHLTGIPCNTSRQFKILSSLDLSENLLQDENIS 193

  Fly   405 STISPGAFRGMSKLR----KLILSDV--RTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTP 463
            |:...|||..:..|:    :|:..|.  :||....:|:  |    |.|.:..:.....:||...|
Frog   194 SSFCQGAFPNIKTLKLNHNRLVSFDTICQTLNKQNQLK--H----LDLSQNNLSSTSTSLCEWQP 252

  Fly   464 RLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDA 528
            .|..|.|....|:.:||:.. |:..:||||.|:::.:.    ..|..|.:|.||:|.:..:  ..
Frog   253 SLALLNLSDTGLEELPNILP-RNCEILDLSYNKLDALN----LSLPSLKELYLSHNLLTTI--ST 310

  Fly   529 FQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLH---LKTFNNPK 590
            .:..|.||.|.:.||.|..:.:.....|..:..:...|     :|.:...:|:|   ..|.::..
Frog   311 VENFPCLQTLAINGNPIKTLQRGQLQYFRHISSIRADN-----IPYTCSCSLVHEMNEMTMSSLT 370

  Fly   591 LREFP------PPDTF--PRIQTLILSYAYHC---------CAFLPLVAMSS--------QKKTS 630
            .:.:|      .||..  .|:..:.||: :.|         |....||.:::        |.|.:
Frog   371 FQHWPDGYICASPDLLKGQRVSEVKLSF-FECHKPLLTVLICIVSLLVLVAAVICIHKFHQSKKT 434

  Fly   631 QVQ 633
            ::|
Frog   435 RLQ 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064	32/164 (20%)
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566	8/27 (30%)
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380	4/16 (25%)
		LRR_8	252..311	CDD:290566	12/66 (18%)
		leucine-rich repeat	253..276	CDD:275380	5/22 (23%)
		leucine-rich repeat	277..300	CDD:275380	5/30 (17%)
		LRR_8	299..359	CDD:290566	9/59 (15%)
		leucine-rich repeat	301..324	CDD:275380	4/22 (18%)
		leucine-rich repeat	325..348	CDD:275380	3/22 (14%)
		LRR_RI	327..567	CDD:238064	62/262 (24%)
		leucine-rich repeat	349..371	CDD:275380	7/30 (23%)
		LRR_8	370..425	CDD:290566	16/66 (24%)
		leucine-rich repeat	372..393	CDD:275380	6/22 (27%)
		leucine-rich repeat	394..415	CDD:275380	8/26 (31%)
		leucine-rich repeat	418..486	CDD:275380	18/73 (25%)
		leucine-rich repeat	441..464	CDD:275378	4/22 (18%)
		LRR_8	487..545	CDD:290566	17/57 (30%)
		leucine-rich repeat	487..510	CDD:275380	6/22 (27%)
		leucine-rich repeat	511..534	CDD:275380	5/22 (23%)
		LRR_8	533..589	CDD:290566	13/58 (22%)
		leucine-rich repeat	535..558	CDD:275380	7/22 (32%)
		leucine-rich repeat	559..580	CDD:275380	2/20 (10%)
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
LOC116409470	XP_031753985.1	PRK15370	<120..>372	CDD:185268	64/274 (23%)
		leucine-rich repeat	153..176	CDD:275380	6/22 (27%)
		leucine-rich repeat	177..203	CDD:275380	8/25 (32%)
		leucine-rich repeat	204..229	CDD:275380	5/24 (21%)
		leucine-rich repeat	230..253	CDD:275380	6/28 (21%)
		leucine-rich repeat	254..275	CDD:275380	7/21 (33%)
		leucine-rich repeat	295..316	CDD:275380	5/22 (23%)
		leucine-rich repeat	317..336	CDD:275380	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910