DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rk and podn

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:XP_031756818.1 Gene:podn / 101730272 XenbaseID:XB-GENE-963382 Length:598 Species:Xenopus tropicalis


Alignment Length:494 Identity:138/494 - (27%)
Similarity:217/494 - (43%) Gaps:76/494 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 CHCTGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSII 216
            |.|  |.|...::|.|:.:...|.|||:.::.|.|.||.:.::..........||.|.|.:|.:.
 Frog    63 CKC--SQEGAVVNCAGVDLREFPSNLPDIIIHLSLQNNQIEEIPPEDLTRLYKLETLNLQNNRLT 125

  Fly   217 N--MDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRT 279
            :  :..:.|..|.||..|.|.|..| ||.|:...  :.|.|.....|.:..:.....||...||:
 Frog   126 SRGIPDDLFEHLEKLNYLYLANNKL-SLAPRFLP--SSLISADFAANNITKIYEMTFGHKPNLRS 187

  Fly   280 LRLEGNLF--YRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGA 342
            :.|..|..  ..||.|.......:|.|.|.||.|..: .::.|  |.|..|.|:.|::..|.:||
 Frog   188 VYLHDNKLTDAGIPDNMFNRSNRVETLILSSNFLKYV-PKNLP--PALCKLHLQNNKLESIPSGA 249

  Fly   343 LKNLTALKVLELDDNLISSLPEGL-----SKLSQLQELSITSNRLRWINDTELPRSMQMLDMRAN 402
            ..:||.|:.|.|.:|.:|:  ||:     :||::|:.|.::||.|..| .:.|||::.:|.:..|
 Frog   250 FSHLTDLRELYLLNNRLSN--EGMDNETFTKLNKLEYLDLSSNNLTKI-PSGLPRNIVILHLEKN 311

  Fly   403 PLSTIS--------------------------PGAFRGMSKLRKLILSD-------------VRT 428
            .:..||                          ||||.|:.||..:.:.:             |:|
 Frog   312 SIRFISDNVLTQIRNLEYLLLHNNKLRAHGIHPGAFVGLKKLHTVHVYNNLLEKVPPGLPRRVKT 376

  Fly   429 LR---------SFPELEACHALEILKLDRAGIQ--EVPANLCRQTPRLKSLELKTNSLKRIPNLS 482
            |.         |..:....:.||.|.|....|.  .|.....|:...||:|||..|:||.:| ..
 Frog   377 LMLLHNQISSISKNDFATTYLLEDLNLSYNKIMSGNVHKEAFRKLRLLKTLELSGNNLKSVP-YG 440

  Fly   483 SCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIK--ALPQDAFQGIPKLQLLDLEGNEI 545
            ..::|.:|.|..|.|..|......|:.:|.:..||.|::|  :....|:..:..||:|||.||::
 Frog   441 LPKNLEILRLKDNDISSIPQDSLTGMIKLKEFYLSNNKLKLSSFYSGAWAELSSLQILDLSGNQL 505

  Fly   546 SYIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLHLK 584
            |||..:...   .||.|.|.:|....:.:|...:..::|
 Frog   506 SYIPSDLPE---TLEYLYLQSNKIITVDDSAFESTPNIK 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 6/20 (30%)
LRR_RI 180..>383 CDD:238064 62/211 (29%)
leucine-rich repeat 183..204 CDD:275380 4/20 (20%)
LRR_8 203..263 CDD:290566 19/61 (31%)
leucine-rich repeat 205..228 CDD:275380 7/24 (29%)
leucine-rich repeat 229..252 CDD:275380 8/22 (36%)
LRR_8 252..311 CDD:290566 17/60 (28%)
leucine-rich repeat 253..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..300 CDD:275380 7/24 (29%)
LRR_8 299..359 CDD:290566 21/59 (36%)
leucine-rich repeat 301..324 CDD:275380 7/22 (32%)
leucine-rich repeat 325..348 CDD:275380 8/22 (36%)
LRR_RI 327..567 CDD:238064 84/296 (28%)
leucine-rich repeat 349..371 CDD:275380 9/26 (35%)
LRR_8 370..425 CDD:290566 20/80 (25%)
leucine-rich repeat 372..393 CDD:275380 8/20 (40%)
leucine-rich repeat 394..415 CDD:275380 8/46 (17%)
leucine-rich repeat 418..486 CDD:275380 21/91 (23%)
leucine-rich repeat 441..464 CDD:275378 7/24 (29%)
LRR_8 487..545 CDD:290566 20/59 (34%)
leucine-rich repeat 487..510 CDD:275380 7/22 (32%)
leucine-rich repeat 511..534 CDD:275380 6/24 (25%)
LRR_8 533..589 CDD:290566 17/52 (33%)
leucine-rich repeat 535..558 CDD:275380 10/22 (45%)
leucine-rich repeat 559..580 CDD:275380 6/20 (30%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
podnXP_031756818.1 LRRNT 59..87 CDD:396168 8/25 (32%)
leucine-rich repeat 90..113 CDD:275380 4/22 (18%)
PLN00113 105..>512 CDD:215061 117/416 (28%)
leucine-rich repeat 114..139 CDD:275380 7/24 (29%)
leucine-rich repeat 140..184 CDD:275380 13/46 (28%)
leucine-rich repeat 185..210 CDD:275380 7/24 (29%)
leucine-rich repeat 211..231 CDD:275380 7/22 (32%)
leucine-rich repeat 232..255 CDD:275380 8/22 (36%)
leucine-rich repeat 256..281 CDD:275380 9/26 (35%)
leucine-rich repeat 282..302 CDD:275380 8/20 (40%)
leucine-rich repeat 303..326 CDD:275380 4/22 (18%)
leucine-rich repeat 327..352 CDD:275380 5/24 (21%)
leucine-rich repeat 353..373 CDD:275380 1/19 (5%)
leucine-rich repeat 374..397 CDD:275380 4/22 (18%)
leucine-rich repeat 398..423 CDD:275380 7/24 (29%)
leucine-rich repeat 424..445 CDD:275380 9/21 (43%)
leucine-rich repeat 446..468 CDD:275380 6/21 (29%)
leucine-rich repeat 469..494 CDD:275380 6/24 (25%)
leucine-rich repeat 495..515 CDD:275380 10/22 (45%)
LRR_8 515..575 CDD:404697 7/27 (26%)
leucine-rich repeat 516..539 CDD:275380 6/22 (27%)
leucine-rich repeat 540..565 CDD:275380 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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