DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and nrros

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_001231915.1 Gene:nrros / 100498580 XenbaseID:XB-GENE-986206 Length:679 Species:Xenopus tropicalis


Alignment Length:625 Identity:148/625 - (23%)
Similarity:248/625 - (39%) Gaps:144/625 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 EYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSCRGIGILAVPVNLPNEVV 182
            :|:|::            ||.:..|.|:.:.:.            ..|..:.:|:||.|||.::.
 Frog    20 KYNGAE------------GKLSTESGCKLFYRV------------ADCSHLQLLSVPQNLPTDIQ 60

  Fly   183 VLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSF 247
            .|.|..|.:..|..|||....:|..|:|..|.:..::|.||.|:..||.|||||        .:.
 Frog    61 ELLLDFNQIRFLHKNSFLRYHDLTNLSLRSNRMEFVEPGAFNGIRSLKVLSLQN--------NTI 117

  Fly   248 QGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNAL-AGLRTLEALNLGSNLL 311
            ....:|||..|.             ....|:.|.|..|:......:.| ..|.:||.|.|.:|::
 Frog   118 SMEYELTSAALR-------------LTPSLKELDLSRNMLTMDMVSVLHQNLTSLERLFLDNNII 169

  Fly   312 TIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELS 376
            ..::...|..:.:|..|.|:.|.|.:|..|..:.|..||.|:|..||:..:  |..:|:|:|.|:
 Frog   170 MRLDQTVFEGLVHLKELSLQWNYIYEIEDGTFEGLVKLKKLDLAYNLLPCI--GDFRLTQIQMLN 232

  Fly   377 ITSNRLRWI--NDTELPRSMQMLDMRANPL--STISPGAFRGMSKLRKLILSDVRTLRSFPELEA 437
            ::.|.|.|.  .:|::...:::||:..|.|  ..:.|...|    |..|:||:.| :|.:.::..
 Frog   233 LSFNNLEWFQSQETDVEFHLEILDISNNQLLFFPLLPRQHR----LHTLLLSNNR-MRFYGDIFG 292

  Fly   438 CHALEILKLDRAGIQEVPANLCRQT-------------PRLKSLELKTNSLKRIPN--LSSCRDL 487
            .:.      .||....|..|:...|             ..|..|::..|.....|:  .|:...|
 Frog   293 TNT------SRADFLIVENNITSVTTVDLWSDDIHSNLSTLHYLDMSHNQFAFFPHGFFSNMSSL 351

  Fly   488 RLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQ-GIPKLQLLDLEGNEISYIHKE 551
            ..|.|:.|.::.....|.|....|::|.||.|.:..|..|... ||..|...:|..|.:..:.|.
 Frog   352 AYLKLNWNCLQVFSVSPSNITSLLDELDLSNNELLELQADNISPGILSLSYFNLSSNNLYNLPKN 416

  Fly   552 AFSGFTALEDLNLGNNIFPELPESGLR------------------------------------AL 580
            .|:..|.:..:::.||......:|.||                                    .|
 Frog   417 IFTSMTRIHTIDMSNNPLHLCSQSELRMGEGKCVDVRNVPSLRRLYLSGCGMELGLQRVFYGNTL 481

  Fly   581 LHLK-TFNNPKLREFPPPDTFPRIQTLILSYAYHCCAF-----------LPLVAMSSQKKTSQVQ 633
            .||. ::||.|...| ..||...:|:|.|.   .|.||           |.::.:|....|:   
 Frog   482 THLDLSYNNIKGITF-LADTARTLQSLFLR---SCLAFNITVDFSVFMSLTVLDISGNALTT--- 539

  Fly   634 EAVLFPSD----AEFDMTLWNNSMMNIWPQMHNLSKQLGA 669
                ||:.    |...:.|.||:::::  .::|..:.:|:
 Frog   540 ----FPASLTGLALHYLDLHNNNLISL--PLYNTQRLIGS 573

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 6/20 (30%)
LRR_RI 180..>383 CDD:238064 58/203 (29%)
leucine-rich repeat 183..204 CDD:275380 7/20 (35%)
LRR_8 203..263 CDD:290566 19/59 (32%)
leucine-rich repeat 205..228 CDD:275380 8/22 (36%)
leucine-rich repeat 229..252 CDD:275380 7/22 (32%)
LRR_8 252..311 CDD:290566 15/59 (25%)
leucine-rich repeat 253..276 CDD:275380 4/22 (18%)
leucine-rich repeat 277..300 CDD:275380 6/23 (26%)
LRR_8 299..359 CDD:290566 19/59 (32%)
leucine-rich repeat 301..324 CDD:275380 6/22 (27%)
leucine-rich repeat 325..348 CDD:275380 8/22 (36%)
LRR_RI 327..567 CDD:238064 65/259 (25%)
leucine-rich repeat 349..371 CDD:275380 8/21 (38%)
LRR_8 370..425 CDD:290566 16/58 (28%)
leucine-rich repeat 372..393 CDD:275380 6/22 (27%)
leucine-rich repeat 394..415 CDD:275380 6/22 (27%)
leucine-rich repeat 418..486 CDD:275380 16/82 (20%)
leucine-rich repeat 441..464 CDD:275378 5/35 (14%)
LRR_8 487..545 CDD:290566 18/58 (31%)
leucine-rich repeat 487..510 CDD:275380 6/22 (27%)
leucine-rich repeat 511..534 CDD:275380 9/23 (39%)
LRR_8 533..589 CDD:290566 15/92 (16%)
leucine-rich repeat 535..558 CDD:275380 5/22 (23%)
leucine-rich repeat 559..580 CDD:275380 5/56 (9%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
nrrosNP_001231915.1 leucine-rich repeat 39..58 CDD:275380 7/30 (23%)
leucine-rich repeat 59..82 CDD:275380 7/22 (32%)
LRR_8 60..115 CDD:404697 22/62 (35%)
leucine-rich repeat 83..106 CDD:275380 8/22 (36%)
leucine-rich repeat 107..133 CDD:275380 11/46 (24%)
internalin_A 108..>495 CDD:380193 99/420 (24%)
leucine-rich repeat 134..158 CDD:275380 6/23 (26%)
leucine-rich repeat 159..182 CDD:275380 6/22 (27%)
leucine-rich repeat 183..206 CDD:275380 8/22 (36%)
leucine-rich repeat 207..227 CDD:275380 8/21 (38%)
leucine-rich repeat 228..251 CDD:275380 6/22 (27%)
leucine-rich repeat 274..326 CDD:275380 11/58 (19%)
leucine-rich repeat 327..350 CDD:275380 5/22 (23%)
leucine-rich repeat 351..374 CDD:275380 6/22 (27%)
leucine-rich repeat 375..399 CDD:275380 9/23 (39%)
leucine-rich repeat 400..421 CDD:275380 5/20 (25%)
leucine-rich repeat 424..457 CDD:275380 5/32 (16%)
leucine-rich repeat 458..480 CDD:275380 0/21 (0%)
leucine-rich repeat 481..503 CDD:275380 9/22 (41%)
leucine-rich repeat 504..526 CDD:275380 6/24 (25%)
leucine-rich repeat 527..548 CDD:275380 5/27 (19%)
leucine-rich repeat 574..586 CDD:275378 148/625 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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