Protein Alignment rk and adora2b

DIOPT Version :9

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: XP_012812980.1
• Gene: adora2b / 100496230
• XenbaseID: XB-GENE-1013395
• Length: 337
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 67/305 - (21%)
• Similarity: 133/305 - (43%)
• Gaps: 65/305 - (21%)

  Fly   762 VVFLLSLLGNGTVVFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLG-----EFR 821
            ::.:||:.||..|.:.:..:.:..:...:.:.:||.||    |.:|:|||..|.|:.     :|.
 Frog    13 IIAVLSIAGNVLVCWAVAINSTLKNATNYFLVSLAVAD----IAVGLLAIPFAITISIGLETDFH 73

  Fly   822 MFAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWV 886
            .          |.......::.::.|:::|..:.::|..||...:.....:|.|:|..|::|.|:
 Frog    74 S----------CLFFACFVLVLTQSSIFSLLAVAIDRYLAIKIPLRYKSLVSGKRARAIIAVFWI 128

  Fly   887 FALIMALMPLVGVSDYRK------------FAVCLPFETTTGPASLTYVISLMFINGCAF----- 934
            .:.::.|:||:|.:...|            ...|| ||..   .:::|::   :.|...|
 Frog   129 LSFVIGLIPLMGWNRLDKNCSHEPGMSHNCTVQCL-FEKV---VTMSYMV---YFNFFGFVLLPL 186

  Fly   935 LTLMGCYLKMYWAIR-----------GSQAWNT---NDSRIAKRMALLVFTDFLCWSPIAFFSIT 985
            |.::|.|:|::...|           ||.:..:   .:...||.:|::|.....||.||...:..
 Frog   187 LIMLGIYIKIFMVARKQLRQIELKCVGSDSSRSILQKEVNAAKSLAIIVGLFAFCWLPIHILNCI 251

  Fly   986 AIFGLQLISLEQAK----IFTVFVLP-LNSCCNPFLYAIMTKQFK 1025
            .:|   :...::.|    ::|..:|. .||..||.:||...:.|:
 Frog   252 TLF---MPDFDKTKPEWVMYTAIILSHANSVVNPIIYAYKIRDFR 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	29/132 (22%)
		7tm_1	770..1017	CDD:278431	62/287 (22%)
adora2b	XP_012812980.1	7tm_GPCRs	7..296	CDD:391938	67/305 (22%)
		TM helix 1	7..31	CDD:341315	5/17 (29%)
		TM helix 2	40..62	CDD:341315	9/25 (36%)
		TM helix 3	76..98	CDD:341315	2/21 (10%)
		TM helix 4	121..137	CDD:341315	4/15 (27%)
		TM helix 5	171..194	CDD:341315	5/25 (20%)
		TM helix 6	225..250	CDD:341315	8/24 (33%)
		TM helix 7	264..289	CDD:341315	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910