Protein Alignment rk and LOC100494508

DIOPT Version :9

• Sequence 1: NP_476702.1
• Gene: rk / 34819
• FlyBaseID: FBgn0003255
• Length: 1360
• Species: Drosophila melanogaster
• Sequence 2: XP_002938964.2
• Gene: LOC100494508 / 100494508
• -ID: -
• Length: 713
• Species: Xenopus tropicalis
• Alignment Length: 776
• Identity: 194/776 - (25%)
• Similarity: 294/776 - (37%)
• Gaps: 242/776 - (31%)

  Fly   303 ALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLS 367
            ||||..|.:..::|..|.|..:|..|||:.|::..||..|...|..||:|.|..|.|.||..|:.
 Frog   129 ALNLKDNKIKTLHDGIFSRYQDLEKLLLQNNELHDISRLAFSGLFKLKMLFLSQNRIRSLKAGVF 193

  Fly   368 KLSQLQELSITSNRLRWINDTELPRSMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSF 432
            |                    :| ||::.|.:..|.:|.|.||.|.|
 Frog   194 K--------------------DL-RSLEWLILDNNQVSKIVPGTFSG------------------ 219

  Fly   433 PELEACHALEILKLDRAGIQEVPAN-LCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQ 496
              ||:.:.|::|   ...|:|:|.| :|.:.|.|..|:|:.|.::.|.:......:.:|.|..|.
 Frog   220 --LESLYFLDML---NNSIREIPRNSICEEMPHLNWLDLEGNQMQTIHSSVFQECITVLSLRRNN 279

  Fly   497 IEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALED 561
            |.||:....:.:.:|.||.||.|:|..|....|..:..||.|::..|.:.:|....|...:.|:.
 Frog   280 IRKIRKGALSQMNKLVDLDLSMNQIVELSPSLFTNLRDLQQLNISFNPLQHIQPNQFDLLSNLQS 344

  Fly   562 LNLGNNIFPELPESGLRALLHLKTFNNPKLREFPPPDTFPRIQTLILSYAY----HCCAFLPLVA 622
            ||:.:   .|:|.      :|.:.|::                .:.||:.|    ..|::.|.|
 Frog   345 LNMED---IEIPN------IHNRMFSS----------------LVNLSHIYFKKFQYCSYAPHV- 383

  Fly   623 MSSQKKTSQVQEAVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGASMHDPWETAINFNEEQLQ 687
             .|.|..|.             .::.:.|.:.||
 Frog   384 -RSCKPNSD-------------GISSFENLLANI------------------------------- 403

  Fly   688 TQTGGQIATSYMEEYFEEHDVSGPATGYGFGTGLFSGMSTEDFQPGSVQCLPMPGPFLPCADLFD 752
                                                                             
 Frog   404 ----------------------------------------------------------------- 403

  Fly   753 WWTLRCGVWVVFLLSLLGNGTVVFVLLCSRSKMDVPRFLV---C-------NLAAADFFMGIYLG 807
              .||..|||:..::..||   :|| :|.||      |:|   |       :|..||..||.||.
 Frog   404 --LLRVFVWVMACVTCFGN---LFV-ICMRS------FIVTENCQHTMSIKSLCCADCLMGFYLF 456

  Fly   808 ILAIVDAATLGEFRMFAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAI-HLNKR 871
            .|...|....||:...|..|..|..|:|.|.||:||||:||..|..:|||:...|.... |.  |
 Frog   457 CLGAFDIKFQGEYNKHAQAWMESWECKLVGSLAMLSSEVSVMMLTYMTLEKYLCIVFPFSHF--R 519

  Fly   872 LSLKQAGYIMSVGWVFALIMALMPLVGVSDYRKF----AVCLPF--ETTTGPASLTYVISLMF-I 929
            ....|....::..|.....:.::|......:..|    .||.|.  ::|....:..|.:|:.. :
 Frog   520 AGRGQTLCTLTAIWGLGFFITVIPFFSYDTFGNFYGRNGVCFPLQSDSTEKYGARGYSVSIFLGL 584

  Fly   930 NGCAFLTLMGCYLKMYWAIRGSQAWNTNDS------RIAKRMALLVFTDFLCWSPIAFFSITAIF 988
            |..||:|::..|..|:::|..:.|.....|      .||||...:||||.|||.|        ||
 Frog   585 NLLAFVTIVFSYSSMFYSIHKTGAKTAERSVLSREVTIAKRFFFIVFTDALCWIP--------IF 641

  Fly   989 GLQLISLEQAKI-------FTVFVLPLNSCCNPFLYAIMTKQFK---KDCVTLCKHFEESR 1039
            .|:.:||.:|:|       ..:|:||:||..||.||.:.|..|:   |.|:. .|..|.|:
 Frog   642 LLKAVSLTEAEIPGTITSWIVIFILPINSALNPILYTLTTSSFQEKLKQCLQ-SKRQESSK 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064	27/79 (34%)
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566	5/7 (71%)
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566	22/55 (40%)
		leucine-rich repeat	301..324	CDD:275380	8/20 (40%)
		leucine-rich repeat	325..348	CDD:275380	9/22 (41%)
		LRR_RI	327..567	CDD:238064	68/240 (28%)
		leucine-rich repeat	349..371	CDD:275380	10/21 (48%)
		LRR_8	370..425	CDD:290566	11/54 (20%)
		leucine-rich repeat	372..393	CDD:275380	1/20 (5%)
		leucine-rich repeat	394..415	CDD:275380	7/20 (35%)
		leucine-rich repeat	418..486	CDD:275380	15/68 (22%)
		leucine-rich repeat	441..464	CDD:275378	7/23 (30%)
		LRR_8	487..545	CDD:290566	19/57 (33%)
		leucine-rich repeat	487..510	CDD:275380	6/22 (27%)
		leucine-rich repeat	511..534	CDD:275380	9/22 (41%)
		LRR_8	533..589	CDD:290566	13/55 (24%)
		leucine-rich repeat	535..558	CDD:275380	6/22 (27%)
		leucine-rich repeat	559..580	CDD:275380	5/20 (25%)
		7tm_4	764..>892	CDD:304433	44/138 (32%)
		7tm_1	770..1017	CDD:278431	87/277 (31%)
LOC100494508	XP_002938964.2	LDLa	29..64	CDD:238060
		leucine-rich repeat	108..126	CDD:275378
		internalin_A	125..>369	CDD:380193	83/308 (27%)
		leucine-rich repeat	127..150	CDD:275380	8/20 (40%)
		leucine-rich repeat	151..174	CDD:275380	9/22 (41%)
		leucine-rich repeat	175..198	CDD:275380	11/43 (26%)
		leucine-rich repeat	199..222	CDD:275380	9/42 (21%)
		leucine-rich repeat	223..247	CDD:275380	7/26 (27%)
		leucine-rich repeat	248..269	CDD:275380	5/20 (25%)
		leucine-rich repeat	271..293	CDD:275380	6/21 (29%)
		leucine-rich repeat	294..317	CDD:275380	9/22 (41%)
		leucine-rich repeat	318..341	CDD:275380	6/22 (27%)
		leucine-rich repeat	342..363	CDD:275380	7/45 (16%)
		7tm_GPCRs	403..688	CDD:391938	97/402 (24%)
		TM helix 1	405..429	CDD:341315	12/33 (36%)
		TM helix 2	438..459	CDD:341315	7/20 (35%)
		TM helix 3	483..505	CDD:341315	11/21 (52%)
		TM helix 4	527..543	CDD:341315	1/15 (7%)
		TM helix 5	575..598	CDD:341315	7/22 (32%)
		TM helix 6	620..645	CDD:341315	15/32 (47%)
		TM helix 7	656..681	CDD:341315	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910