DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and lrrc4

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:XP_002939414.1 Gene:lrrc4 / 100493671 XenbaseID:XB-GENE-968937 Length:641 Species:Xenopus tropicalis


Alignment Length:503 Identity:119/503 - (23%)
Similarity:188/503 - (37%) Gaps:147/503 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   290 IPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLEL 354
            ||:|.       .:|||..|.:.:|..:.|..:.:|.||.|.||.|.:|..||...|.:|..|||
 Frog    67 IPSNT-------RSLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLEL 124

  Fly   355 DDNLISSLPEG-LSKLSQLQELSITSNRLRWINDTELPRSMQMLDMRANPLSTISPGAFRGMSKL 418
            .||.::.:|.| ...||:|:||        |              :|.||:.:|...||..:..|
 Frog   125 FDNWLTVIPSGAFEYLSKLREL--------W--------------LRNNPIESIPSYAFNRVPSL 167

  Fly   419 RKLILSDVRTLRSFPE--LEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNL 481
            .:|.|.:::.|....|  .|..:.|:.|.|....|::                        :|||
 Frog   168 MRLDLGELKKLEYISEGAFEGLYNLKYLNLGMCNIRD------------------------MPNL 208

  Fly   482 SSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEIS 546
            :....|..|::|.|...:|:...|:||:.|.                     ||.:::   ::|:
 Frog   209 TPLVGLEELEISGNNFPEIKPGSFHGLRSLK---------------------KLWIMN---SQIN 249

  Fly   547 YIHKEAFSGFTALEDLNLGNNIFPELPE---SGLRALLHLKTFNNP------------KLREFPP 596
            .|.:.||...|:|.:|||.:|....||.   :.|:.|:.|...:||            .|||:.|
 Frog   250 TIERNAFDDLTSLVELNLAHNNVTSLPHDLFAPLKYLVELHLHHNPWDCDCDVLWLSWWLREYIP 314

  Fly   597 PDTFPRIQTLILSYAYHCCAFLPLVAMSSQKKTSQVQEAVL-----FPSDAEFDMTLWNNSMMNI 656
            .::             .||...........|...:|..::.     |..||..|:.:....|..:
 Frog   315 TNS-------------TCCGRCHSPPHMRGKYVVEVDHSMFQCSAPFIMDAPRDLNISEGRMAEL 366

  Fly   657 -----------WPQMHNLSKQLGASMHDPWETAIN---FNEEQ-LQTQT-----------GGQIA 695
                       | .:.|.:....||.| |..|.:|   .|..| |.|.|           |...|
 Frog   367 KCRTSAMSSVRW-LLPNGTVLTHASNH-PRITILNDGTLNFSQVLLTDTGVYTCMVTNVAGNSNA 429

  Fly   696 TSYMEEYFEEHDVSGPATGYGFGTGLFSGMSTEDFQPGSVQCLPMPGP 743
            ::|:.....|.:.|    .|.|.|.:  .:.|.:..|..:..:..|.|
 Frog   430 SAYLNVSTAELNTS----NYSFFTTV--TVETTEVAPEDISMIFKPVP 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064 33/93 (35%)
leucine-rich repeat 183..204 CDD:275380
LRR_8 203..263 CDD:290566
leucine-rich repeat 205..228 CDD:275380
leucine-rich repeat 229..252 CDD:275380
LRR_8 252..311 CDD:290566 7/20 (35%)
leucine-rich repeat 253..276 CDD:275380
leucine-rich repeat 277..300 CDD:275380 3/9 (33%)
LRR_8 299..359 CDD:290566 23/59 (39%)
leucine-rich repeat 301..324 CDD:275380 6/22 (27%)
leucine-rich repeat 325..348 CDD:275380 11/22 (50%)
LRR_RI 327..567 CDD:238064 63/242 (26%)
leucine-rich repeat 349..371 CDD:275380 9/22 (41%)
LRR_8 370..425 CDD:290566 14/54 (26%)
leucine-rich repeat 372..393 CDD:275380 4/20 (20%)
leucine-rich repeat 394..415 CDD:275380 6/20 (30%)
leucine-rich repeat 418..486 CDD:275380 13/69 (19%)
leucine-rich repeat 441..464 CDD:275378 4/22 (18%)
LRR_8 487..545 CDD:290566 11/57 (19%)
leucine-rich repeat 487..510 CDD:275380 8/22 (36%)
leucine-rich repeat 511..534 CDD:275380 1/22 (5%)
LRR_8 533..589 CDD:290566 17/58 (29%)
leucine-rich repeat 535..558 CDD:275380 5/22 (23%)
leucine-rich repeat 559..580 CDD:275380 8/23 (35%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
lrrc4XP_002939414.1 LRRNT 40..71 CDD:214470 2/3 (67%)
LRR <68..285 CDD:227223 76/293 (26%)
leucine-rich repeat 71..94 CDD:275380 6/29 (21%)
leucine-rich repeat 95..118 CDD:275380 11/22 (50%)
leucine-rich repeat 119..142 CDD:275380 9/22 (41%)
leucine-rich repeat 143..166 CDD:275380 10/44 (23%)
leucine-rich repeat 167..191 CDD:275380 6/23 (26%)
leucine-rich repeat 192..213 CDD:275380 7/44 (16%)
leucine-rich repeat 214..237 CDD:275380 8/22 (36%)
leucine-rich repeat 238..261 CDD:275380 7/46 (15%)
leucine-rich repeat 262..283 CDD:275380 7/20 (35%)
LRRCT 294..345 CDD:214507 10/63 (16%)
IG_like 353..435 CDD:214653 18/83 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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