DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and XB982628

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	XP_002933014.2	Gene:	XB982628 / 100493271	XenbaseID:	XB-GENE-982629	Length:	387	Species:	Xenopus tropicalis

Alignment Length:	429	Identity:	103/429 - (24%)
Similarity:	171/429 - (39%)	Gaps:	104/429 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   653 MMNIWPQMHNLSKQLGASMH-------DPWETAINFNEEQLQTQTGGQIATSYMEEYFEEHDVSG 710
            ::|.|..:|.:.:.....:|       ...||.|.::.|.       :..|.||... ...:.|.
Frog    10 VLNKWKNIHCVLRLSFIVLHFLVPLSFKKMETTIGWSYEP-------ENLTIYMVNK-NGSNASA 66

  Fly   711 PATGYGFGTGLFSGMSTEDFQPGSVQCLPMPGP-FLPCADLFDWWTLRCGVWVVFLLSLLGNGTV 774
            |.||                    ||.:....| |:||      :||      |.|:.:.||..:
Frog    67 PFTG--------------------VQLIQSYKPLFIPC------YTL------VVLIGIFGNYLL 99

  Fly   775 VFVLLCSRSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRM-FAIPWQMSV----LCQ 834
            ::|:..:|...:|..|.:.|||.:|..|           .||...|.: :|...|..|    :|.
Frog   100 LYVICRTRKMHNVTNFFIGNLAFSDMLM-----------CATCVPFTLAYAFNPQGWVFGKFMCY 153

  Fly   835 LSGFLAVLSSELSVYTLAVITLERNYAITHAIHLNKRLSLKQAGYIMSVGWVFALIMALMPLVGV 899
            ....:..::..:||:||..|.::|.||..|.  |.||:|:....|::...|:.:     ..|||.
Frog   154 FVFLMQPVTVYVSVFTLTAIAVDRYYATVHP--LKKRISVTTCIYVLMGIWLLS-----CALVGP 211

  Fly   900 S-------DYRK--FAVCLPFETTTGPASLTYVISLMFINGCAFLTLMG-CYLKMYWAIRG---- 950
            :       ::::  |.:|..|........|.|..|.:.|.....|:.:. .|:.:...::.
Frog   212 AIAHTYHVEFQQEGFTICEEFWMGKETERLAYAYSTLIITYILPLSAVSLSYICITVKLKNRVVP 276

  Fly   951 -----SQAWNTNDSRIAK----RMALLVFTDF-LCWSPIAFFSITAIFGLQLISLE---QAKIFT 1002
                 |||   ...|:.|    |:.:||.|.| :||.||..|:|.....:.||:..   ..::|.
Frog   277 GHPTQSQA---EFDRLRKRKIFRLIVLVVTAFGICWLPIHVFNIIRDIDINLINKHYFLHIQLFC 338

  Fly  1003 VFVLPLNSCCNPFLYAIMTKQFKKDCVTLCKHFEESRVV 1041
            .:....:|||||||||.:..:|:.:   |.|.|...|.:
Frog   339 HWFAMSSSCCNPFLYAWLHDRFRSE---LRKMFTFKRKI 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380
		LRR_RI	180..>383	CDD:238064
		leucine-rich repeat	183..204	CDD:275380
		LRR_8	203..263	CDD:290566
		leucine-rich repeat	205..228	CDD:275380
		leucine-rich repeat	229..252	CDD:275380
		LRR_8	252..311	CDD:290566
		leucine-rich repeat	253..276	CDD:275380
		leucine-rich repeat	277..300	CDD:275380
		LRR_8	299..359	CDD:290566
		leucine-rich repeat	301..324	CDD:275380
		leucine-rich repeat	325..348	CDD:275380
		LRR_RI	327..567	CDD:238064
		leucine-rich repeat	349..371	CDD:275380
		LRR_8	370..425	CDD:290566
		leucine-rich repeat	372..393	CDD:275380
		leucine-rich repeat	394..415	CDD:275380
		leucine-rich repeat	418..486	CDD:275380
		leucine-rich repeat	441..464	CDD:275378
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433	34/132 (26%)
		7tm_1	770..1017	CDD:278431	70/278 (25%)
XB982628	XP_002933014.2	7tmA_PrRP_R	79..364	CDD:320516	82/320 (26%)
		TM helix 1	80..106	CDD:320516	10/37 (27%)
		TM helix 2	113..138	CDD:320516	9/35 (26%)
		TM helix 3	152..182	CDD:320516	9/29 (31%)
		TM helix 4	193..214	CDD:320516	5/25 (20%)
		TM helix 5	240..269	CDD:320516	6/28 (21%)
		TM helix 6	289..319	CDD:320516	12/29 (41%)
		TM helix 7	332..357	CDD:320516	10/24 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910