DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and chadl

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:XP_002934783.2 Gene:chadl / 100491048 XenbaseID:XB-GENE-6050564 Length:721 Species:Xenopus tropicalis


Alignment Length:689 Identity:146/689 - (21%)
Similarity:247/689 - (35%) Gaps:215/689 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   143 ICERWLQKHCHCTGSLEVLR--LSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNL 205
            :|:| ..:.|.|    :.:|  ::|....:..||.::|.....|||..|:|..:...:|...|.|
 Frog    18 LCDR-CPRVCIC----DNIRTFVACTNKNLTEVPTSIPQYTQKLDLRGNDLKVIPNGAFLSVPYL 77

  Fly   206 EELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDC 270
            ..|:|...:|..::..|..||.:|..|:|.:..:..:..:||.||:.|..|.|..|.|..:....
 Frog    78 THLSLQKCNIERIEEGALRGLGRLVYLNLGSNKISFIYQESFDGLSSLQQLVLEKNRLEEIKPGA 142

  Fly   271 LGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQI 335
            .|.|..|..|.|..|....:|.....||:.::.:.|.:|::.::::|.|..:|||..|.|..|::
 Frog   143 FGQLGFLNFLHLGDNFLVYLPDMLFQGLQQVKWIRLSNNMINVVSNEAFAALPNLKRLSLDHNEL 207

  Fly   336 MKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPRSMQ--MLD 398
            ..:...||..::.|..|||..|.::.:.|...:::.|::|.:.:..::.::.....||.|  ::|
 Frog   208 QYLPTDALSRMSGLTRLELGWNPMTFISEEAVQMASLKQLFLNNMAIQDLSFKAFERSPQLSLID 272

  Fly   399 MRANPLSTI--------------------------------------------SPGAFRG--MSK 417
            :..|.:.||                                            .||.|||  :..
 Frog   273 LSNNQIRTIQVLAGLEHLNRLNLTGNAIRCDCELRSFKQWADFSKVKVDLFCSGPGHFRGDHLDS 337

  Fly   418 LRKLILSDVRTLRSFPELE------------------AC-------HALEILKLDRAGIQEVPAN 457
            ||.:.|.    ..:|||.:                  :|       |.|    .:...:|::|..
 Frog   338 LRAIDLK----CGNFPEEDYNLPPITPKPEEESSCPRSCDCKPDDKHVL----CENKFLQQIPKR 394

  Fly   458 LCRQTPRLKSLELKTNSLKRIPN--LSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNR 520
            ....|   ..|:|:.|....|..  .|..:::..|.|.|.||.:||...|.|:|.|..|.||:|.
 Frog   395 FPVDT---TLLDLRKNVFNAIHKGAFSEMKNVASLHLQSCQINEIQPGAFAGMKNLVYLYLSHNH 456

  Fly   521 IKALPQDAFQGIP------------------------------------------------KLQL 537
            :.::..:.|:..|                                                ||..
 Frog   457 LSSIDPEVFRDAPMIGYLYLDHNRFTRLSKGTFKFLPNLFSLHMQYNSISSLSDNFMSGADKLHW 521

  Fly   538 LDLEGNEISYIHKEAFSGFTALEDLNLGNNIFPELPESGLRAL---------------------- 580
            :.:.||.|:||...||.....||.|:|..|:..|:|...::.|                      
 Frog   522 VYMTGNNINYIASSAFKNNKDLEKLHLDENLLMEVPTQAIKGLPLLNELRLSKNLIRSIGNGAFL 586

  Fly   581 ---------------------------------LHLKTFNNPKLREFPPPDTFPRIQTL-ILSYA 611
                                             |||   :|.||:..|....|..::.: :.:..
 Frog   587 PVARSLQHLYLNDLGLEQISSGGFSGLGQGIKSLHL---DNNKLQNIPNMKPFTGLEVINLANNP 648

  Fly   612 YHC-CAFLPL--------------VAMSSQKKTSQVQEA 635
            :|| |..|||              .|..|..|..:|:.|
 Frog   649 FHCDCRLLPLHKWINSLNLKVGATCAAPSSAKGQKVRNA 687

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 4/22 (18%)
LRR_RI 180..>383 CDD:238064 55/202 (27%)
leucine-rich repeat 183..204 CDD:275380 6/20 (30%)
LRR_8 203..263 CDD:290566 19/59 (32%)
leucine-rich repeat 205..228 CDD:275380 7/22 (32%)
leucine-rich repeat 229..252 CDD:275380 7/22 (32%)
LRR_8 252..311 CDD:290566 16/58 (28%)
leucine-rich repeat 253..276 CDD:275380 7/22 (32%)
leucine-rich repeat 277..300 CDD:275380 7/22 (32%)
LRR_8 299..359 CDD:290566 17/59 (29%)
leucine-rich repeat 301..324 CDD:275380 4/22 (18%)
leucine-rich repeat 325..348 CDD:275380 6/22 (27%)
LRR_RI 327..567 CDD:238064 72/362 (20%)
leucine-rich repeat 349..371 CDD:275380 6/21 (29%)
LRR_8 370..425 CDD:290566 17/102 (17%)
leucine-rich repeat 372..393 CDD:275380 2/20 (10%)
leucine-rich repeat 394..415 CDD:275380 10/68 (15%)
leucine-rich repeat 418..486 CDD:275380 17/94 (18%)
leucine-rich repeat 441..464 CDD:275378 4/22 (18%)
LRR_8 487..545 CDD:290566 21/105 (20%)
leucine-rich repeat 487..510 CDD:275380 9/22 (41%)
leucine-rich repeat 511..534 CDD:275380 7/70 (10%)
LRR_8 533..589 CDD:290566 21/158 (13%)
leucine-rich repeat 535..558 CDD:275380 8/22 (36%)
leucine-rich repeat 559..580 CDD:275380 7/20 (35%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
chadlXP_002934783.2 PPP1R42 37..232 CDD:411060 56/194 (29%)
leucine-rich repeat 53..76 CDD:275380 6/22 (27%)
leucine-rich repeat 77..100 CDD:275380 7/22 (32%)
leucine-rich repeat 101..124 CDD:275380 7/22 (32%)
leucine-rich repeat 125..148 CDD:275380 7/22 (32%)
leucine-rich repeat 149..172 CDD:275380 7/22 (32%)
leucine-rich repeat 173..196 CDD:275380 4/22 (18%)
leucine-rich repeat 197..220 CDD:275380 6/22 (27%)
leucine-rich repeat 221..243 CDD:275380 6/21 (29%)
leucine-rich repeat 244..267 CDD:275380 4/22 (18%)
leucine-rich repeat 268..287 CDD:275380 4/18 (22%)
PCC 272..>346 CDD:188093 12/77 (16%)
leucine-rich repeat 290..337 CDD:275380 5/46 (11%)
inl_like_NEAT_1 <359..>647 CDD:411101 53/297 (18%)
leucine-rich repeat 399..422 CDD:275380 6/25 (24%)
LRR_8 422..481 CDD:404697 17/58 (29%)
leucine-rich repeat 423..446 CDD:275380 9/22 (41%)
leucine-rich repeat 447..470 CDD:275380 6/22 (27%)
leucine-rich repeat 471..494 CDD:275380 0/22 (0%)
leucine-rich repeat 495..518 CDD:275380 0/22 (0%)
leucine-rich repeat 519..542 CDD:275380 8/22 (36%)
leucine-rich repeat 543..566 CDD:275380 8/22 (36%)
leucine-rich repeat 567..591 CDD:275380 0/23 (0%)
leucine-rich repeat 592..615 CDD:275380 0/22 (0%)
leucine-rich repeat 617..639 CDD:275380 8/24 (33%)
leucine-rich repeat 640..651 CDD:275378 0/10 (0%)
LRRCT 647..693 CDD:214507 11/41 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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