DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and lrrd1

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:XP_002934640.2 Gene:lrrd1 / 100490254 XenbaseID:XB-GENE-985410 Length:757 Species:Xenopus tropicalis


Alignment Length:543 Identity:147/543 - (27%)
Similarity:231/543 - (42%) Gaps:133/543 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   176 NLPNEVVVLDLGNNNLTKLEANS---------FFMAPNLEELTLSDNSIINMDPNAFYGLAKLKR 231
            |:|..|   ..|..::|.:..||         .|...||:.|.||:|.:.:: |.:...|:||:.
 Frog    29 NMPRTV---PSGTGSITSINLNSKELTEIPPDVFRCTNLQCLLLSNNFMTHL-PTSLCHLSKLEI 89

  Fly   232 LSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGD----------------------CLGHL 274
            |||:...|.||||: ...|:|||:|.:|.|.:..|..:                      |||.|
 Frog    90 LSLEGNALVSLPPE-ICSLSQLTALNVNHNQIAVLPHEISGLKNIKQLFANNNKLSQLPPCLGDL 153

  Fly   275 QKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKI- 338
            ..|:.|.:.||....:| ::.|.|:.|..|||..|.::.:....| |:..|:.|.|..|||..: 
 Frog   154 TTLQVLCISGNSMKTLP-DSTASLKNLHVLNLDGNQISALPKAVF-RLSQLVKLCLSGNQIKSLP 216

  Fly   339 -SAGALK--------------------NLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRL 382
             ..|.||                    |||:|:.|.||||.::::.:.|..|.||:.|||.:|.|
 Frog   217 KEIGDLKNLRELSLSSNQLTFLPVQLYNLTSLEELTLDDNKLTAISDKLQNLKQLKVLSIANNLL 281

  Fly   383 RWINDT------------------ELP------RSMQMLDMRANPLSTISPGAFRGMSKLRKLIL 423
            ..|.:.                  .||      |:::.|.:..|.|..: |.....::.|..::.
 Frog   282 TDITEKVCWCPAIECLKLNGNQMYRLPTKIHNLRNLKELHIERNALEML-PDQLAHLNNLSVIVC 345

  Fly   424 SDVRTLRSFPELEACHALEILKLDRAG--IQEVPANLCRQTP----------------------R 464
            ::...|....||:.|:  :|.|||.:|  :.|||..|...|.                      :
 Frog   346 ANNNLLWIPIELKNCN--QITKLDLSGNKLSEVPQALSSMTSLLYLNLNQNEIHEIANSIIHNRK 408

  Fly   465 LKSLELKTNSLKRIPNLSSC--RDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQD 527
            |:.|||..|.| .:.::..|  .:|..||||.|:|..:. ...:.|:.|::|||..|:.:..|.:
 Frog   409 LEHLELSGNKL-TVFSVHFCGLHNLAYLDLSRNEINSVP-SAISNLESLSELLLHSNKFRRFPIE 471

  Fly   528 AFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDL---NLGNNIFPELPESGLRALLHLKTFNNP 589
             ...:..||.:||.||:|..:.    ||.:.||.|   ||.||.|...|    |.|..:.:....
 Frog   472 -LCALKSLQKIDLSGNQIETVP----SGISLLEGLRYVNLSNNSFKVFP----RELFSVSSLETL 527

  Fly   590 KLRE------FPPPDTFPRIQTL 606
            |:.:      ...||...:::.|
 Frog   528 KISQKDGRKLISLPDELSKLKNL 550

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 1/2 (50%)
LRR_RI 180..>383 CDD:238064 76/255 (30%)
leucine-rich repeat 183..204 CDD:275380 5/29 (17%)
LRR_8 203..263 CDD:290566 25/59 (42%)
leucine-rich repeat 205..228 CDD:275380 7/22 (32%)
leucine-rich repeat 229..252 CDD:275380 10/22 (45%)
LRR_8 252..311 CDD:290566 23/80 (29%)
leucine-rich repeat 253..276 CDD:275380 10/44 (23%)
leucine-rich repeat 277..300 CDD:275380 7/22 (32%)
LRR_8 299..359 CDD:290566 25/81 (31%)
leucine-rich repeat 301..324 CDD:275380 7/22 (32%)
leucine-rich repeat 325..348 CDD:275380 11/44 (25%)
LRR_RI 327..567 CDD:238064 84/314 (27%)
leucine-rich repeat 349..371 CDD:275380 8/21 (38%)
LRR_8 370..425 CDD:290566 16/78 (21%)
leucine-rich repeat 372..393 CDD:275380 9/44 (20%)
leucine-rich repeat 394..415 CDD:275380 4/20 (20%)
leucine-rich repeat 418..486 CDD:275380 22/93 (24%)
leucine-rich repeat 441..464 CDD:275378 10/46 (22%)
LRR_8 487..545 CDD:290566 20/57 (35%)
leucine-rich repeat 487..510 CDD:275380 8/22 (36%)
leucine-rich repeat 511..534 CDD:275380 6/22 (27%)
LRR_8 533..589 CDD:290566 20/58 (34%)
leucine-rich repeat 535..558 CDD:275380 9/22 (41%)
leucine-rich repeat 559..580 CDD:275380 10/23 (43%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
lrrd1XP_002934640.2 PLN00113 41..>611 CDD:215061 143/528 (27%)
leucine-rich repeat 42..63 CDD:275380 4/20 (20%)
leucine-rich repeat 64..86 CDD:275380 7/22 (32%)
leucine-rich repeat 87..109 CDD:275380 10/22 (45%)
leucine-rich repeat 110..132 CDD:275380 6/21 (29%)
leucine-rich repeat 133..155 CDD:275380 4/21 (19%)
leucine-rich repeat 156..178 CDD:275380 7/22 (32%)
leucine-rich repeat 179..201 CDD:275380 7/22 (32%)
leucine-rich repeat 202..224 CDD:275380 8/21 (38%)
leucine-rich repeat 225..247 CDD:275380 2/21 (10%)
leucine-rich repeat 248..270 CDD:275380 8/21 (38%)
leucine-rich repeat 271..316 CDD:275380 9/44 (20%)
leucine-rich repeat 340..385 CDD:275380 14/46 (30%)
leucine-rich repeat 386..408 CDD:275380 0/21 (0%)
leucine-rich repeat 409..431 CDD:275380 7/22 (32%)
leucine-rich repeat 478..500 CDD:275380 10/25 (40%)
leucine-rich repeat 501..520 CDD:275380 9/22 (41%)
leucine-rich repeat 550..572 CDD:275380 1/1 (100%)
leucine-rich repeat 573..595 CDD:275380
leucine-rich repeat 596..618 CDD:275380
Death 664..744 CDD:260017
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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