DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and si:dkey-182i3.11

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:XP_021322095.1 Gene:si:dkey-182i3.11 / 100334238 ZFINID:ZDB-GENE-121214-258 Length:710 Species:Danio rerio


Alignment Length:654 Identity:176/654 - (26%)
Similarity:267/654 - (40%) Gaps:166/654 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 CHCTGSLEVLRLSCRGIGILAVPVNLPN---------------------EVVVLDLGNNNLTKLE 195
            |.|   ::|..::|....:|..| .|||                     |:.|||| ..|:..|.
Zfish    59 CSC---VDVDIVTCWNTNLLEFP-PLPNGTKHFYATRNKIQALPNETFHELRVLDL-TKNVFNLS 118

  Fly   196 ANSFFMA-PNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLN 259
            .|:.:.: ..|..|.|..|.:..:.|..|.||..|:.|.|.|..:||||.....||..|.:|.||
Zfish   119 LNTNWQSVRGLTHLHLGGNRLRALTPRQFEGLLNLQVLDLSNNAIKSLPQMFLYGLINLQTLNLN 183

  Fly   260 GNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPN 324
            .|.::||.                    |.:    |.|...|..|.|..|::.:|....|.....
Zfish   184 INQILSLS--------------------YGV----LEGPLALTDLQLRDNMIDMIEMNVFENCTY 224

  Fly   325 LIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPE-GLSKLSQLQELSITSNRLRWINDT 388
            |..|.|.:|::..:..|:.|..|.|..|:|..|.::.:|. .|.:.|.|..|.:..|.:..|.|.
Zfish   225 LAKLYLSKNKLKSVGNGSFKGATGLNHLDLGLNGLAGIPTIVLQETSNLTSLYLQKNDITSIPDN 289

  Fly   389 ELPR--SMQMLDMRANPLSTISPGAFRGMSKLRKLILS--DVRTLRS--FPELEACHALEILKLD 447
            ....  |::.||:..|.|.:||.|:||.:|:|..|.||  .::||..  |.:|   ..||.|.|.
Zfish   290 VFSEILSLKHLDLSYNGLVSISNGSFRSLSQLVYLDLSFNQLQTLTQHVFEDL---GKLENLNLY 351

  Fly   448 RAGIQEVPANLCRQTPRLKSLELKTNSLKRIP-----NLSSCRDLRL------------------ 489
            ...:..:|.|:.:....||.|:|.:|::..||     .||:.:||:|                  
Zfish   352 HNKLTSLPNNMFKNLTMLKELQLDSNNISVIPPDLFHPLSALKDLQLDNNHISKLHSHTFKKLRQ 416

  Fly   490 ---LDLSSNQIEKIQGKPFN-GLKQLN-------------------------------------- 512
               ||:|||.:.||....|: .||:||                                      
Zfish   417 LKQLDISSNDLTKIPNHLFHKNLKELNLENNHISFISKFSFKNLHRLQSLKLSHNNLSKLYRELL 481

  Fly   513 -------DLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNIFP 570
                   :|||:.|:|:.:|...|:|:..|::|||..|::.:|..:||:..:||:||:|..|...
Zfish   482 TNLTRLRELLLNENQIETIPVGFFKGLENLRVLDLSNNKMHFILPDAFNDLSALKDLDLSFNFLH 546

  Fly   571 ELPE---SGLRAL--LHLKTFNNPKLREFPPP--DTFPRIQTLILSYAY----HCCAFLPLVAMS 624
            .|||   :.||.|  |||:   |.|||..|..  .....::.|.|...|    |...|..||.:.
Zfish   547 NLPEDIFASLRNLTKLHLQ---NNKLRYLPSRLFSALVGLEELHLDRNYIQRIHPTQFEGLVKLH 608

  Fly   625 S-QKKTSQ---VQEAVLFP----SDAEFDMTLWNNSMMNIW--PQMHNLSKQL---------GAS 670
            . ..|::|   :::..|.|    .....|...|:.|.:.|.  .|..|.:.||         |.:
Zfish   609 ELDMKSNQLRSMEDGTLMPLRKLKRIHLDGNPWDCSTVVILYISQWFNNNTQLVKTTPMCSSGQN 673

  Fly   671 MHDP 674
            :.:|
Zfish   674 LSNP 677

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380 5/20 (25%)
LRR_RI 180..>383 CDD:238064 59/204 (29%)
leucine-rich repeat 183..204 CDD:275380 7/21 (33%)
LRR_8 203..263 CDD:290566 23/59 (39%)
leucine-rich repeat 205..228 CDD:275380 8/22 (36%)
leucine-rich repeat 229..252 CDD:275380 10/22 (45%)
LRR_8 252..311 CDD:290566 14/58 (24%)
leucine-rich repeat 253..276 CDD:275380 7/22 (32%)
leucine-rich repeat 277..300 CDD:275380 3/22 (14%)
LRR_8 299..359 CDD:290566 17/59 (29%)
leucine-rich repeat 301..324 CDD:275380 6/22 (27%)
leucine-rich repeat 325..348 CDD:275380 6/22 (27%)
LRR_RI 327..567 CDD:238064 88/318 (28%)
leucine-rich repeat 349..371 CDD:275380 6/22 (27%)
LRR_8 370..425 CDD:290566 21/58 (36%)
leucine-rich repeat 372..393 CDD:275380 5/22 (23%)
leucine-rich repeat 394..415 CDD:275380 9/20 (45%)
leucine-rich repeat 418..486 CDD:275380 23/76 (30%)
leucine-rich repeat 441..464 CDD:275378 6/22 (27%)
LRR_8 487..545 CDD:290566 27/124 (22%)
leucine-rich repeat 487..510 CDD:275380 11/44 (25%)
leucine-rich repeat 511..534 CDD:275380 10/67 (15%)
LRR_8 533..589 CDD:290566 23/60 (38%)
leucine-rich repeat 535..558 CDD:275380 8/22 (36%)
leucine-rich repeat 559..580 CDD:275380 10/23 (43%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
si:dkey-182i3.11XP_021322095.1 PLN00113 97..>617 CDD:331614 154/550 (28%)
leucine-rich repeat 129..152 CDD:275380 8/22 (36%)
leucine-rich repeat 153..176 CDD:275380 10/22 (45%)
leucine-rich repeat 177..200 CDD:275380 10/46 (22%)
leucine-rich repeat 201..224 CDD:275380 6/22 (27%)
leucine-rich repeat 225..248 CDD:275380 6/22 (27%)
leucine-rich repeat 249..272 CDD:275380 6/22 (27%)
leucine-rich repeat 273..296 CDD:275380 5/22 (23%)
leucine-rich repeat 297..320 CDD:275380 9/22 (41%)
leucine-rich repeat 321..344 CDD:275380 8/25 (32%)
leucine-rich repeat 345..368 CDD:275380 6/22 (27%)
leucine-rich repeat 369..392 CDD:275380 8/22 (36%)
leucine-rich repeat 393..438 CDD:275380 11/44 (25%)
leucine-rich repeat 417..436 CDD:275380 7/18 (39%)
leucine-rich repeat 439..462 CDD:275380 4/22 (18%)
leucine-rich repeat 463..486 CDD:275380 0/22 (0%)
leucine-rich repeat 487..510 CDD:275380 8/22 (36%)
leucine-rich repeat 511..534 CDD:275380 8/22 (36%)
leucine-rich repeat 535..558 CDD:275380 9/22 (41%)
leucine-rich repeat 559..582 CDD:275380 9/25 (36%)
leucine-rich repeat 583..606 CDD:275380 6/22 (27%)
leucine-rich repeat 607..628 CDD:275380 3/20 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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