DRSC/TRiP Functional Genomics Resources

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Protein Alignment rk and drc3

DIOPT Version :9

Sequence 1:NP_476702.1 Gene:rk / 34819 FlyBaseID:FBgn0003255 Length:1360 Species:Drosophila melanogaster
Sequence 2:NP_001123832.1 Gene:drc3 / 100170587 XenbaseID:XB-GENE-1003585 Length:522 Species:Xenopus tropicalis


Alignment Length:413 Identity:98/413 - (23%)
Similarity:165/413 - (39%) Gaps:99/413 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   201 MAPNLEELTLSDNSIINMDPNAFYG-LAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALV 264
            |.||:.:..:..|::....|....| :|||:.:..::                ::||:|:...::
 Frog     8 MEPNVIDDDMLRNAVEEQGPKEEAGRIAKLEGIDFKH----------------VSSLRLDFKNIL 56

  Fly   265 SLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLL 329
            .:|.  |.....|..|:|:.|:..:|     :||.||                     .:|:.|.
 Frog    57 KIDN--LWQFHSLTKLQLDNNIIEKI-----SGLDTL---------------------VHLVWLD 93

  Fly   330 LKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPR-- 392
            |..|.|..|.  .||.||.|:.|.|.:|.| |:.|.:..||.||.||:.:|.|..:.:....|  
 Frog    94 LSFNNIEVIE--GLKALTKLEDLSLYNNRI-SVVENMDTLSNLQVLSLGNNNLTSLENLIYLRKF 155

  Fly   393 -SMQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPA 456
             .::.|.:..||||..........:.|..|...|.|.|.     |....:..:|. :..|.::..
 Frog   156 KQLRTLSLAGNPLSEDDQYKLFIAAHLPNLAYLDFRLLN-----ENIREMATMKY-QYSIDDITH 214

  Fly   457 NLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDL-SSNQIEKIQGKPF--------------- 505
            |..::..:.:..|.|.               |.||| .:..:|.:.| ||               
 Frog   215 NENQEKRKQEEEEQKQ---------------RELDLHKAAYVENLNG-PFLFESMYADDADGTKL 263

  Fly   506 NGLKQLNDLLLSYNRIKALP--QDAFQ-GIPKLQLLDLEGNEISYIHKEAF-----SGFTALEDL 562
            :||..:.:|:.|| |.|.:.  |:.|: |:.:.:..:.|..|.:...:||.     .|...:::|
 Frog   264 SGLPGVAELMDSY-RSKCIEICQNIFEYGMKQHEKREAEAFEFNECMQEAIRENQEQGAKKIQEL 327

  Fly   563 NLGNN-IFPELPESGLRALLHLK 584
            ...|: |..||.:||.:..|.||
 Frog   328 TEKNSEILNELSQSGNQDFLDLK 350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rkNP_476702.1 leucine-rich repeat 158..179 CDD:275380
LRR_RI 180..>383 CDD:238064 47/182 (26%)
leucine-rich repeat 183..204 CDD:275380 1/2 (50%)
LRR_8 203..263 CDD:290566 11/60 (18%)
leucine-rich repeat 205..228 CDD:275380 3/23 (13%)
leucine-rich repeat 229..252 CDD:275380 1/22 (5%)
LRR_8 252..311 CDD:290566 14/58 (24%)
leucine-rich repeat 253..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..300 CDD:275380 7/22 (32%)
LRR_8 299..359 CDD:290566 16/59 (27%)
leucine-rich repeat 301..324 CDD:275380 1/22 (5%)
leucine-rich repeat 325..348 CDD:275380 9/22 (41%)
LRR_RI 327..567 CDD:238064 65/266 (24%)
leucine-rich repeat 349..371 CDD:275380 8/21 (38%)
LRR_8 370..425 CDD:290566 15/57 (26%)
leucine-rich repeat 372..393 CDD:275380 7/23 (30%)
leucine-rich repeat 394..415 CDD:275380 5/20 (25%)
leucine-rich repeat 418..486 CDD:275380 11/67 (16%)
leucine-rich repeat 441..464 CDD:275378 3/22 (14%)
LRR_8 487..545 CDD:290566 19/76 (25%)
leucine-rich repeat 487..510 CDD:275380 10/38 (26%)
leucine-rich repeat 511..534 CDD:275380 8/25 (32%)
LRR_8 533..589 CDD:290566 15/58 (26%)
leucine-rich repeat 535..558 CDD:275380 5/27 (19%)
leucine-rich repeat 559..580 CDD:275380 7/21 (33%)
7tm_4 764..>892 CDD:304433
7tm_1 770..1017 CDD:278431
drc3NP_001123832.1 leucine-rich repeat 47..66 CDD:275380 5/20 (25%)
LRR_RI <60..211 CDD:238064 49/187 (26%)
leucine-rich repeat 67..88 CDD:275378 9/46 (20%)
LRR_8 88..143 CDD:290566 24/57 (42%)
leucine-rich repeat 89..110 CDD:275378 9/22 (41%)
LRR_4 109..149 CDD:289563 16/40 (40%)
leucine-rich repeat 111..132 CDD:275378 8/21 (38%)
leucine-rich repeat 133..157 CDD:275378 7/23 (30%)
leucine-rich repeat 158..169 CDD:275378 3/10 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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