DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rk and XB964897

DIOPT Version :9

Sequence 1:	NP_476702.1	Gene:	rk / 34819	FlyBaseID:	FBgn0003255	Length:	1360	Species:	Drosophila melanogaster
Sequence 2:	NP_001123809.1	Gene:	XB964897 / 100170560	XenbaseID:	XB-GENE-964898	Length:	798	Species:	Xenopus tropicalis

Alignment Length:	480	Identity:	127/480 - (26%)
Similarity:	203/480 - (42%)	Gaps:	131/480 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ETKENPAPDMQNS--------QEQEPY------VHLQH-----LQQQQQQNPQTVQQLS------ 75
            ||..|..||::|.        .:.:|.      |.|..     |:|....|..||::|.
Frog   349 ETGINDIPDVKNDLAFLFHMIDQYDPLYSKRFAVFLSEASENKLKQLNLNNEWTVEKLRLKLQTN 413

  Fly    76 --------------------QITVNRTSKSASVTPTGIRENVMLPSADPEKEAQI--LYEKSL-- 116
                                :||..::.|..|:      .|||:|:|    .||:  |.|.||
Frog   414 ASNRLELHLLKLPGLPDTVFEITELQSLKLESI------PNVMIPAA----IAQLNNLQELSLWT 468

  Fly   117 --QEYHGSQLSTASTATDVIAGKRTLHSICERWL------QKHCHCTGSLEVLRLSCRGIGILAV 173
              .:.|.:.|:..         |..:||:..:::      |..|. .||||.|.|:  |:....:
Frog   469 CPAKIHSAALAFL---------KENVHSLSVKFVGSPHIPQWMCD-LGSLEELNLT--GLFTPEI 521

  Fly   174 PVNLPN----------EVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAK 228
            ..:.||          .:|:    |:|||.:...:..::..|::|::.:|.|..:..|:...:|.
Frog   522 SKHFPNYSFKKLKSLKHLVI----NSNLTSIPQYAVDISAQLQKLSIDNNEIKLVTRNSLKNMAN 582

  Fly   229 LKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSL-DGDCLGHLQKLRTLRLEGNLFYRIPT 292
            |..|.|.||.|..:|...|..|| |..|.|..|.|.|: :.....:||||..|:|..|...:||.
Frog   583 LMTLELVNCKLDQIPNSIFSLLA-LKELDLKNNNLKSIQEIASFQNLQKLSILKLWHNSITKIPD 646

  Fly   293 NALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDN 357
            : ::.|..||.|.:..|     |..|   :|:.:.|..|                 |:.|||.:|
Frog   647 H-ISKLANLEQLYISHN-----NIGD---LPHDLFLCCK-----------------LRHLELSNN 685

  Fly   358 LISSLPEGLSKLSQLQELSITSNRLRWINDTEL--PRSMQMLDMRANPLSTISPGAFRGMSKLRK 420
            .|.|:|..:..||.|:..|::.||:..|.| ||  .:.::.|::|.|.::|:||    .:..|.:
Frog   686 NIRSIPHIIRNLSNLKYFSVSYNRIETIPD-ELYFCQKLETLNLRHNNINTLSP----NIGNLAQ 745

  Fly   421 LILSDVR--TLRSFP-ELEACHALE 442
            |...||:  .:.|.| ||.:|.||:
Frog   746 LSCLDVKENPIGSLPLELGSCQALK 770

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rk	NP_476702.1	leucine-rich repeat	158..179	CDD:275380	5/20 (25%)
		LRR_RI	180..>383	CDD:238064	60/203 (30%)
		leucine-rich repeat	183..204	CDD:275380	4/20 (20%)
		LRR_8	203..263	CDD:290566	20/59 (34%)
		leucine-rich repeat	205..228	CDD:275380	5/22 (23%)
		leucine-rich repeat	229..252	CDD:275380	9/22 (41%)
		LRR_8	252..311	CDD:290566	20/59 (34%)
		leucine-rich repeat	253..276	CDD:275380	7/23 (30%)
		leucine-rich repeat	277..300	CDD:275380	7/22 (32%)
		LRR_8	299..359	CDD:290566	14/59 (24%)
		leucine-rich repeat	301..324	CDD:275380	6/22 (27%)
		leucine-rich repeat	325..348	CDD:275380	2/22 (9%)
		LRR_RI	327..567	CDD:238064	37/121 (31%)
		leucine-rich repeat	349..371	CDD:275380	9/21 (43%)
		LRR_8	370..425	CDD:290566	17/56 (30%)
		leucine-rich repeat	372..393	CDD:275380	8/22 (36%)
		leucine-rich repeat	394..415	CDD:275380	6/20 (30%)
		leucine-rich repeat	418..486	CDD:275380	11/28 (39%)
		leucine-rich repeat	441..464	CDD:275378	1/2 (50%)
		LRR_8	487..545	CDD:290566
		leucine-rich repeat	487..510	CDD:275380
		leucine-rich repeat	511..534	CDD:275380
		LRR_8	533..589	CDD:290566
		leucine-rich repeat	535..558	CDD:275380
		leucine-rich repeat	559..580	CDD:275380
		7tm_4	764..>892	CDD:304433
		7tm_1	770..1017	CDD:278431
XB964897	NP_001123809.1	leucine-rich repeat	606..630	CDD:275380	7/23 (30%)
		leucine-rich repeat	631..653	CDD:275380	7/22 (32%)
		leucine-rich repeat	654..676	CDD:275380	8/29 (28%)
		LRR_8	676..733	CDD:290566	22/74 (30%)
		leucine-rich repeat	677..699	CDD:275380	9/21 (43%)
		leucine-rich repeat	700..722	CDD:275380	8/22 (36%)
		leucine-rich repeat	723..745	CDD:275380	7/25 (28%)
		leucine-rich repeat	746..766	CDD:275380	7/19 (37%)
		Pannexin_like	1..330	CDD:289311
		leucine-rich repeat	392..437	CDD:275380	7/44 (16%)
		leucine-rich repeat	488..504	CDD:275380	1/15 (7%)
		LRR_RI	534..767	CDD:238064	78/268 (29%)
		leucine-rich repeat	536..558	CDD:275380	5/25 (20%)
		LRR_8	558..616	CDD:290566	20/58 (34%)
		leucine-rich repeat	559..582	CDD:275380	5/22 (23%)
		leucine-rich repeat	583..605	CDD:275380	8/21 (38%)
		LRR_8	606..664	CDD:290566	20/63 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910