Protein Alignment NimC2 and Pear1

DIOPT Version :9

• Sequence 1: NP_001285922.1
• Gene: NimC2 / 34818
• FlyBaseID: FBgn0028939
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001027585.1
• Gene: Pear1 / 73182
• MGIID: 1920432
• Length: 1034
• Species: Mus musculus
• Alignment Length: 833
• Identity: 195/833 - (23%)
• Similarity: 269/833 - (32%)
• Gaps: 315/833 - (37%)

  Fly    65 CCDGYIRDENNECVPLCNDCGASGKCLLPNVCLCGKGYVSRKDHGHCEPECSESCVNGKCVAPDE 129
            ||.||. :....|||||......|:|:.||.|.|..|:..    |.|..||:......:|   |:
Mouse    88 CCRGYY-ESRGACVPLCAQECVHGRCVAPNQCQCAPGWRG----GDCSSECAPGMWGPQC---DK 144

  Fly   130 -CECLAGHRFVNGSQTACEPICVEDCANGRCLETGKCLCNNGYQRDEKLKKCV-----PICQ-DA 187
             |.|        |:.::|:|            ::|.|.|.:|.|....|:.|.     |.|| |.
Mouse   145 FCHC--------GNNSSCDP------------KSGTCFCPSGLQPPNCLQPCPAGHYGPACQFDC 189

  Fly   188 -CYHGDCVAPNE--CRCHPGHEQRLGVPWICDPICSSGCANGYCQGAEVCACKMGYAHKDNTLAS 249
             ||...| .|.:  |.|.||   |.|..  |:..||.|....:|  .....|:.|...:.:..:.
Mouse   190 QCYGASC-DPQDGACFCPPG---RAGPS--CNVPCSQGTDGFFC--PRTYPCQNGGVPQGSQGSC 246

  Fly   250 GCEP-----VCNPPCTNG----TCIS-------------PGHCACSEGHVFAEGSR--------- 283
            .|.|     :|:.||..|    .|..             .|.|.|:.|::   |.|
Mouse   247 SCPPGWMGVICSLPCPEGFHGPNCTQECRCHNGGLCDRFTGQCHCAPGYI---GDRCQEECPVGR 308

  Fly   284 --------HECVPSCR----SG---CENGY------------------CSSP------------- 302
                    .:|.|..|    :|   ||:|:                  |..|
Mouse   309 FGQDCAETCDCAPGARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQEPCTCDPEHSLSCHP 373

  Fly   303 --GRCECHEGFEKTSPHRCSPTC-----RPGCGQNSRC-------AAPDTCACDVGYVFVNGSTT 353
              |.|.|..|:   :...|:.:|     .|||.::..|       |....|.|..||     :..
Mouse   374 MHGECSCQPGW---AGLHCNESCPQDTHGPGCQEHCLCLHGGLCLADSGLCRCAPGY-----TGP 430

  Fly   354 ECEPFCPR-----------NCRNGICSSP--GVCTCLEGFQ----------ALLSFYCIPVCSKT 395
            .|...||.           :|.|.|..||  |.|.|.||:|          ....|.|...|.
Mouse   431 HCANLCPPDTYGINCSSRCSCENAIACSPIDGTCICKEGWQRGNCSVPCPLGTWGFNCNASCQ-- 493

  Fly   396 CIHGSCVAP--NECRCFTGYR--------PNPSLG---ANVCEPICSQGC--VHGFCIAPEICQC 445
            |.|....:|  ..|.|..|:.        |....|   |:||:...|.||  |||      .|:|
Mouse   494 CAHDGVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASVCDCDHSDGCDPVHG------QCRC 552

  Fly   446 DLGFIKRWATGTCEPHCPQKCVNSHCLGSGVCRCYEGYKLRPGSTSICDPE-----CQPGCRNGT 505
            ..|    |....|...||:....::|  |..|.|..|        ..|..|     |.||.|..:
Mouse   553 QAG----WMGTRCHLPCPEGFWGANC--SNTCTCKNG--------GTCVSENGNCVCAPGFRGPS 603

  Fly   506 CVEP--------------------------NSCACFAGYEDTKVPYECVPSCRP----------- 533
            |..|                          .:|:|.||:...    :|..:|.|
Mouse   604 CQRPCPPGRYGKRCVQCKCNNNHSSCHPSDGTCSCLAGWTGP----DCSEACPPGHWGLKCSQLC 664

  Fly   534 RCENGRCSSP--GHCECDPGHVVTNSSEPNSCRPQ-----CQE--QCINAECVAPE--KCACLPR 587
            :|.:|....|  |.|.|.||....|..|  .|.|:     |.:  ||...|...||  .|.|.|.
Mouse   665 QCHHGGTCHPQDGSCICTPGWTGPNCLE--GCPPRMFGVNCSQLCQCDLGEMCHPETGACVCPPG 727

  Fly   588 YRFLPDSSTECEPICSKGCLSGQE--CVAPDTCAGFESLISPTTGKHLAFHWSMFVLAILLCLAL 650
            :     |..:|:       :..||  .:.|         .||.|...|.   ::..:|:|..|.:
Mouse   728 H-----SGADCK-------MGSQESFTIMP---------TSPVTHNSLG---AVIGIAVLGTLVV 768

  Fly   651 VMIPLLV-LREMQRRRRNG---------------------DKQSSRLIENPSY 681
            .:|.|.: .|:.|:.:.:.                     ....|....||||
Mouse   769 ALIALFIGYRQWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPSY 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC2	NP_001285922.1	None
Pear1	NP_001027585.1	EMI	25..93	CDD:284877	3/4 (75%)
		EGF_CA	535..580	CDD:304395	17/56 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	823..883
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	925..1034

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810