DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC2 and Esm1

DIOPT Version :9

Sequence 1:	NP_001285922.1	Gene:	NimC2 / 34818	FlyBaseID:	FBgn0028939	Length:	701	Species:	Drosophila melanogaster
Sequence 2:	NP_076101.1	Gene:	Esm1 / 71690	MGIID:	1918940	Length:	184	Species:	Mus musculus

Alignment Length:	176	Identity:	36/176 - (20%)
Similarity:	49/176 - (27%)	Gaps:	64/176 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLLFLVLL---------SGLQVQGCVKQAQVVKMRGTLVTMRKHQNSANCTTNCGPLVGRTRTET 57
            |||...||         |......|.:.....:.|.:|...|...:...|...|....|.|...|
Mouse     4 LLLLTTLLVPLHLGMAWSAKYAVDCPEHCDKTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRT 68

  Fly    58 YLGFTDVCCDGYIR-------DENNECVPLCNDCGASGKCLLPNVCLCGKGYVSRKDHGHCEPEC 115
            ..|...|.|...::       |:..:...:|.||                      .:|....||
Mouse    69 VSGMDGVKCGPGLKCHFYSEEDDFGDEFGICKDC----------------------PYGTFGMEC 111

  Fly   116 SESCVNGKCVAPDECECLAGHRFVNGSQTACEPICVEDCANGRCLE 161
            .|:           |.|.:|             ||  |...||||:
Mouse   112 KET-----------CNCQSG-------------IC--DRVTGRCLD 131

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC2	NP_001285922.1	None
Esm1	NP_076101.1	IGFBP	28..83	CDD:278641	12/54 (22%)
Esm1	NP_076101.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..184
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900