Protein Alignment NimC2 and megf10

DIOPT Version :10

• Sequence 1: NP_788047.1
• Gene: NimC2 / 34818
• FlyBaseID: FBgn0028939
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: NP_001410717.1
• Gene: megf10 / 564571
• ZFINID: ZDB-GENE-080506-1
• Length: 1120
• Species: Danio rerio
• Alignment Length: 893
• Identity: 215/893 - (24%)
• Similarity: 298/893 - (33%)
• Gaps: 336/893 - (37%)

  Fly    65 CCDGYIRDENNECVPLCNDCGASGKCLLPNVCLCGKGY-----VSRKDHGHCEPECSESC----- 119
            ||.|:. :..:.|||.|.:....|:|:.||.|.|..|:     .|..|..|..|.||..|
Zfish    91 CCPGFY-ESGDICVPHCAEKCVHGRCVAPNTCQCEPGWGGADCSSACDRDHWGPHCSSRCQCKNE 154

  Fly   120 -----VNGKCV-APD----ECECLAGH-RFVNGSQTACEPICVEDCANGRCLE-TGKCLCNNGY- 171
                 :.|.|: ||.    .||.|..| .:.|..|..|  :|..   |..|.. ||:|:|:.||
Zfish   155 ALCNPITGACICAPGYHGWRCEDLCDHSTYGNNCQQKC--LCQN---NATCHHITGECVCSPGYT 214

  Fly   172 -----------QRDEKLKKCVPICQD--ACYH--GDCVAP----------------------NEC 199
                       :..::.::..| ||:  .|:|  |:|..|                      .||
Zfish   215 GAFCEDLCPPGKHGQQCEERCP-CQNGGVCHHVTGECSCPAGWMGMVCGQPCPTGRFGKNCSQEC 278

  Fly   200 RCHPGHEQRLGVPWICDP-----ICSSGCANGYCQGAEVCACKMGYAHKDNTLASGCEPVCNPPC 259
            :||.|        .||.|     :||||.....||.    .|::|      |...||...|.  |
Zfish   279 QCHNG--------GICSPSTGQCVCSSGYTGERCQD----QCQVG------TYGIGCSQACR--C 323

  Fly   260 TNGT-CIS-PGHCACSEGH--------VFAEGSRH-ECVPSCRSGCENGYCSSP--GRCECHEGF 311
            .||. |.. .|.|.|.:|:        :..:|... :|...|.....|.....|  |.|.|..|:
Zfish   324 VNGAQCYHVSGACLCEQGYTGESCEERICPDGQYGLKCDRKCPCNTNNTRSCHPMSGECSCQSGW 388

  Fly   312 EKTSPHRCSPTCRPG-----CGQNSRC-------AAPDTCACDVGYVFVNGSTTECEPFCPR--- 361
               |...|:.||.||     |.:..||       :....|.|..||   .||  :|...||.
Zfish   389 ---SGLYCNETCAPGFYGEACQEVCRCQNGADCHSVSGECICAPGY---KGS--DCAIACPPGTY 445

  Fly   362 --------NCRNGICSSP--GVCTCLEGFQALLSFYCIPVCSKTCIHG--------SCVAPN--- 405
                    :|:||...||  |.|:|..|:..:       .||..|..|        |||..|
Zfish   446 GINCTSLCSCKNGAICSPIDGSCSCQAGWHGV-------DCSINCPSGTWGLGCNLSCVCGNGGA 503

  Fly   406 ------ECRCFTGYRP----------------------------NPSLG---------ANVCEPI 427
                  :|.|..|:|.                            :||.|         ...|:.:
Zfish   504 CNALDGKCTCTPGWRGDRCDQHCQDGTYGLDCRERCDCSHADGCHPSTGHCRCLAGWTGIHCDSV 568

  Fly   428 CSQG-----------CVHGFCIAPE--ICQCDLGFIKRWATGTCEP-----HCPQKCVNSHCLGS 474
            |::|           |.:....:|:  .|:|..||........|.|     .|.|.|  .||:.|
Zfish   569 CAEGRWGPNCSLSCNCKNSASCSPDEGACECAPGFRGTTCQHICSPGVFGHRCSQAC--PHCVHS 631

  Fly   475 --------GVCRCYEGYKLRPGSTSICDPECQPG-----------C-RNGTCVEP--NSCACFAG 517
                    |.|.|..|:|     .::|:..|..|           | .|||| .|  .||.|:.|
Zfish   632 NGPCHHVTGQCECLPGFK-----GALCNEVCPSGKFGKNCGGSCTCTNNGTC-SPMDGSCQCYPG 690

  Fly   518 Y--EDTKVPY-------ECVPSCRPRCENGR-CSS-PGHCECDPGHVVTNSSE-------PNSCR 564
            :  .|...|.       .|:.:|  .|.||. ||: .|.|:|..|......::       ...|.
Zfish   691 WIGSDCSQPCPPGQWGPNCIHTC--NCHNGAFCSAYDGECKCTAGWTGLYCTQRCPLGFYGKDCV 753

  Fly   565 PQCQEQCIN-AEC-VAPEKCACLPRYRFLPDSSTECEPIC-----SKGCLSGQECVAPDTC---- 618
            ..|  ||.| |:| ....:|.|  |..|:   ...||..|     ..||....:|:...||
Zfish   754 QAC--QCENGADCNHISGQCTC--RTGFM---GRHCETKCPAGSYGYGCRQVCDCLNNSTCDHMT 811

  Fly   619 ----------------AGFESLISPTTGKHLAFHWSMF----VLAILLCLALVMIPLLVLREMQR 663
                            ||.....||.:....|.....:    :..|::.:.||:| ||:|..:.|
Zfish   812 GTCYCNPGWKGTRCDQAGGNIAESPNSLTSAALPMDSYQIGAITGIIILVLLVLI-LLLLFIIYR 875

  Fly   664 RRRNGDKQS------------------------------SRLIENPSY 681
            :::.|.:.|                              |....||||
Zfish   876 KKQKGKESSMPSVTYTPTMRANTDYAIAESLPQTEVLPNSNYFSNPSY 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC2	NP_788047.1	None
megf10	NP_001410717.1	EMI	28..97	CDD:462204	3/6 (50%)